NP_001177942.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,254 Da
NCBI Official Full Name
glutathione S-transferase omega-2 isoform 2
NCBI Official Synonym Full Names
glutathione S-transferase omega 2
NCBI Protein Information
glutathione S-transferase omega-2; GSTO-2; MMA(V) reductase; monomethylarsonic acid reductase; glutathione S-transferase omega 2-2; glutathione-S-transferase-like protein; bA127L20.1 (novel glutathione-S-transferase); glutathione-dependent dehydroascorbate reductase
UniProt Protein Name
Glutathione S-transferase omega-2
UniProt Synonym Protein Names
Glutathione S-transferase omega 2-2; GSTO 2-2; Glutathione-dependent dehydroascorbate reductase (EC:1.8.5.1); Monomethylarsonic acid reductase (EC:1.20.4.2); MMA(V) reductase
UniProt Synonym Gene Names
UniProt Entry Name
GSTO2_HUMAN
NCBI Summary for GSTO2
The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
UniProt Comments for GSTO2
GSTO2: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). Belongs to the GST superfamily. Omega family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Xenobiotic Metabolism - metabolism by cytochrome P450; Transferase; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Other Amino Acids Metabolism - glutathione
Chromosomal Location of Human Ortholog: 10q25.1
Cellular Component: cytosol
Molecular Function: glutathione transferase activity; glutathione dehydrogenase (ascorbate) activity; methylarsonate reductase activity; oxidoreductase activity
Biological Process: vitamin metabolic process; xenobiotic metabolic process; L-ascorbic acid metabolic process; water-soluble vitamin metabolic process
Research Articles on GSTO2
Precautions
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Pathways associated with GSTO2 elisa kit
Diseases associated with GSTO2 elisa kit
Organs/Tissues associated with GSTO2 elisa kit
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