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LTBP1 elisa kit :: Human latent transforming growth factor beta binding protein 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS933281 LTBP1 elisa kit
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

latent transforming growth factor beta binding protein 1 (LTBP1), ELISA Kit

★Popular Item★
 Also Known As   

Human Latent-transforming growth factor beta-binding protein 1, LTBP1 ELISA Kit

 Product Synonym Names    Human Latent-transforming growth factor beta-binding protein 1 (LTBP1) ELISA kit; MGC163161; TGF-beta1-BP-1; latent-transforming growth factor beta-binding protein 1; transforming growth factor beta-1-binding protein 1; latent transforming growth factor beta binding protein 1
 Product Gene Name   

LTBP1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    150390
 3D Structure    ModBase 3D Structure for Q14766
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human LTBP1. No significant cross-reactivity or interference between human LTBP1 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Detection Range    0.156 ng/ml -10 ng/mL
 Sensitivity    <0.039 ng/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LTBP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LTBP1 purchase    MBS933281 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the latent transforming growth factor beta binding protein 1 (LTBP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156 ng/ml -10 ng/mL in biological research samples containing LTBP1, with an estimated sensitivity of <0.039 ng/mL. The ELISA analytical biochemical technique of the MBS933281 kit is based on LTBP1 antibody-LTBP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LTBP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LTBP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for LTBP1 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for LTBP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LTBP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LTBP1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LTBP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS933281. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LTBP1. It may not necessarily be applicable to this product.
 NCBI GI #    261337167
 NCBI GeneID    4052
 NCBI Accession #    NP_000618.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000627.3 [Other Products]
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 UniProt Primary Accession #    Q14766 [Other Products]
 UniProt Secondary Accession #    P22064; Q53SD8; Q53SF3; Q53SG1; Q59HF7; Q8TD95; A1L3V1 [Other Products]
 UniProt Related Accession #    Q14766 [Other Products]
 Molecular Weight    186,796 Da
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 NCBI Official Full Name    latent-transforming growth factor beta-binding protein 1 isoform LTBP-1S
 NCBI Official Synonym Full Names    latent transforming growth factor beta binding protein 1
 NCBI Official Symbol    LTBP1 [Similar Products]
 NCBI Protein Information    latent-transforming growth factor beta-binding protein 1; LTBP-1; TGF-beta1-BP-1; transforming growth factor beta-1-binding protein 1
 UniProt Protein Name    Latent-transforming growth factor beta-binding protein 1
 UniProt Synonym Protein Names   
Transforming growth factor beta-1-binding protein 1; TGF-beta1-BP-1
 Protein Family    Latent-transforming growth factor beta-binding protein
 UniProt Gene Name    LTBP1 [Similar Products]
 UniProt Synonym Gene Names    LTBP-1; TGF-beta1-BP-1 [Similar Products]
 UniProt Entry Name    LTBP1_HUMAN
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 NCBI Summary for LTBP1    The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LTBP1    LTBP1: May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). Belongs to the LTBP family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2p22-p21

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; protein complex; microfibril; extracellular region

Molecular Function: transforming growth factor beta receptor activity; protein binding; transforming growth factor beta binding; microfibril binding; calcium ion binding

Biological Process: extracellular matrix organization and biogenesis; transmembrane receptor protein serine/threonine kinase signaling pathway
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 Research Articles on LTBP1    1. these results suggested that the C allele could increase TGF-beta secretion which suppresses antitumour immune responses and may affect the Oral squamous cell carcinoma risk.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LTBP1 elisa kitPathways associated with LTBP1 elisa kit
 Reference Product  PubMed Publications
 TGFB1 elisa kit  >46 publications with LTBP1 and TGFB1
 TGFB2 elisa kit  >12 publications with LTBP1 and TGFB2
 TGFB3 elisa kit  >6 publications with LTBP1 and TGFB3
 AHR elisa kit  >5 publications with LTBP1 and AHR
 THBS1 elisa kit  >3 publications with LTBP1 and THBS1
 Products by Pathway  Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Molecules Associated With Elastic Fibres Pathway antibodies  Molecules Associated With Elastic Fibres Pathway Diagram
 TGF Beta Signaling Pathway antibodies  TGF Beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
Diseases associated with LTBP1 elisa kitOrgans/Tissues associated with LTBP1 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >17 publications with LTBP1 and Cardiovascular Diseases
 Heart Diseases Antibodies  >10 publications with LTBP1 and Heart Diseases
 Congenital Abnormalities Antibodies  >9 publications with LTBP1 and Congenital Abnormalities
 Heart Defects, Congenital Antibodies  >5 publications with LTBP1 and Heart Defects, Congenital
 Disease Models, Animal Antibodies  >5 publications with LTBP1 and Disease Models, Animal
 Liver Diseases Antibodies  >5 publications with LTBP1 and Liver Diseases
 Breast Neoplasms Antibodies  >4 publications with LTBP1 and Breast Neoplasms
 Adenocarcinoma Antibodies  >4 publications with LTBP1 and Adenocarcinoma
 Kidney Diseases Antibodies  >4 publications with LTBP1 and Kidney Diseases
 Ovarian Neoplasms Antibodies  >3 publications with LTBP1 and Ovarian Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >19 publications with LTBP1 and Bone
 Vascular Antibodies  >18 publications with LTBP1 and Vascular
 Connective Tissue Antibodies  >15 publications with LTBP1 and Connective Tissue
 Lung Antibodies  >14 publications with LTBP1 and Lung
 Muscle Antibodies  >12 publications with LTBP1 and Muscle
 Heart Antibodies  >11 publications with LTBP1 and Heart
 Skin Antibodies  >10 publications with LTBP1 and Skin
 Kidney Antibodies  >10 publications with LTBP1 and Kidney
 Embryonic Tissue Antibodies  >10 publications with LTBP1 and Embryonic Tissue
 Liver Antibodies  >7 publications with LTBP1 and Liver
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