NP_001273432.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
96,865 Da
NCBI Official Full Name
heat shock protein 105 kDa isoform 2
NCBI Official Synonym Full Names
heat shock 105kDa/110kDa protein 1
NCBI Official Synonym Symbols
HSP105; HSP105A; HSP105B; NY-CO-25 [Similar Products]
NCBI Protein Information
heat shock protein 105 kDa; antigen NY-CO-25; heat shock 105kD beta; heat shock 105kD alpha
UniProt Protein Name
Heat shock protein 105 kDa
UniProt Synonym Protein Names
Antigen NY-CO-25; Heat shock 110 kDa protein
UniProt Synonym Gene Names
UniProt Entry Name
HS105_HUMAN
UniProt Comments for HSPH1
HSP105: a molecular chaperone of the heat shock protein 70 family. Has ATPase activity. Expressed at especially high levels in mammalian brain and has been shown to suppress apoptosis in neuronal cells and to prevent the aggregation of proteins following heat shock. Known to interact with a variety of proteins including alpha-tubulin and the androgen receptor. Two alternatively spliced isoforms have been described.
Protein type: Chaperone; Heat shock protein
Chromosomal Location of Human Ortholog: 13q12.3
Cellular Component: nucleoplasm; microtubule; cytoplasm; extracellular region; cytosol
Molecular Function: protein binding; ATP binding; alpha-tubulin binding
Biological Process: receptor-mediated endocytosis; positive regulation of NK T cell activation; chaperone cofactor-dependent protein folding; positive regulation of MHC class I biosynthetic process; response to unfolded protein
Research Articles on HSPH1
Precautions
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Organs/Tissues associated with HSPH1 elisa kit
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