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HBG2 elisa kit :: Human hemoglobin, gamma G ELISA Kit

Scan QR to view Datasheet Catalog #    MBS924049 HBG2 elisa kit
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

hemoglobin, gamma G (HBG2), ELISA Kit

 Also Known As   

Human Hemoglobin subunit gamma-2, HBG2 ELISA Kit

 Product Synonym Names    Human Hemoglobin subunit gamma-2 (HBG2) ELISA kit; FLJ76540; G-gamma globin; OTTHUMP00000069638; abnormal hemoglobin; hemoglobin gamma-G; methemoglobin; hemoglobin; gamma G
 Product Gene Name   

HBG2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 MBS924049 Testing Data    Testing Data PDF
 OMIM    gene 613977
 3D Structure    ModBase 3D Structure for P69892
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human HBG2. No significant cross-reactivity or interference between human HBG2 and analogues was observed.
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 Samples    Serum, plasma.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of HBG2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HBG2 purchase    MBS924049 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the hemoglobin, gamma G (HBG2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HBG2. The ELISA analytical biochemical technique of the MBS924049 kit is based on HBG2 antibody-HBG2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HBG2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HBG2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for HBG2 elisa kit

   Principle of the Assay||This assay employs the qualitative enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with antibody. Samples are pipetted into the wells with antibody conjugated Horseradish Peroxidase (HRP). Any HBG2 present is bound by the immobilized antibody. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of human HBG2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS924049
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NCBI/Uniprot data below describe general gene information for HBG2. It may not necessarily be applicable to this product.
 NCBI GI #    6715607
 NCBI GeneID    3048
 NCBI Accession #    NP_000175.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000184.2 [Other Products]
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 UniProt Primary Accession #    P69892 [Other Products]
 UniProt Secondary Accession #    P02096; P62027; Q14491; Q68NH9; Q96FH6; Q96FH7; A8MZE0 [Other Products]
 UniProt Related Accession #    P69892 [Other Products]
 Molecular Weight    16,126 Da
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 NCBI Official Full Name    hemoglobin subunit gamma-2
 NCBI Official Synonym Full Names    hemoglobin, gamma G
 NCBI Official Symbol    HBG2 [Similar Products]
 NCBI Official Synonym Symbols   
TNCY; HBG-T1
[Similar Products]
 NCBI Protein Information    hemoglobin subunit gamma-2; hb F Ggamma; methemoglobin; gamma-2-globin; abnormal hemoglobin; G-gamma globin Paulinia; hemoglobin gamma-2 chain; hemoglobin gamma-G chain
 UniProt Protein Name    Hemoglobin subunit gamma-2
 UniProt Synonym Protein Names   
Gamma-2-globin; Hb F Ggamma; Hemoglobin gamma-2 chain; Hemoglobin gamma-G chain
 Protein Family    Hemoglobin
 UniProt Gene Name    HBG2 [Similar Products]
 UniProt Entry Name    HBG2_HUMAN
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 NCBI Summary for HBG2    The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HBG2    HBG2: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Defects in HBG2 are the cause of cyanosis transient neonatal (TNCY). TNCY is a disorder characterized by cyanosis in the fetus and neonate, due to a defect in the fetal hemoglobin chain which has reduced affinity for oxygen. Some patients develop anemia resulting from increased destruction of red cells containing abnormal or unstable hemoglobin. The cyanosis resolves spontaneously by 5 to 6 months of age or earlier, as the adult beta-globin chain is produced and replaces the fetal gamma- globin chain. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: hemoglobin complex; cytosol

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: oxygen transport; blood coagulation

Disease: Cyanosis, Transient Neonatal; Fetal Hemoglobin Quantitative Trait Locus 1
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 Research Articles on HBG2    1. Data suggest that segregation of BCL11A haplotype 2 indicating an involvement of this locus in Hb F expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HBG2 elisa kitPathways associated with HBG2 elisa kit
 Reference Product  PubMed Publications
 HBB elisa kit  >11 publications with HBG2 and HBB
 Products by Pathway  Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with HBG2 elisa kitOrgans/Tissues associated with HBG2 elisa kit
 Disease Name  Pubmed Publications
 Anemia, Hemolytic Antibodies  >9 publications with HBG2 and Anemia, Hemolytic
 Nervous System Diseases Antibodies  >2 publications with HBG2 and Nervous System Diseases
 Neoplasms Antibodies  >2 publications with HBG2 and Neoplasms
 Liver Neoplasms Antibodies  >1 publications with HBG2 and Liver Neoplasms
 Thrombosis Antibodies  >1 publications with HBG2 and Thrombosis
 Brain Diseases Antibodies  >1 publications with HBG2 and Brain Diseases
 Neoplasms, Experimental Antibodies  >1 publications with HBG2 and Neoplasms, Experimental
 Carcinoma, Hepatocellular Antibodies  >1 publications with HBG2 and Carcinoma, Hepatocellular
 Adenocarcinoma Antibodies  >1 publications with HBG2 and Adenocarcinoma
 Pain Antibodies  >1 publications with HBG2 and Pain
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13 publications with HBG2 and Blood
 Vascular Antibodies  >2 publications with HBG2 and Vascular
 Brain Antibodies  >2 publications with HBG2 and Brain
 Bone Antibodies  >1 publications with HBG2 and Bone
 Embryonic Tissue Antibodies  >1 publications with HBG2 and Embryonic Tissue
 Liver Antibodies  >1 publications with HBG2 and Liver
 Heart Antibodies  >1 publications with HBG2 and Heart
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