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IL1R2 elisa kit :: Human interleukin 1 receptor, type II ELISA Kit

Scan QR to view Datasheet Catalog #    MBS703236
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $625 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,595 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,905 +6 FREE 8GB USB
 
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 Product Name   

interleukin 1 receptor, type II (IL1R2), ELISA Kit

★Popular Item★
 Also Known As   

Human soluble interleukin-1 receptor II, IL-1sRII ELISA Kit

 Product Synonym Names    Human soluble interleukin-1 receptor II; IL-1sRII ELISA kit; CD121b; IL1RB; MGC47725; antigen CDw121b; type II interleukin-1 receptor; beta; interleukin 1 receptor; type II
 Product Gene Name   

IL1R2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS703236 Testing Data    Testing Data PDF
 OMIM    147811
 3D Structure    ModBase 3D Structure for P27930
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human IL1R2. No significant cross-reactivity or interference between Human IL1R2 and analogues was observed.
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 Samples    Serum, plasma
 Detection Range    0.312 ng/ml-20 ng/ml
 Sensitivity    0.078 ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL1R2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL1R2 purchase    MBS703236 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interleukin 1 receptor, type II (IL1R2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.312 ng/ml-20 ng/ml in biological research samples containing IL1R2, with an estimated sensitivity of 0.078 ng/ml. The ELISA analytical biochemical technique of the MBS703236 kit is based on IL1R2 antibody-IL1R2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL1R2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL1R2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL1R2 elisa kit

   Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to IL-1SRII. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for IL-1SRII and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain IL-1SR II , biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of IL-1SRII in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of IL1R2 elisa kit    IL1R2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS703236. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL1R2. It may not necessarily be applicable to this product.
 NCBI GI #    387527984
 NCBI GeneID    7850
 NCBI Accession #    NP_001248348.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001261419.1 [Other Products]
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 UniProt Primary Accession #    P27930 [Other Products]
 UniProt Secondary Accession #    Q6LCE6; Q9UE68; D3DVJ5 [Other Products]
 UniProt Related Accession #    P27930 [Other Products]
 Molecular Weight    45,421 Da
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 NCBI Official Full Name    interleukin-1 receptor type 2 isoform 2
 NCBI Official Synonym Full Names    interleukin 1 receptor, type II
 NCBI Official Symbol    IL1R2 [Similar Products]
 NCBI Official Synonym Symbols   
IL1RB; CD121b; IL1R2c; CDw121b; IL-1R-2; IL-1RT2; IL-1RT-2
[Similar Products]
 NCBI Protein Information    interleukin-1 receptor type 2; IL-1R-beta; antigen CDw121b; IL-1 type II receptor; interleukin-1 receptor beta; interleukin-1 receptor type II; CD121 antigen-like family member B; type II interleukin-1 receptor, beta; interleukin 1 receptor type II variant 3
 UniProt Protein Name    Interleukin-1 receptor type 2
 UniProt Synonym Protein Names   
CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD_antigen: CD121bCleaved into the following 2 chains:Interleukin-1 receptor type 2, membrane form; mIL-1R2; mIL-1RII; Interleukin-1 receptor type 2, soluble form; sIL-1R2; sIL-1RII
 Protein Family    Interleukin-1 receptor
 UniProt Gene Name    IL1R2 [Similar Products]
 UniProt Synonym Gene Names    IL1RB; IL-1R-2; IL-1RT-2; IL-1RT2; IL-1R-beta; mIL-1R2; mIL-1RII; sIL-1R2; sIL-1RII [Similar Products]
 UniProt Entry Name    IL1R2_HUMAN
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 NCBI Summary for IL1R2    The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
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 UniProt Comments for IL1R2    Function: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.4 PublicationsManual assertion based on experiment in:Ref.8
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 Research Articles on IL1R2    1. Data indicate a significant increase in the levels of IL-8, TNF-alpha and IL-1R2 in the CSF of both meningitis groups as compared to controls, and the concentrations of IFN-gamma and IL-1 differed significantly only between the mumps group and control.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL1R2 elisa kitPathways associated with IL1R2 elisa kit
 Reference Product  PubMed Publications
 IL1R1 elisa kit  >16 publications with IL1R2 and IL1R1
 IL1B elisa kit  >12 publications with IL1R2 and IL1B
 IL1RN elisa kit  >5 publications with IL1R2 and IL1RN
 IL1A elisa kit  >3 publications with IL1R2 and IL1A
 IL1RAP elisa kit  >3 publications with IL1R2 and IL1RAP
 NFKB1 elisa kit  >2 publications with IL1R2 and NFKB1
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Apoptosis Modulation And Signaling Pathway antibodies  Apoptosis Modulation And Signaling Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
Diseases associated with IL1R2 elisa kitOrgans/Tissues associated with IL1R2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >23 publications with IL1R2 and Inflammation
 Necrosis Antibodies  >10 publications with IL1R2 and Necrosis
 Lung Diseases Antibodies  >10 publications with IL1R2 and Lung Diseases
 Cardiovascular Diseases Antibodies  >8 publications with IL1R2 and Cardiovascular Diseases
 Spondylitis, Ankylosing Antibodies  >6 publications with IL1R2 and Spondylitis, Ankylosing
 Hypersensitivity Antibodies  >5 publications with IL1R2 and Hypersensitivity
 Colitis, Ulcerative Antibodies  >4 publications with IL1R2 and Colitis, Ulcerative
 Heart Diseases Antibodies  >4 publications with IL1R2 and Heart Diseases
 Lung Neoplasms Antibodies  >3 publications with IL1R2 and Lung Neoplasms
 Pain Antibodies  >3 publications with IL1R2 and Pain
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >23 publications with IL1R2 and Blood
 Uterus Antibodies  >10 publications with IL1R2 and Uterus
 Lung Antibodies  >7 publications with IL1R2 and Lung
 Skin Antibodies  >3 publications with IL1R2 and Skin
 Kidney Antibodies  >2 publications with IL1R2 and Kidney
 Lymph Node Antibodies  >2 publications with IL1R2 and Lymph Node
 Ovary Antibodies  >1 publications with IL1R2 and Ovary
 Prostate Antibodies  >1 publications with IL1R2 and Prostate
 Placenta Antibodies  >1 publications with IL1R2 and Placenta
 Liver Antibodies  >1 publications with IL1R2 and Liver
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