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HBG1 elisa kit :: Human hemoglobin, gamma A ELISA Kit

Scan QR to view Datasheet Catalog #    MBS924676 HBG1 elisa kit
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

hemoglobin, gamma A (HBG1), ELISA Kit

 Also Known As   

Human Hemoglobin subunit gamma-1, HBG1 ELISA Kit

 Product Synonym Names    Human Hemoglobin subunit gamma-1 (HBG1) ELISA kit; HBGA; HBGR; HSGGL1; PRO2979; A-gamma globin; gamma A hemoglobin; gamma globin; hemoglobin gamma-a chain; hemoglobin; gamma; regulator of; hemoglobin; gamma A
 Product Gene Name   

HBG1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    142200
 3D Structure    ModBase 3D Structure for P69891
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human HBG1. No significant cross-reactivity or interference between human HBG1 and analogues was observed.
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 Samples    Serum, plasma
 Assay Type    Competitive
 Detection Range    0.47 ?g/ml-30 ?g/ml.
 Sensitivity    The minimum detectable dose of human HBG1 is typically less than 0.12 ?g/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of HBG1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HBG1 purchase    MBS924676 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the hemoglobin, gamma A (HBG1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.47 ?g/ml-30 ?g/ml in biological research samples containing HBG1, with an estimated sensitivity of The minimum detectable dose of human HBG1 is typically less than 0.12 ?g/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. The ELISA analytical biochemical technique of the MBS924676 kit is based on HBG1 antibody-HBG1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HBG1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HBG1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for HBG1 elisa kit

   Principle of the assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with HBG1. Standards or samples are added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) conjugated antibody preparation specific for HBG1. The competitive inhibition reaction is launched between with pre-coated HBG1 and HBG1 in samples. A substrate solution is added to the wells and the color develops in opposite to the amount of HBG1 in the samples. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS924676
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NCBI/Uniprot data below describe general gene information for HBG1. It may not necessarily be applicable to this product.
 NCBI GI #    28302131
 NCBI GeneID    3047
 NCBI Accession #    NP_000550.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000559.2 [Other Products]
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 UniProt Primary Accession #    P69891 [Other Products]
 UniProt Secondary Accession #    P02096; P62027; Q549G1; Q8TDA1; Q96FH7 [Other Products]
 UniProt Related Accession #    P69891 [Other Products]
 Molecular Weight    16,140 Da
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 NCBI Official Full Name    hemoglobin subunit gamma-1
 NCBI Official Synonym Full Names    hemoglobin, gamma A
 NCBI Official Symbol    HBG1 [Similar Products]
 NCBI Official Synonym Symbols   
HBGA; HBGR; HBG-T2; HSGGL1; PRO2979
[Similar Products]
 NCBI Protein Information    hemoglobin subunit gamma-1; hb F Agamma; gamma globin; A-gamma globin; gamma-1-globin; gamma A hemoglobin; hemoglobin gamma-1 chain; hemoglobin gamma-a chain; hemoglobin, gamma, regulator of
 UniProt Protein Name    Hemoglobin subunit gamma-1
 UniProt Synonym Protein Names   
Gamma-1-globin; Hb F Agamma; Hemoglobin gamma-1 chain; Hemoglobin gamma-A chain
 Protein Family    Hemoglobin
 UniProt Gene Name    HBG1 [Similar Products]
 UniProt Synonym Gene Names    PRO2979 [Similar Products]
 UniProt Entry Name    HBG1_HUMAN
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 NCBI Summary for HBG1    The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HBG1    HBG1: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: hemoglobin complex; cytosol

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: oxygen transport; blood coagulation

Disease: Fetal Hemoglobin Quantitative Trait Locus 1
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 Research Articles on HBG1    1. There is synergism between developmental stage-specific recruitments of the ATF2 protein complex and expression of gamma-globin during erythropoiesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with HBG1 elisa kitOrgans/Tissues associated with HBG1 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with HBG1 and Nervous System Diseases
 Neoplasms Antibodies  >1 publications with HBG1 and Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with HBG1 and Blood
 Bone Antibodies  >1 publications with HBG1 and Bone
 Ovary Antibodies  >1 publications with HBG1 and Ovary
 Vascular Antibodies  >1 publications with HBG1 and Vascular
 Embryonic Tissue Antibodies  >1 publications with HBG1 and Embryonic Tissue
 Heart Antibodies  >1 publications with HBG1 and Heart
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