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HIST1H2AC elisa kit :: Human histone cluster 1, H2ac ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9333153 HIST1H2AC elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

histone cluster 1, H2ac (HIST1H2AC), ELISA Kit

★Popular Item★
 Also Known As   

Human Histone H2A type 1-C, HIST1H2AC ELISA Kit

 Product Synonym Names    Human Histone H2A type 1-C (HIST1H2AC) ELISA kit; H2A/l; H2AFL; MGC99519; dJ221C16.4; H2A histone family; member L; OTTHUMP00000016145; histone 1; H2ac; histone H2AC; histone cluster 1; H2ac
 Product Gene Name   

HIST1H2AC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    602794
 3D Structure    ModBase 3D Structure for Q93077
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.5 ng/ml - 16 ng/ml
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HIST1H2AC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HIST1H2AC purchase    MBS9333153 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the histone cluster 1, H2ac (HIST1H2AC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.5 ng/ml - 16 ng/ml in biological research samples containing HIST1H2AC, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9333153 kit is based on HIST1H2AC antibody-HIST1H2AC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HIST1H2AC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HIST1H2AC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for HIST1H2AC elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HIST1H2AC (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9333153. Click to request current manual
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NCBI/Uniprot data below describe general gene information for HIST1H2AC. It may not necessarily be applicable to this product.
 NCBI GI #    4504245
 NCBI GeneID    8334
 NCBI Accession #    NP_003503.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003512.3 [Other Products]
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 UniProt Primary Accession #    Q93077 [Other Products]
 UniProt Secondary Accession #    O00775; O00776; O00777; O00778; Q540R1; B2R4F7 [Other Products]
 UniProt Related Accession #    Q93077 [Other Products]
 Molecular Weight    14,105 Da
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 NCBI Official Full Name    histone H2A type 1-C
 NCBI Official Synonym Full Names    histone cluster 1, H2ac
 NCBI Official Symbol    HIST1H2AC [Similar Products]
 NCBI Official Synonym Symbols   
H2A/l; H2AFL; dJ221C16.4
[Similar Products]
 NCBI Protein Information    histone H2A type 1-C; histone H2AC; histone H2A/l; histone 1, H2ac; H2A histone family, member L
 UniProt Protein Name    Histone H2A type 1-C
 UniProt Synonym Protein Names   
Histone H2A/l
 UniProt Gene Name    HIST1H2AC [Similar Products]
 UniProt Synonym Gene Names    H2AFL [Similar Products]
 UniProt Entry Name    H2A1C_HUMAN
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 NCBI Summary for HIST1H2AC    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HIST1H2AC    H2AL: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H2A family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 6p22.1

Cellular Component: nucleosome; nucleus

Molecular Function: DNA binding; protein heterodimerization activity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with HIST1H2AC elisa kitDiseases associated with HIST1H2AC elisa kit
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Chromosome Maintenance Pathway antibodies  Chromosome Maintenance Pathway Diagram
 Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway antibodies  Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Meiosis Pathway antibodies  Meiosis Pathway Diagram
 Meiotic Recombination Pathway antibodies  Meiotic Recombination Pathway Diagram
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with HIST1H2AC and Breast Neoplasms
 Neoplasms Antibodies  >1 publications with HIST1H2AC and Neoplasms
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