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ITPK1 elisa kit :: Human inositol 1, 3, 4-triphosphate 5/6 kinase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9322565 ITPK1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

inositol 1, 3, 4-triphosphate 5/6 kinase (ITPK1), ELISA Kit

 Also Known As   

Human Inositol-tetrakisphosphate 1-kinase, ITPK1 ELISA Kit

 Product Synonym Names    Human Inositol-tetrakisphosphate 1-kinase (ITPK1) ELISA kit; ITRPK1; inositol 1; 3; 4-trisphosphate 5/6 kinase; inositol-tetrakisphosphate 1-kinase; inositol 1; 3; 4-triphosphate 5/6 kinase
 Product Gene Name   

ITPK1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    601838
 3D Structure    ModBase 3D Structure for Q13572
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ITPK1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ITPK1 purchase    MBS9322565 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the inositol 1, 3, 4-triphosphate 5/6 kinase (ITPK1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITPK1. The ELISA analytical biochemical technique of the MBS9322565 kit is based on ITPK1 antibody-ITPK1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITPK1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITPK1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ITPK1. It may not necessarily be applicable to this product.
 NCBI GI #    217272844
 NCBI GeneID    3705
 NCBI Accession #    NP_001136065.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001142593.1 [Other Products]
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 UniProt Primary Accession #    Q13572 [Other Products]
 UniProt Secondary Accession #    Q9BTL6; Q9H2E7 [Other Products]
 UniProt Related Accession #    Q13572 [Other Products]
 Molecular Weight    45,621 Da
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 NCBI Official Full Name    inositol-tetrakisphosphate 1-kinase isoform a
 NCBI Official Synonym Full Names    inositol-tetrakisphosphate 1-kinase
 NCBI Official Symbol    ITPK1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    inositol-tetrakisphosphate 1-kinase; ins(1,3,4)P(3) 5/6-kinase; inositol-triphosphate 5/6-kinase; inositol 1,3,4-triphosphate 5/6 kinase; inositol 1,3,4-trisphosphate 5/6 kinase; inositol 1,3,4-trisphosphate 5/6-kinase
 UniProt Protein Name    Inositol-tetrakisphosphate 1-kinase
 UniProt Synonym Protein Names   
Inositol 1,3,4-trisphosphate 5/6-kinase (EC:; Inositol-triphosphate 5/6-kinase; Ins(1,3,4)P(3) 5/6-kinase
 Protein Family    Inositol-tetrakisphosphate 1-kinase
 UniProt Gene Name    ITPK1 [Similar Products]
 UniProt Synonym Gene Names    Inositol-triphosphate 5/6-kinase; Ins(1,3,4)P(3) 5/6-kinase [Similar Products]
 UniProt Entry Name    ITPK1_HUMAN
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 UniProt Comments for ITPK1    ITPK1: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain. Belongs to the ITPK1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - inositol phosphate; Kinase, lipid; EC; EC; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q31

Cellular Component: cytosol

Molecular Function: inositol tetrakisphosphate 1-kinase activity; magnesium ion binding; isomerase activity; catalytic activity; ATP binding

Biological Process: inositol phosphate metabolic process; dephosphorylation; signal transduction; blood coagulation; phosphorylation; inositol trisphosphate metabolic process
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 Research Articles on ITPK1    1. Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ITPK1 elisa kitDiseases associated with ITPK1 elisa kit
 Products by Pathway  Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis II (mammalian) Pathway Diagram
 1D-myo-inositol Hexakisphosphate Biosynthesis V (from Ins(1,3,4)P3) Pathway antibodies  1D-myo-inositol Hexakisphosphate Biosynthesis V (from Ins(1,3,4)P3) Pathway Diagram
 D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with ITPK1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >2 publications with ITPK1 and Congenital Abnormalities
 Fibrosis Antibodies  >2 publications with ITPK1 and Fibrosis
 Nervous System Malformations Antibodies  >2 publications with ITPK1 and Nervous System Malformations
 Disease Models, Animal Antibodies  >1 publications with ITPK1 and Disease Models, Animal
Organs/Tissues associated with ITPK1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with ITPK1 and Embryonic Tissue
 Muscle Antibodies  >1 publications with ITPK1 and Muscle
 Lung Antibodies  >1 publications with ITPK1 and Lung
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