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IRX3 elisa kit :: Human iroquois homeobox 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9335489 IRX3 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

iroquois homeobox 3 (IRX3), ELISA Kit

 Also Known As   

Human Iroquois-class homeodomain protein IRX-3, IRX3 ELISA Kit

 Product Synonym Names    Human Iroquois-class homeodomain protein IRX-3 (IRX3) ELISA kit; FLJ99187; IRX-1; IRXB1; homeodomain protein IRXB1; iroquois homeobox protein 3; iroquois-class homeodomain protein IRX-1; iroquois homeobox 3
 Product Gene Name   

IRX3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    612985
 3D Structure    ModBase 3D Structure for P78415
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IRX3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IRX3 purchase    MBS9335489 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the iroquois homeobox 3 (IRX3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IRX3. The ELISA analytical biochemical technique of the MBS9335489 kit is based on IRX3 antibody-IRX3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IRX3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IRX3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IRX3. It may not necessarily be applicable to this product.
 NCBI GI #    226371735
 NCBI GeneID    79191
 NCBI Accession #    NP_077312.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_024336.2 [Other Products]
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 UniProt Primary Accession #    P78415 [Other Products]
 UniProt Secondary Accession #    Q7Z4A4; Q7Z4A5; Q8IVC6 [Other Products]
 UniProt Related Accession #    P78415 [Other Products]
 Molecular Weight    52,119 Da
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 NCBI Official Full Name    iroquois-class homeodomain protein IRX-3
 NCBI Official Synonym Full Names    iroquois homeobox 3
 NCBI Official Symbol    IRX3 [Similar Products]
 NCBI Official Synonym Symbols   
IRX-1; IRXB1
[Similar Products]
 NCBI Protein Information    iroquois-class homeodomain protein IRX-3; homeodomain protein IRXB1; iroquois homeobox protein 3; iroquois-class homeodomain protein IRX-1
 UniProt Protein Name    Iroquois-class homeodomain protein IRX-3
 UniProt Synonym Protein Names   
Homeodomain protein IRXB1; Iroquois homeobox protein 3
 Protein Family    Iroquois-class homeodomain protein
 UniProt Gene Name    IRX3 [Similar Products]
 UniProt Synonym Gene Names    IRXB1 [Similar Products]
 UniProt Entry Name    IRX3_HUMAN
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 NCBI Summary for IRX3    IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009]
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 UniProt Comments for IRX3    IRX3: Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Belongs to the TALE/IRO homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 16q12.2

Cellular Component: axon; cytoplasm; nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: negative regulation of neuron differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; mesoderm development; positive regulation of neuron differentiation; metanephros development
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 Research Articles on IRX3    1. data suggest that IRX3 is a functional long-range target of obesity-associated variants within FTO and represents a novel determinant of body mass and composition
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IRX3 elisa kitDiseases associated with IRX3 elisa kit
 Reference Product  PubMed Publications
 IRX5 elisa kit  >17 publications with IRX3 and IRX5
 SHH elisa kit  >7 publications with IRX3 and SHH
 NKX2-2 elisa kit  >5 publications with IRX3 and NKX2-2
 DBX2 elisa kit  >2 publications with IRX3 and DBX2
 OLIG2 elisa kit  >2 publications with IRX3 and OLIG2
 DBX1 elisa kit  >1 publications with IRX3 and DBX1
 Disease Name  Pubmed Publications
 Eye Diseases Antibodies  >7 publications with IRX3 and Eye Diseases
 Adenocarcinoma Antibodies  >3 publications with IRX3 and Adenocarcinoma
 Breast Neoplasms Antibodies  >2 publications with IRX3 and Breast Neoplasms
 Weight Loss Antibodies  >2 publications with IRX3 and Weight Loss
 Ovarian Diseases Antibodies  >1 publications with IRX3 and Ovarian Diseases
 Heart Diseases Antibodies  >1 publications with IRX3 and Heart Diseases
 Mammary Neoplasms, Animal Antibodies  >1 publications with IRX3 and Mammary Neoplasms, Animal
 Insulin Resistance Antibodies  >1 publications with IRX3 and Insulin Resistance
 Kidney Diseases Antibodies  >1 publications with IRX3 and Kidney Diseases
 Disease Models, Animal Antibodies  >1 publications with IRX3 and Disease Models, Animal
Organs/Tissues associated with IRX3 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with IRX3 and Brain
 Eye Antibodies  >11 publications with IRX3 and Eye
 Embryonic Tissue Antibodies  >10 publications with IRX3 and Embryonic Tissue
 Heart Antibodies  >7 publications with IRX3 and Heart
 Kidney Antibodies  >4 publications with IRX3 and Kidney
 Muscle Antibodies  >3 publications with IRX3 and Muscle
 Blood Antibodies  >3 publications with IRX3 and Blood
 Salivary Gland Antibodies  >2 publications with IRX3 and Salivary Gland
 Testis Antibodies  >2 publications with IRX3 and Testis
 Liver Antibodies  >1 publications with IRX3 and Liver
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