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HABP2 elisa kit :: Human hyaluronan binding protein 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS906566
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
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 Product Name   

hyaluronan binding protein 2 (HABP2), ELISA Kit

★Popular Item★
 Also Known As   

Human Hyaluronan-binding protein 2, HABP2 ELISA Kit

 Product Synonym Names    Human Hyaluronan-binding protein 2 (HABP2) ELISA kit; FSAP; HABP; HGFAL; PHBP; factor VII activating protein; hepatocyte growth factor activator-like protein; hyaluronic acid binding protein 2; plasma hyaluronan binding protein; hyaluronan binding protein 2
 Product Gene Name   

HABP2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS906566 Testing Data    Testing Data PDF
 OMIM    603924
 3D Structure    ModBase 3D Structure for Q14520
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human HABP2. No significant cross-reactivity or interference between human HABP2 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Detection Range    0.312 ng/ml -20 ng/mL
 Sensitivity    <0.078 ng/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HABP2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HABP2 purchase    MBS906566 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the hyaluronan binding protein 2 (HABP2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.312 ng/ml -20 ng/mL in biological research samples containing HABP2, with an estimated sensitivity of <0.078 ng/mL. The ELISA analytical biochemical technique of the MBS906566 kit is based on HABP2 antibody-HABP2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HABP2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HABP2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for HABP2 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for HABP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any HABP2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for HABP2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of HABP2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of HABP2 elisa kit    HABP2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS906566. Click to request current manual
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NCBI/Uniprot data below describe general gene information for HABP2. It may not necessarily be applicable to this product.
 NCBI GI #    295054188
 NCBI GeneID    3026
 NCBI Accession #    NP_001171131.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001177660.1 [Other Products]
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 UniProt Primary Accession #    Q14520 [Other Products]
 UniProt Secondary Accession #    O00663; A8K467; B7Z8U5; F5H5M6 [Other Products]
 UniProt Related Accession #    Q14520 [Other Products]
 Molecular Weight    62,672 Da
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 NCBI Official Full Name    hyaluronan-binding protein 2 isoform 2
 NCBI Official Synonym Full Names    hyaluronan binding protein 2
 NCBI Official Symbol    HABP2 [Similar Products]
 NCBI Official Synonym Symbols   
FSAP; HABP; PHBP; HGFAL
[Similar Products]
 NCBI Protein Information    hyaluronan-binding protein 2; factor VII activating protein; factor VII-activating protease; factor seven-activating protease; hyaluronic acid binding protein 2; plasma hyaluronan binding protein; plasma hyaluronan-binding protein; hepatocyte growth factor activator-like protein
 UniProt Protein Name    Hyaluronan-binding protein 2
 UniProt Synonym Protein Names   
Factor VII-activating protease; Factor seven-activating protease; FSAP; Hepatocyte growth factor activator-like protein; Plasma hyaluronan-binding proteinCleaved into the following 4 chains:Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form
 Protein Family    Hyaluronan-binding protein
 UniProt Gene Name    HABP2 [Similar Products]
 UniProt Synonym Gene Names    HGFAL; PHBP; FSAP [Similar Products]
 UniProt Entry Name    HABP2_HUMAN
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 NCBI Summary for HABP2    The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
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 UniProt Comments for HABP2    HABP2: Cleaves the alpha-chain at multiple sites and the beta- chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro- urokinase) to the active two chain form. Activates coagulation factor VII. Belongs to the peptidase S1 family.

Protein type: Protease; Secreted, signal peptide; Cell adhesion; Motility/polarity/chemotaxis; Secreted; EC 3.4.21.-

Chromosomal Location of Human Ortholog: 10q25.3

Cellular Component: extracellular space; extracellular region

Molecular Function: glycosaminoglycan binding; serine-type endopeptidase activity

Biological Process: proteolysis; cell adhesion

Disease: Thrombophilia Due To Thrombin Defect; Thyroid Cancer, Nonmedullary, 5
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 Research Articles on HABP2    1. FSAP activates the NF-kappaB pathway and the associated downstream pro-inflammatory factors in monocytic cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HABP2 elisa kitDiseases associated with HABP2 elisa kit
 Reference Product  PubMed Publications
 KNG1 elisa kit  >1 publications with HABP2 and KNG1
 Disease Name  Pubmed Publications
 Thrombosis Antibodies  >18 publications with HABP2 and Thrombosis
 Atherosclerosis Antibodies  >7 publications with HABP2 and Atherosclerosis
 Nervous System Diseases Antibodies  >6 publications with HABP2 and Nervous System Diseases
 Brain Diseases Antibodies  >6 publications with HABP2 and Brain Diseases
 Neoplasms Antibodies  >5 publications with HABP2 and Neoplasms
 Fibrosis Antibodies  >5 publications with HABP2 and Fibrosis
 Cerebrovascular Disorders Antibodies  >5 publications with HABP2 and Cerebrovascular Disorders
 Thrombophilia Antibodies  >4 publications with HABP2 and Thrombophilia
 Liver Diseases Antibodies  >3 publications with HABP2 and Liver Diseases
 Lung Neoplasms Antibodies  >3 publications with HABP2 and Lung Neoplasms
Organs/Tissues associated with HABP2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >37 publications with HABP2 and Blood
 Muscle Antibodies  >10 publications with HABP2 and Muscle
 Lung Antibodies  >7 publications with HABP2 and Lung
 Liver Antibodies  >6 publications with HABP2 and Liver
 Heart Antibodies  >2 publications with HABP2 and Heart
 Connective Tissue Antibodies  >1 publications with HABP2 and Connective Tissue
 Embryonic Tissue Antibodies  >1 publications with HABP2 and Embryonic Tissue
 Pancreas Antibodies  >1 publications with HABP2 and Pancreas
 Kidney Antibodies  >1 publications with HABP2 and Kidney
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