NP_006034.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,501 Da
NCBI Official Full Name
heparan sulfate glucosamine 3-O-sulfotransferase 2
NCBI Official Synonym Full Names
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
NCBI Official Synonym Symbols
NCBI Protein Information
heparan sulfate glucosamine 3-O-sulfotransferase 2; 3-OST-2; h3-OST-2; heparan sulfate 3-O-sulfotransferase 2; heparin-glucosamine 3-O-sulfotransferase; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2
UniProt Protein Name
Heparan sulfate glucosamine 3-O-sulfotransferase 2
UniProt Synonym Protein Names
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2; 3-OST-2; Heparan sulfate 3-O-sulfotransferase 2; h3-OST-2
UniProt Synonym Gene Names
3OST2; UNQ2442/PRO5004; 3-OST-2; Heparan sulfate 3-O-sulfotransferase 2; h3-OST-2 [Similar Products]
UniProt Entry Name
HS3S2_HUMAN
NCBI Summary for HS3ST2
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. This gene is expressed predominantly in brain and may play a role in the nervous system. [provided by RefSeq, Jul 2008]
UniProt Comments for HS3ST2
HS3ST2: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in GlcA2S-GlcNS. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. Belongs to the sulfotransferase 1 family.
Protein type: Transferase; Membrane protein, integral; EC 2.8.2.29; Glycan Metabolism - heparan sulfate biosynthesis
Chromosomal Location of Human Ortholog: 16p12
Cellular Component: Golgi membrane; integral to membrane
Molecular Function: sulfotransferase activity; [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity
Biological Process: circadian rhythm; glycosaminoglycan biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis
Research Articles on HS3ST2
Precautions
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Pathways associated with HS3ST2 elisa kit
Diseases associated with HS3ST2 elisa kit
Organs/Tissues associated with HS3ST2 elisa kit
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