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IL17RD elisa kit :: Human interleukin 17 receptor D ELISA Kit

Scan QR to view Datasheet Catalog #    MBS943113
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
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 Product Name   

interleukin 17 receptor D (IL17RD), ELISA Kit

★Popular Item★
 Also Known As   

Human Interleukin-17 receptor D, IL17RD ELISA Kit

 Product Synonym Names    Human Interleukin-17 receptor D (IL17RD) ELISA kit; DKFZp434N1928; FLJ35755; IL-17RD; IL17RLM; MGC133309; SEF; ; interleukin 17 receptor D
 Product Gene Name   

IL17RD elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS943113 Testing Data    Testing Data PDF
 OMIM    gene 615267
 3D Structure    ModBase 3D Structure for Q8NFM7
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human IL17RD. No significant cross-reactivity or interference between Human IL17RD and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    25 pg/ml-1600 pg/ml
 Sensitivity    6.25 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL17RD elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL17RD purchase    MBS943113 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interleukin 17 receptor D (IL17RD) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 25 pg/ml-1600 pg/ml in biological research samples containing IL17RD, with an estimated sensitivity of 6.25 pg/ml. The ELISA analytical biochemical technique of the MBS943113 kit is based on IL17RD antibody-IL17RD antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL17RD antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL17RD. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL17RD elisa kit

   For Sample For the quantitative determination of human interleukin-17 receptor D (IL17RD) concentrations in serum, plasma, tissue homogenates.

PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL17RD has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL17RD present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL17RD is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL17RD bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of IL17RD elisa kit    IL17RD elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS943113. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL17RD. It may not necessarily be applicable to this product.
 NCBI GI #    166063983
 NCBI GeneID    54756
 NCBI Accession #    NP_060033.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_017563.3 [Other Products]
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 UniProt Primary Accession #    Q8NFM7 [Other Products]
 UniProt Secondary Accession #    Q2NKP7; Q58EZ7; Q6RVF4; Q6UWI5; Q8N113; Q8NFS0; Q9UFA0 [Other Products]
 UniProt Related Accession #    Q8NFM7 [Other Products]
 Molecular Weight    82,411 Da
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 NCBI Official Full Name    interleukin-17 receptor D
 NCBI Official Synonym Full Names    interleukin 17 receptor D
 NCBI Official Symbol    IL17RD [Similar Products]
 NCBI Official Synonym Symbols   
SEF; HH18; IL-17RD; IL17RLM
[Similar Products]
 NCBI Protein Information    interleukin-17 receptor D; hSef; IL17Rhom; sef homolog; IL-17 receptor D; interleukin-17 receptor-like protein
 UniProt Protein Name    Interleukin-17 receptor D
 UniProt Synonym Protein Names   
IL17Rhom; Interleukin-17 receptor-like protein; Sef homolog; hSef
 Protein Family    Interleukin-17 receptor
 UniProt Gene Name    IL17RD [Similar Products]
 UniProt Synonym Gene Names    IL17RLM; SEF; UNQ6115/PRO20026; IL-17 receptor D; IL-17RD; hSef [Similar Products]
 UniProt Entry Name    I17RD_HUMAN
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 NCBI Summary for IL17RD    This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin (PMID: 19079364). The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling (PMID: 21663947, 18096367). [provided by RefSeq, Nov 2011]
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 UniProt Comments for IL17RD    IL17RD: Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p14.3

Cellular Component: nucleoplasm; Golgi membrane; Golgi apparatus; integral to plasma membrane

Molecular Function: interleukin-17 receptor activity

Biological Process: cytokine and chemokine mediated signaling pathway

Disease: Hypogonadotropic Hypogonadism 18 With Or Without Anosmia
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 Research Articles on IL17RD    1. These results reveal Sef-S actives Lys63-linked TAK1 polyubiquitination on lysine 209, induces TAK1-mediated JNK and p38 activation and also results apoptosis in 293T cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL17RD elisa kitPathways associated with IL17RD elisa kit
 Reference Product  PubMed Publications
 FGFR1 elisa kit  >3 publications with IL17RD and FGFR1
 Products by Pathway  Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By FGFR Pathway antibodies  Signaling By FGFR Pathway Diagram
Diseases associated with IL17RD elisa kitOrgans/Tissues associated with IL17RD elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with IL17RD and Neoplasms
 Prostatic Diseases Antibodies  >4 publications with IL17RD and Prostatic Diseases
 Inflammation Antibodies  >4 publications with IL17RD and Inflammation
 Prostatic Neoplasms Antibodies  >4 publications with IL17RD and Prostatic Neoplasms
 Gonadal Disorders Antibodies  >1 publications with IL17RD and Gonadal Disorders
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >4 publications with IL17RD and Prostate
 Bone Antibodies  >1 publications with IL17RD and Bone
 Blood Antibodies  >1 publications with IL17RD and Blood
 Heart Antibodies  >1 publications with IL17RD and Heart
 Muscle Antibodies  >1 publications with IL17RD and Muscle
 Intestine Antibodies  >1 publications with IL17RD and Intestine
 Eye Antibodies  >1 publications with IL17RD and Eye
 Kidney Antibodies  >1 publications with IL17RD and Kidney
 Embryonic Tissue Antibodies  >1 publications with IL17RD and Embryonic Tissue
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