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IL21R elisa kit :: Human interleukin 21 receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS917921 IL21R elisa kit
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

interleukin 21 receptor (IL21R), ELISA Kit

 Also Known As   

Human Interleukin-21 receptor, IL21R ELISA Kit

 Product Synonym Names    Human Interleukin-21 receptor (IL21R) ELISA kit; MGC10967; NILR; ; interleukin 21 receptor
 Product Gene Name   

IL21R elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 615207
 3D Structure    ModBase 3D Structure for Q9HBE5
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human IL21R. No significant cross-reactivity or interference between Human IL21R and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL21R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL21R purchase    MBS917921 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interleukin 21 receptor (IL21R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL21R. The ELISA analytical biochemical technique of the MBS917921 kit is based on IL21R antibody-IL21R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL21R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL21R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL21R elisa kit

   For Sample For the quantitative determination of human interleukin-21 receptor (IL21R) concentrations in serum, plasma, tissue homogenates.

PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL21R has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL21R present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL21R is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL21R bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS917921. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL21R. It may not necessarily be applicable to this product.
 NCBI GI #    11141869
 NCBI GeneID    50615
 NCBI Accession #    NP_068570.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021798.3 [Other Products]
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 UniProt Primary Accession #    Q9HBE5 [Other Products]
 UniProt Secondary Accession #    Q96HZ1; Q9HB91; A8K9E8; D3DWF7 [Other Products]
 UniProt Related Accession #    Q9HBE5 [Other Products]
 Molecular Weight    59,130 Da
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 NCBI Official Full Name    interleukin-21 receptor isoform 1
 NCBI Official Synonym Full Names    interleukin 21 receptor
 NCBI Official Symbol    IL21R [Similar Products]
 NCBI Official Synonym Symbols   
NILR; CD360
[Similar Products]
 NCBI Protein Information    interleukin-21 receptor; IL-21 receptor; novel interleukin receptor
 UniProt Protein Name    Interleukin-21 receptor
 UniProt Synonym Protein Names   
Novel interleukin receptor; CD_antigen: CD360
 Protein Family    Interleukin-21 receptor
 UniProt Gene Name    IL21R [Similar Products]
 UniProt Synonym Gene Names    NILR; UNQ3121/PRO10273; IL-21 receptor; IL-21R [Similar Products]
 UniProt Entry Name    IL21R_HUMAN
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 NCBI Summary for IL21R    The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
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 UniProt Comments for IL21R    IL21R: This is a receptor for interleukin-21

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p11

Cellular Component: integral to membrane

Molecular Function: interleukin-21 receptor activity

Biological Process: natural killer cell activation

Disease: Ige Responsiveness, Atopic; Il21r Immunodeficiency
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 Research Articles on IL21R    1. IL-21R gene polymorphisms and serum IL-21 levels predict virological response to interferon-based therapy in Asian chronic hepatitis C patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL21R elisa kitPathways associated with IL21R elisa kit
 Reference Product  PubMed Publications
 JAK1 elisa kit  >11 publications with IL21R and JAK1
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with IL21R elisa kitOrgans/Tissues associated with IL21R elisa kit
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >212 publications with IL21R and Immune System Diseases
 Infection Antibodies  >70 publications with IL21R and Infection
 Hematologic Diseases Antibodies  >28 publications with IL21R and Hematologic Diseases
 IMMUNE SUPPRESSION Antibodies  >19 publications with IL21R and IMMUNE SUPPRESSION
 Lupus Erythematosus, Systemic Antibodies  >17 publications with IL21R and Lupus Erythematosus, Systemic
 Diabetes Mellitus Antibodies  >13 publications with IL21R and Diabetes Mellitus
 Intestinal Diseases Antibodies  >13 publications with IL21R and Intestinal Diseases
 Leukoencephalopathies Antibodies  >11 publications with IL21R and Leukoencephalopathies
 Vascular Diseases Antibodies  >8 publications with IL21R and Vascular Diseases
 Graft vs Host Disease Antibodies  >7 publications with IL21R and Graft vs Host Disease
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >423 publications with IL21R and Blood
 Bone Marrow Antibodies  >67 publications with IL21R and Bone Marrow
 Spleen Antibodies  >51 publications with IL21R and Spleen
 Lymph Node Antibodies  >38 publications with IL21R and Lymph Node
 Liver Antibodies  >35 publications with IL21R and Liver
 Thymus Antibodies  >32 publications with IL21R and Thymus
 Lymph Antibodies  >23 publications with IL21R and Lymph
 Kidney Antibodies  >15 publications with IL21R and Kidney
 Brain Antibodies  >13 publications with IL21R and Brain
 Vascular Antibodies  >11 publications with IL21R and Vascular
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