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IL7R elisa kit :: Human interleukin 7 receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS704684
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

interleukin 7 receptor (IL7R), ELISA Kit

★Popular Item★
 Also Known As   

Human Soluble Interleukin-7 Receptor, sIL-7R ELISA Kit

 Product Synonym Names    Human Soluble Interleukin-7 Receptor; sIL-7R ELISA Kit; CD127; CDW127; IL-7R-alpha; IL7RA; ILRA; CD127 antigen; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; interleukin 7 receptor
 Product Gene Name   

IL7R elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS704684 Testing Data    Testing Data PDF
 OMIM    612595
 3D Structure    ModBase 3D Structure for P16871
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human sIL-7R. No significant cross-reactivity or interference between human sIL-7R and analogues was observed.
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 Samples    serum, plasma, tissue homogenates
 Assay Type    Quantitative Sandwich
 Detection Range    0.78 ng/ml -50 ng/ml
 Sensitivity    <0.195 ng/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL7R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL7R purchase    MBS704684 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interleukin 7 receptor (IL7R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.78 ng/ml -50 ng/ml in biological research samples containing IL7R, with an estimated sensitivity of <0.195 ng/ml. The ELISA analytical biochemical technique of the MBS704684 kit is based on IL7R antibody-IL7R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL7R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL7R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL7R elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for sIL-7R has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any sIL-7R present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for sIL-7R is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of sIL-7R bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of IL7R elisa kit    IL7R elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS704684. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL7R. It may not necessarily be applicable to this product.
 NCBI GI #    28610151
 NCBI GeneID    3575
 NCBI Accession #    NP_002176.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002185.3 [Other Products]
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 UniProt Primary Accession #    P16871 [Other Products]
 UniProt Secondary Accession #    Q05CU8; Q6NSP4; Q6NWM0; Q6NWM1; Q6NWM2; Q6NWM3; Q6SV45; Q9UPC1; B2RCS6; B4DVT1 [Other Products]
 UniProt Related Accession #    P16871 [Other Products]
 Molecular Weight    51,581 Da
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 NCBI Official Full Name    interleukin-7 receptor subunit alpha
 NCBI Official Synonym Full Names    interleukin 7 receptor
 NCBI Official Symbol    IL7R [Similar Products]
 NCBI Official Synonym Symbols   
ILRA; CD127; IL7RA; CDW127; IL-7R-alpha
[Similar Products]
 NCBI Protein Information    interleukin-7 receptor subunit alpha; IL-7RA; CD127 antigen; IL-7R subunit alpha; IL-7 receptor subunit alpha; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6
 UniProt Protein Name    Interleukin-7 receptor subunit alpha
 UniProt Synonym Protein Names   
CDw127; CD_antigen: CD127
 Protein Family    Interleukin-7 receptor
 UniProt Gene Name    IL7R [Similar Products]
 UniProt Synonym Gene Names    IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA [Similar Products]
 UniProt Entry Name    IL7RA_HUMAN
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 NCBI Summary for IL7R    The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2014]
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 UniProt Comments for IL7R    Function: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
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 Research Articles on IL7R    1. we report noncysteine in-frame mutations in IL7R and CRLF2 located in a region of the transmembrane domain closer to the cytosolic domain in acute lymphoblastic leukemias
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL7R elisa kitPathways associated with IL7R elisa kit
 Reference Product  PubMed Publications
 JAK3 elisa kit  >9 publications with IL7R and JAK3
 IL7 elisa kit  >8 publications with IL7R and IL7
 IL2RG elisa kit  >7 publications with IL7R and IL2RG
 JAK1 elisa kit  >3 publications with IL7R and JAK1
 STAT5B elisa kit  >2 publications with IL7R and STAT5B
 CRLF2 elisa kit  >2 publications with IL7R and CRLF2
 FYN elisa kit  >1 publications with IL7R and FYN
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 FoxO Signaling Pathway antibodies  FoxO Signaling Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 IL-7 Signaling Pathway antibodies  IL-7 Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interleukin-7 Signaling Pathway antibodies  Interleukin-7 Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with IL7R elisa kitOrgans/Tissues associated with IL7R elisa kit
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >67 publications with IL7R and Immune System Diseases
 Multiple Sclerosis Antibodies  >28 publications with IL7R and Multiple Sclerosis
 Inflammation Antibodies  >14 publications with IL7R and Inflammation
 Necrosis Antibodies  >10 publications with IL7R and Necrosis
 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Antibodies  >7 publications with IL7R and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
 Disease Models, Animal Antibodies  >6 publications with IL7R and Disease Models, Animal
 Liver Diseases Antibodies  >5 publications with IL7R and Liver Diseases
 Lung Diseases Antibodies  >4 publications with IL7R and Lung Diseases
 Hypersensitivity Antibodies  >4 publications with IL7R and Hypersensitivity
 Encephalomyelitis, Autoimmune, Experimental Antibodies  >3 publications with IL7R and Encephalomyelitis, Autoimmune, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >51 publications with IL7R and Blood
 Bone Antibodies  >10 publications with IL7R and Bone
 Thymus Antibodies  >10 publications with IL7R and Thymus
 Brain Antibodies  >4 publications with IL7R and Brain
 Liver Antibodies  >4 publications with IL7R and Liver
 Kidney Antibodies  >4 publications with IL7R and Kidney
 Lymph Node Antibodies  >3 publications with IL7R and Lymph Node
 Skin Antibodies  >3 publications with IL7R and Skin
 Intestine Antibodies  >3 publications with IL7R and Intestine
 Lung Antibodies  >3 publications with IL7R and Lung
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