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CGA elisa kit :: Human glycoprotein hormones, alpha polypeptide ELISA Kit

Scan QR to view Datasheet Catalog #    MBS928045
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

glycoprotein hormones, alpha polypeptide (CGA), ELISA Kit

 Also Known As   

Human Glycoprotein hormones alpha chain, CGA ELISA Kit

 Product Synonym Names    Human Glycoprotein hormones alpha chain (CGA) ELISA kit; CG-ALPHA; FSHA; GPHA1; GPHa; HCG; LHA; TSHA; chorionic gonadotropin; alpha polypeptide; follicle-stimulating hormone alpha subunit; glycoprotein hormones; alpha polypeptide
 Product Gene Name   

CGA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 MBS928045 Testing Data    Testing Data PDF
 OMIM    118850
 3D Structure    ModBase 3D Structure for P01215
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human CGA. No significant cross-reactivity or interference between human CGA and analogues was observed.
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 Samples    Serum, plasma, urine, cell culture supernates, tissue homogenates.
 Assay Type    Sandwich
 Detection Range    4 mIU/ml -12 0 mIU/ml.
 Sensitivity    1 mIU/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of CGA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CGA purchase    MBS928045 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the glycoprotein hormones, alpha polypeptide (CGA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 4 mIU/ml -12 0 mIU/ml in biological research samples containing CGA, with an estimated sensitivity of 1 mIU/ml. The ELISA analytical biochemical technique of the MBS928045 kit is based on CGA antibody-CGA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CGA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CGA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, urine, cell culture supernates, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for CGA elisa kit

   Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CGA has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP) conjugated antibody specific for CGA. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CGA bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of CGA elisa kit    CGA elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS928045
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NCBI/Uniprot data below describe general gene information for CGA. It may not necessarily be applicable to this product.
 NCBI GI #    4502787
 NCBI GeneID    1081
 NCBI Accession #    NP_000726.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000735.3 [Other Products]
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 UniProt Primary Accession #    P01215 [Other Products]
 Molecular Weight    13,075 Da
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 NCBI Official Full Name    glycoprotein hormones alpha chain isoform 2
 UniProt Protein Name    Glycoprotein hormones alpha chain
 UniProt Synonym Protein Names   
Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain
 Protein Family    Glycoprotein hormones
 UniProt Gene Name    CGA [Similar Products]
 UniProt Synonym Gene Names    CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha [Similar Products]
 UniProt Entry Name    GLHA_HUMAN
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 NCBI Summary for CGA    The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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 UniProt Comments for CGA    CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6q12-q21

Cellular Component: extracellular region

Molecular Function: protein binding; hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; positive regulation of cell proliferation; peptide hormone processing; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CGA elisa kitPathways associated with CGA elisa kit
 Reference Product  PubMed Publications
 CGB elisa kit  >119 publications with CGA and CGB
 LHB elisa kit  >25 publications with CGA and LHB
 FSHB elisa kit  >24 publications with CGA and FSHB
 TSHB elisa kit  >3 publications with CGA and TSHB
 LHCGR elisa kit  >1 publications with CGA and LHCGR
 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 Glycoprotein Hormones Pathway antibodies  Glycoprotein Hormones Pathway Diagram
Diseases associated with CGA elisa kitOrgans/Tissues associated with CGA elisa kit
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >242 publications with CGA and Adenocarcinoma
 Nervous System Diseases Antibodies  >134 publications with CGA and Nervous System Diseases
 Prostatic Diseases Antibodies  >120 publications with CGA and Prostatic Diseases
 Prostatic Neoplasms Antibodies  >118 publications with CGA and Prostatic Neoplasms
 Pancreatic Neoplasms Antibodies  >101 publications with CGA and Pancreatic Neoplasms
 Lung Neoplasms Antibodies  >97 publications with CGA and Lung Neoplasms
 Brain Diseases Antibodies  >93 publications with CGA and Brain Diseases
 Disease Progression Antibodies  >77 publications with CGA and Disease Progression
 Hyperplasia Antibodies  >70 publications with CGA and Hyperplasia
 Cardiovascular Diseases Antibodies  >70 publications with CGA and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >138 publications with CGA and Brain
 Lung Antibodies  >137 publications with CGA and Lung
 Stomach Antibodies  >120 publications with CGA and Stomach
 Liver Antibodies  >107 publications with CGA and Liver
 Thyroid Antibodies  >93 publications with CGA and Thyroid
 Muscle Antibodies  >79 publications with CGA and Muscle
 Heart Antibodies  >72 publications with CGA and Heart
 Vascular Antibodies  >71 publications with CGA and Vascular
 Pituitary Gland Antibodies  >66 publications with CGA and Pituitary Gland
 Skin Antibodies  >48 publications with CGA and Skin
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