NP_002153.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
59,541 Da
NCBI Official Full Name
intercellular adhesion molecule 3
NCBI Official Synonym Full Names
intercellular adhesion molecule 3
NCBI Protein Information
intercellular adhesion molecule 3; ICAM-3; intercellular adhesion molecule-3
UniProt Protein Name
Intercellular adhesion molecule 3
UniProt Synonym Protein Names
CDw50; ICAM-R; CD_antigen: CD50
UniProt Synonym Gene Names
UniProt Entry Name
ICAM3_HUMAN
NCBI Summary for ICAM 3
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq, Jul 2008]
UniProt Comments for ICAM 3
ICAM3: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. Belongs to the immunoglobulin superfamily. ICAM family.
Protein type: Immunoglobulin superfamily; Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p13.3-p13.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: integrin binding; protein binding; receptor binding
Biological Process: extracellular matrix organization and biogenesis; regulation of immune response; cell-cell adhesion; cell adhesion
Research Articles on ICAM 3
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Products associated with ICAM 3 elisa kit
Pathways associated with ICAM 3 elisa kit
Diseases associated with ICAM 3 elisa kit
Organs/Tissues associated with ICAM 3 elisa kit
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