NP_003250.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
97,116 Da
NCBI Official Full Name
intercellular adhesion molecule 5
NCBI Official Synonym Full Names
intercellular adhesion molecule 5, telencephalin
NCBI Official Synonym Symbols
NCBI Protein Information
intercellular adhesion molecule 5; ICAM-5; telencephalin
UniProt Protein Name
Intercellular adhesion molecule 5
UniProt Synonym Protein Names
Telencephalin
UniProt Synonym Gene Names
UniProt Entry Name
ICAM5_HUMAN
NCBI Summary for ICAM5
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]
UniProt Comments for ICAM5
ICAM5: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). Belongs to the immunoglobulin superfamily. ICAM family.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: integrin binding; protein binding
Biological Process: cell-cell adhesion; cell adhesion; phagocytosis
Research Articles on ICAM5
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Products associated with ICAM5 elisa kit
Diseases associated with ICAM5 elisa kit
Organs/Tissues associated with ICAM5 elisa kit
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