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KRT85 elisa kit :: Human keratin 85 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9322578 KRT85 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

keratin 85 (KRT85), ELISA Kit

 Also Known As   

Human Keratin, type II cuticular Hb5, KRT85 ELISA Kit

 Product Synonym Names    Human Keratin; type II cuticular Hb5 (KRT85) ELISA kit; HB5; Hb-5; KRTHB5; hHb5; hard keratin; type II; 5; keratin; hair; basic; 5; keratin 85
 Product Gene Name   

KRT85 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    602767
 3D Structure    ModBase 3D Structure for P78386
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of KRT85 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for KRT85 purchase    MBS9322578 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the keratin 85 (KRT85) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KRT85. The ELISA analytical biochemical technique of the MBS9322578 kit is based on KRT85 antibody-KRT85 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KRT85 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KRT85. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for KRT85. It may not necessarily be applicable to this product.
 NCBI GI #    4504935
 NCBI GeneID    3891
 NCBI Accession #    NP_002274.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002283.3 [Other Products]
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 UniProt Primary Accession #    P78386 [Other Products]
 UniProt Secondary Accession #    Q9NSB1 [Other Products]
 UniProt Related Accession #    P78386 [Other Products]
 Molecular Weight    55,802 Da
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 NCBI Official Full Name    keratin, type II cuticular Hb5 isoform 1
 NCBI Official Synonym Full Names    keratin 85
 NCBI Official Symbol    KRT85 [Similar Products]
 NCBI Official Synonym Symbols   
HB5; K85; Hb-5; hHb5; ECTD4; KRTHB5
[Similar Products]
 NCBI Protein Information    keratin, type II cuticular Hb5; keratin-85; hair keratin K2.12; type-II keratin Kb25; keratin, hair, basic, 5; hard keratin, type II, 5; type II hair keratin Hb5
 UniProt Protein Name    Keratin, type II cuticular Hb5
 UniProt Synonym Protein Names   
Hair keratin K2.12; Keratin-85; K85; Type II hair keratin Hb5; Type-II keratin Kb25
 Protein Family    Keratin
 UniProt Gene Name    KRT85 [Similar Products]
 UniProt Synonym Gene Names    KRTHB5; K85 [Similar Products]
 UniProt Entry Name    KRT85_HUMAN
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 NCBI Summary for KRT85    The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. [provided by RefSeq, Jul 2008]
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 UniProt Comments for KRT85    K85: Defects in KRT85 are the cause of ectodermal dysplasia pure hair-nail type (EDPHN). Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EDPHN is characterized by complete alopecia, hypotricosis and nail dystrophy in all digits. There is no evidence of any other abnormality. Inheritance can be autosomal dominant or recessive. Belongs to the intermediate filament family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: extracellular space; keratin filament

Molecular Function: structural molecule activity

Biological Process: epidermis development

Disease: Ectodermal Dysplasia 4, Hair/nail Type
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 Research Articles on KRT85    1. Our study confirms linkage of a variant clinical form of hair-nail ectodermal dysplasia to chromosome 12 without any mutation in the coding sequences of the KRTHB5 gene.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with KRT85 elisa kit
 Disease Name  Pubmed Publications
 ECTODERMAL DYSPLASIA, 'PURE' HAIR-NAIL TYPE Antibodies  >2 publications with KRT85 and ECTODERMAL DYSPLASIA, 'PURE' HAIR-NAIL TYPE
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