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HMGA1 elisa kit :: Human high mobility group AT-hook 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9322132 HMGA1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

high mobility group AT-hook 1 (HMGA1), ELISA Kit

 Also Known As   

Human High mobility group protein HMG-I/HMG-Y, HMGA1 ELISA Kit

 Product Synonym Names    Human High mobility group protein HMG-I/HMG-Y (HMGA1) ELISA kit; HMG-R; HMGA1A; HMGIY; MGC12816; MGC4242; MGC4854; OTTHUMP00000016223; OTTHUMP00000016224; high-mobility group (nonhistone chromosomal) protein isoforms I and Y; nonhistone chromosomal high-mobility gro; high mobility group AT-hook 1
 Product Gene Name   

HMGA1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    600701
 3D Structure    ModBase 3D Structure for P17096
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of HMGA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HMGA1 purchase    MBS9322132 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the high mobility group AT-hook 1 (HMGA1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HMGA1. The ELISA analytical biochemical technique of the MBS9322132 kit is based on HMGA1 antibody-HMGA1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HMGA1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HMGA1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for HMGA1. It may not necessarily be applicable to this product.
 NCBI GI #    4504433
 NCBI GeneID    3159
 NCBI Accession #    NP_002122.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002131.3 [Other Products]
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 UniProt Primary Accession #    P17096 [Other Products]
 UniProt Secondary Accession #    P10910; Q5T6U9; Q9UKB0 [Other Products]
 UniProt Related Accession #    P17096 [Other Products]
 Molecular Weight    11,676 Da
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 NCBI Official Full Name    high mobility group protein HMG-I/HMG-Y isoform b
 NCBI Official Synonym Full Names    high mobility group AT-hook 1
 NCBI Official Symbol    HMGA1 [Similar Products]
 NCBI Official Synonym Symbols   
HMG-R; HMGIY; HMGA1A
[Similar Products]
 NCBI Protein Information    high mobility group protein HMG-I/HMG-Y; HMG-I(Y); high mobility group protein R; high mobility group protein A1; nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y; high-mobility group (nonhistone chromosomal) protein isoforms I and Y
 UniProt Protein Name    High mobility group protein HMG-I/HMG-Y
 UniProt Synonym Protein Names   
High mobility group AT-hook protein 1; High mobility group protein A1; High mobility group protein R
 Protein Family    High mobility group protein
 UniProt Gene Name    HMGA1 [Similar Products]
 UniProt Synonym Gene Names    HMGIY; HMG-I(Y); High mobility group protein A1 [Similar Products]
 UniProt Entry Name    HMGA1_HUMAN
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 NCBI Summary for HMGA1    This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HMGA1    HMGA1: HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions. A chromosomal aberration involving HMGA1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with RAD51B. Belongs to the HMGA family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 6p21

Cellular Component: nucleoplasm; transcription factor complex; focal adhesion; nucleus; cytosol

Molecular Function: retinoid X receptor binding; peroxisome proliferator activated receptor binding; protein binding; DNA-(apurinic or apyrimidinic site) lyase activity; enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; DNA binding; AT DNA binding; retinoic acid receptor binding; 5'-deoxyribose-5-phosphate lyase activity; transcription factor binding

Biological Process: DNA unwinding during replication; viral reproduction; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; response to virus; DNA catabolic process, endonucleolytic; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; negative regulation of chromatin silencing; nucleosome disassembly; base-excision repair; protein complex assembly; negative regulation of transcription, DNA-dependent
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 Research Articles on HMGA1    1. Results support a model in which the HMGA1/TAR interaction prevents the binding of transcription-activating cellular co-factors and Tat, subsequently leading to reduced HIV-1 transcription.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HMGA1 elisa kitPathways associated with HMGA1 elisa kit
 Reference Product  PubMed Publications
 JUN elisa kit  >20 publications with HMGA1 and JUN
 SP1 elisa kit  >14 publications with HMGA1 and SP1
 ATF2 elisa kit  >9 publications with HMGA1 and ATF2
 HIPK2 elisa kit  >6 publications with HMGA1 and HIPK2
 INSR elisa kit  >6 publications with HMGA1 and INSR
 IRF1 elisa kit  >4 publications with HMGA1 and IRF1
 PRMT6 elisa kit  >3 publications with HMGA1 and PRMT6
 PPARG elisa kit  >3 publications with HMGA1 and PPARG
 CREBBP elisa kit  >3 publications with HMGA1 and CREBBP
 CDK1 elisa kit  >2 publications with HMGA1 and CDK1
 Products by Pathway  Pathway Diagram
 2-LTR Circle Formation Pathway antibodies  2-LTR Circle Formation Pathway Diagram
 APOBEC3G Mediated Resistance To HIV-1 Infection Pathway antibodies  APOBEC3G Mediated Resistance To HIV-1 Infection Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Autointegration Results In Viral DNA Circles Pathway antibodies  Autointegration Results In Viral DNA Circles Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Early Phase Of HIV Life Cycle Pathway antibodies  Early Phase Of HIV Life Cycle Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 Host Interactions Of HIV Factors Pathway antibodies  Host Interactions Of HIV Factors Pathway Diagram
 IL-4 Signaling Pathway antibodies  IL-4 Signaling Pathway Diagram
Diseases associated with HMGA1 elisa kitOrgans/Tissues associated with HMGA1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >281 publications with HMGA1 and Neoplasms
 Carcinoma Antibodies  >83 publications with HMGA1 and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >72 publications with HMGA1 and Cell Transformation, Neoplastic
 Chromosome Aberrations Antibodies  >62 publications with HMGA1 and Chromosome Aberrations
 Uterine Neoplasms Antibodies  >37 publications with HMGA1 and Uterine Neoplasms
 Adenocarcinoma Antibodies  >35 publications with HMGA1 and Adenocarcinoma
 Breast Neoplasms Antibodies  >33 publications with HMGA1 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >30 publications with HMGA1 and Neoplasms, Experimental
 Pancreatic Neoplasms Antibodies  >22 publications with HMGA1 and Pancreatic Neoplasms
 Head and Neck Neoplasms Antibodies  >21 publications with HMGA1 and Head and Neck Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >54 publications with HMGA1 and Blood
 Lung Antibodies  >39 publications with HMGA1 and Lung
 Thyroid Antibodies  >35 publications with HMGA1 and Thyroid
 Muscle Antibodies  >34 publications with HMGA1 and Muscle
 Embryonic Tissue Antibodies  >32 publications with HMGA1 and Embryonic Tissue
 Liver Antibodies  >25 publications with HMGA1 and Liver
 Vascular Antibodies  >22 publications with HMGA1 and Vascular
 Brain Antibodies  >18 publications with HMGA1 and Brain
 Prostate Antibodies  >16 publications with HMGA1 and Prostate
 Heart Antibodies  >13 publications with HMGA1 and Heart
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