Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow IAPP rightarrow Human IAPP  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • ANKRA2 Antibody
 • Albumin Standard Ampules (5mg-ml BSA) Protein Standard
 • Activating Transcription Factor 1 (ATF1) ELISA Kit
 • 1-Desamino 8D Arginine Vasopressin (DDAVP) Antibody
 • Cytokeratin 8 & 18 (KRT8) Antibody
 • Interleukin 1 Receptor Associated Kinase 4 (IRAK4) ELISA Kit
 • VAX2 Antibody
 • fms-related tyrosine kinase 4 (FLT4) ELISA Kit
 • Vimentin Antibody
 • Immunoglobulin G3 (IgG3) Antibody
 • toll-like receptor 4 (TLR4) ELISA Kit
 • DOCK2 cDNA Clone
 • Integrin alpha 1 (ITGA1) Antibody
 • Interleukin 1A (IL-1A) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

IAPP elisa kit :: Human islet amyloid polypeptide ELISA Kit

Scan QR to view Datasheet Catalog #    MBS702315
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

islet amyloid polypeptide (IAPP), ELISA Kit

★Popular Item★
 Also Known As   

Human islet amyloid polypeptide, IAPP ELISA Kit

 Product Synonym Names    Human islet amyloid polypeptide; IAPP ELISA Kit; AMYLIN; DAP; IAP; Islet amyloid polypeptide (diabetes-associated peptide; amylin) ; islet amyloid polypeptide
 Product Gene Name   

IAPP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS702315 Testing Data    Testing Data PDF
 OMIM    147940
 3D Structure    ModBase 3D Structure for P10997
Section Bar
 Species Reactivity    Human
Section Bar
 Specificity    This assay has high sensitivity and excellent specificity for detection of human IAPP. No significant cross-reactivity or interference between human IAPP and analogues was observed.
Section Bar
 Samples    Serum, plasma, urine
 Assay Type    Quantitative Sandwich
 Detection Range    47 pg/ml -3000 pg/ml
 Sensitivity    Typically less than 11.75 pg/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Section Bar
 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IAPP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IAPP purchase    MBS702315 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the islet amyloid polypeptide (IAPP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 47 pg/ml -3000 pg/ml in biological research samples containing IAPP, with an estimated sensitivity of Typically less than 11.75 pg/ml. The ELISA analytical biochemical technique of the MBS702315 kit is based on IAPP antibody-IAPP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IAPP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IAPP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, urine. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Related Product Information for IAPP elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IAPP has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IAPP present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IAPP is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IAPP bound in the initial step. The color development is stopped and the intensity of the color is measured.
Section Bar
 Typical Testing Data/Standard Curve (for reference only) of IAPP elisa kit    IAPP elisa kit Typical Testing Data/Standard Curve (for reference only) image
Table BarTOPTable Bar
Sample Manual Insert of MBS702315. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for IAPP. It may not necessarily be applicable to this product.
 NCBI GI #    4557655
 NCBI GeneID    3375
 NCBI Accession #    NP_000406.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000415.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P10997 [Other Products]
 UniProt Secondary Accession #    Q0ZD87; Q14598 [Other Products]
 UniProt Related Accession #    P10997 [Other Products]
 Molecular Weight    9,806 Da
Table BarTOPTable Bar
 NCBI Official Full Name    islet amyloid polypeptide
 NCBI Official Synonym Full Names    islet amyloid polypeptide
 NCBI Official Symbol    IAPP [Similar Products]
 NCBI Official Synonym Symbols   
DAP; IAP
[Similar Products]
 NCBI Protein Information    islet amyloid polypeptide; amylin; insulinoma amyloid peptide; diabetes-associated peptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin)
 UniProt Protein Name    Islet amyloid polypeptide
 UniProt Synonym Protein Names   
Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide
 Protein Family    Islet amyloid polypeptide
 UniProt Gene Name    IAPP [Similar Products]
 UniProt Synonym Gene Names    DAP [Similar Products]
 UniProt Entry Name    IAPP_HUMAN
Section Bar
 NCBI Summary for IAPP    Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq, Apr 2011]
Section Bar
 UniProt Comments for IAPP    Function: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
Table BarTOPTable Bar
 Research Articles on IAPP    1. C-peptide-insulin and IAPP-insulin interactions are mediated by a defined binding site, while such a feature is not apparent in the IAPP-C-peptide association.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with IAPP elisa kitPathways associated with IAPP elisa kit
 Reference Product  PubMed Publications
 INS elisa kit  >40 publications with IAPP and INS
 SCT elisa kit  >30 publications with IAPP and SCT
 RAMP3 elisa kit  >18 publications with IAPP and RAMP3
 TTR elisa kit  >4 publications with IAPP and TTR
 ADM elisa kit  >3 publications with IAPP and ADM
 GCG elisa kit  >3 publications with IAPP and GCG
 CALCR elisa kit  >2 publications with IAPP and CALCR
 CALCA elisa kit  >1 publications with IAPP and CALCA
 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Calcitonin-like Ligand Receptors Pathway antibodies  Calcitonin-like Ligand Receptors Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Maturity Onset Diabetes Of The Young Pathway antibodies  Maturity Onset Diabetes Of The Young Pathway Diagram
Diseases associated with IAPP elisa kitOrgans/Tissues associated with IAPP elisa kit
 Disease Name  Pubmed Publications
 Diabetes Mellitus Antibodies  >899 publications with IAPP and Diabetes Mellitus
 Diabetes Mellitus, Type 2 Antibodies  >585 publications with IAPP and Diabetes Mellitus, Type 2
 Insulin Resistance Antibodies  >210 publications with IAPP and Insulin Resistance
 Hyperglycemia Antibodies  >170 publications with IAPP and Hyperglycemia
 Hyperinsulinism Antibodies  >118 publications with IAPP and Hyperinsulinism
 Disease Models, Animal Antibodies  >113 publications with IAPP and Disease Models, Animal
 Diabetes Mellitus, Experimental Antibodies  >86 publications with IAPP and Diabetes Mellitus, Experimental
 Inflammation Antibodies  >41 publications with IAPP and Inflammation
 Hypertension Antibodies  >34 publications with IAPP and Hypertension
 Kidney Diseases Antibodies  >19 publications with IAPP and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >711 publications with IAPP and Pancreas
 Connective Tissue Antibodies  >37 publications with IAPP and Connective Tissue
 Mixed Antibodies  >32 publications with IAPP and Mixed
 Testis Antibodies  >1 publications with IAPP and Testis
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions