NP_001007103.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
88,337 Da
NCBI Official Full Name
lethal(3)malignant brain tumor-like protein 3 isoform b
NCBI Official Synonym Full Names
l(3)mbt-like 3 (Drosophila)
NCBI Official Synonym Symbols
NCBI Protein Information
lethal(3)malignant brain tumor-like protein 3; lethal(3)malignant brain tumor-like protein 3; l(3)mbt-like protein 3; H-l(3)mbt-like protein 3
UniProt Protein Name
Lethal(3)malignant brain tumor-like protein 3
UniProt Synonym Protein Names
MBT-1
UniProt Synonym Gene Names
KIAA1798; MBT1; H-l(3)mbt-like protein 3; L(3)mbt-like protein 3 [Similar Products]
UniProt Entry Name
LMBL3_HUMAN
UniProt Comments for L3MBTL3
L3MBTL3: a Polycomb group (PcG) protein that regulates the maturation of myeloid progenitor cells. May influence myelopoiesis by transiently enhancing p57(KIP2) expression levels. PcG proteins participate in DNA-binding complexes with gene-repressing activity, many of which have been highlighted for their involvement in hematopoiesis. A member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. Contains a SAM domain, a common protein modules found in eukaryotic proteomes. Many SAM domains have been shown to form helical polymer structures. May create large protein complexes in the cell. Two isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 6q23
Cellular Component: nucleus
Biological Process: erythrocyte maturation; macrophage differentiation; granulocyte differentiation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; chromatin modification
Research Articles on L3MBTL3
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Diseases associated with L3MBTL3 elisa kit
Organs/Tissues associated with L3MBTL3 elisa kit
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