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LAMB3 elisa kit :: Human laminin, beta 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9318129 LAMB3 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

laminin, beta 3 (LAMB3), ELISA Kit

★Popular Item★
 Also Known As   

Human Laminin subunit beta-3, LAMB3 ELISA Kit

 Product Synonym Names    Human Laminin subunit beta-3 (LAMB3) ELISA kit; RP1-272L16.3; BM600-125KDA; FLJ99565; LAM5; LAMNB1; kalinin B1 chain; kalinin-140kDa; laminin B1k chain; laminin S B3 chain; laminin; beta 3 (nicein (125kD); kalinin (140kD); BM600 (125kD) ) ; nicein-125kD; laminin; beta 3
 Product Gene Name   

LAMB3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    226700
 3D Structure    ModBase 3D Structure for Q13751
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
 Assay Type    Sandwich
 Detection Range    3.12 ug/ml - 100 ug/ml.
 Sensitivity    1.0 ug/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LAMB3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LAMB3 purchase    MBS9318129 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the laminin, beta 3 (LAMB3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.12 ug/ml - 100 ug/ml in biological research samples containing LAMB3, with an estimated sensitivity of 1.0 ug/ml. The ELISA analytical biochemical technique of the MBS9318129 kit is based on LAMB3 antibody-LAMB3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LAMB3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LAMB3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for LAMB3 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LAMB3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9318129. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LAMB3. It may not necessarily be applicable to this product.
 NCBI GI #    62868215
 NCBI GeneID    3914
 NCBI Accession #    NP_000219.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000228.2 [Other Products]
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 UniProt Primary Accession #    Q13751 [Other Products]
 UniProt Secondary Accession #    O14947; Q14733; Q9UJK4; Q9UJL1; D3DT88 [Other Products]
 UniProt Related Accession #    Q13751 [Other Products]
 Molecular Weight    129,572 Da
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 NCBI Official Full Name    laminin subunit beta-3
 NCBI Official Synonym Full Names    laminin, beta 3
 NCBI Official Symbol    LAMB3 [Similar Products]
 NCBI Official Synonym Symbols   
LAM5; LAMNB1; BM600-125KDA
[Similar Products]
 NCBI Protein Information    laminin subunit beta-3; nicein-125kDa; kalinin-140kDa; kalinin B1 chain; laminin B1k chain; laminin S B3 chain; nicein subunit beta; kalinin subunit beta; epiligrin subunit bata; laminin-5 subunit beta; laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD))
 UniProt Protein Name    Laminin subunit beta-3
 UniProt Synonym Protein Names   
Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin-5 subunit beta; Nicein subunit beta
 Protein Family    Laminin
 UniProt Gene Name    LAMB3 [Similar Products]
 UniProt Synonym Gene Names    LAMNB1 [Similar Products]
 UniProt Entry Name    LAMB3_HUMAN
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 NCBI Summary for LAMB3    The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LAMB3    LAMB3: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Defects in LAMB3 are a cause of epidermolysis bullosa junctional Herlitz type (H-JEB); also known as junctional epidermolysis bullosa Herlitz-Pearson type. JEB defines a group of blistering skin diseases characterized by tissue separation which occurs within the dermo-epidermal basement membrane. H-JEB is a severe, infantile and lethal form. Death occurs usually within the first six months of life. Occasionally, children survive to teens. H-JEB is marked by bullous lesions at birth and extensive denudation of skin and mucous membranes that may be hemorrhagic. Defects in LAMB3 are a cause of generalized atrophic benign epidermolysis bullosa (GABEB). GABEB is a non- lethal, adult form of junctional epidermolysis bullosa characterized by life-long blistering of the skin, associated with hair and tooth abnormalities.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: laminin-5 complex; extracellular region

Molecular Function: protein binding; protein complex binding; structural molecule activity

Biological Process: extracellular matrix disassembly; hemidesmosome assembly; extracellular matrix organization and biogenesis; epidermis development; brown fat cell differentiation; cell adhesion

Disease: Epidermolysis Bullosa, Junctional, Non-herlitz Type; Epidermolysis Bullosa, Junctional, Herlitz Type; Amelogenesis Imperfecta, Type Ia
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 Research Articles on LAMB3    1. data further enhance the mutation spectrum of the LAMB3 and the COL7A1 genes, and also underscore the crucial roles of these genes in pathogenesis of epidermolysis bullosa
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LAMB3 elisa kitPathways associated with LAMB3 elisa kit
 Reference Product  PubMed Publications
 LAMC2 elisa kit  >48 publications with LAMB3 and LAMC2
 LAMA3 elisa kit  >47 publications with LAMB3 and LAMA3
 COL7A1 elisa kit  >4 publications with LAMB3 and COL7A1
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
Diseases associated with LAMB3 elisa kitOrgans/Tissues associated with LAMB3 elisa kit
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >83 publications with LAMB3 and Skin Diseases
 Epidermolysis Bullosa, Junctional Antibodies  >82 publications with LAMB3 and Epidermolysis Bullosa, Junctional
 Neoplasms Antibodies  >19 publications with LAMB3 and Neoplasms
 Carcinoma Antibodies  >12 publications with LAMB3 and Carcinoma
 Neoplasm Metastasis Antibodies  >5 publications with LAMB3 and Neoplasm Metastasis
 Carcinoma, Squamous Cell Antibodies  >5 publications with LAMB3 and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >3 publications with LAMB3 and Lung Neoplasms
 Necrosis Antibodies  >3 publications with LAMB3 and Necrosis
 Anemia Antibodies  >2 publications with LAMB3 and Anemia
 Inflammation Antibodies  >2 publications with LAMB3 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >64 publications with LAMB3 and Skin
 Blood Antibodies  >6 publications with LAMB3 and Blood
 Prostate Antibodies  >4 publications with LAMB3 and Prostate
 Lung Antibodies  >4 publications with LAMB3 and Lung
 Mouth Antibodies  >3 publications with LAMB3 and Mouth
 Stomach Antibodies  >3 publications with LAMB3 and Stomach
 Bladder Antibodies  >2 publications with LAMB3 and Bladder
 Amniotic Fluid Antibodies  >2 publications with LAMB3 and Amniotic Fluid
 Intestine Antibodies  >2 publications with LAMB3 and Intestine
 Eye Antibodies  >2 publications with LAMB3 and Eye
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