NP_005550.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
337,084 Da
NCBI Official Full Name
laminin subunit alpha-1
NCBI Official Synonym Full Names
laminin, alpha 1
NCBI Protein Information
laminin subunit alpha-1; S-LAM alpha; laminin A chain; S-laminin subunit alpha; laminin-3 subunit alpha
UniProt Protein Name
Laminin subunit alpha-1
UniProt Synonym Protein Names
Laminin A chain; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-laminin subunit alpha; S-LAM alpha
UniProt Synonym Gene Names
UniProt Entry Name
LAMA1_HUMAN
NCBI Summary for LAMA1
This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]
UniProt Comments for LAMA1
LAMA1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Extracellular matrix; Secreted
Chromosomal Location of Human Ortholog: 18p11.3
Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; laminin-3 complex; laminin-1 complex; extracellular region; basement membrane; intercellular junction
Molecular Function: protein binding; extracellular matrix structural constituent; glycosphingolipid binding; receptor binding
Biological Process: regulation of cell adhesion; axon guidance; extracellular matrix organization and biogenesis; cell surface receptor linked signal transduction; regulation of embryonic development; morphogenesis of an epithelial sheet; establishment of epithelial cell polarity; cell adhesion; regulation of cell migration
Disease: Poretti-boltshauser Syndrome
Research Articles on LAMA1
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Pathways associated with LAMA1 elisa kit
Diseases associated with LAMA1 elisa kit
Organs/Tissues associated with LAMA1 elisa kit
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