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LTBP3 elisa kit :: Human latent transforming growth factor beta binding protein 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS920015 LTBP3 elisa kit
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

latent transforming growth factor beta binding protein 3 (LTBP3), ELISA Kit

 Also Known As   

Human Latent-transforming growth factor beta-binding protein 3, LTBP3 ELISA Kit

 Product Synonym Names    Human Latent-transforming growth factor beta-binding protein 3 (LTBP3) ELISA kit; DKFZp586M2123; FLJ33431; FLJ39893; FLJ42533; FLJ44138; FLJ45576; LTBP-3; LTBP2; STHAG6; pp6425; latent TGF beta binding protein 3; latent transforming growth factor beta binding protein 3
 Product Gene Name   

LTBP3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 613097
 3D Structure    ModBase 3D Structure for Q9NS15
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human LTBP3. No significant cross-reactivity or interference between Human LTBP3 and analogues was observed.
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 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LTBP3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LTBP3 purchase    MBS920015 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the latent transforming growth factor beta binding protein 3 (LTBP3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LTBP3. The ELISA analytical biochemical technique of the MBS920015 kit is based on LTBP3 antibody-LTBP3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LTBP3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LTBP3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for LTBP3. It may not necessarily be applicable to this product.
 NCBI GI #    194328809
 NCBI GeneID    4054
 NCBI Accession #    NP_001123616.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001130144.2 [Other Products]
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 UniProt Primary Accession #    Q9NS15 [Other Products]
 UniProt Secondary Accession #    O15107; Q96HB9; Q9H7K2; Q9UFN4 [Other Products]
 UniProt Related Accession #    Q9NS15 [Other Products]
 Molecular Weight    139,359 Da
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 NCBI Official Full Name    latent-transforming growth factor beta-binding protein 3 isoform 1
 NCBI Official Synonym Full Names    latent transforming growth factor beta binding protein 3
 NCBI Official Symbol    LTBP3 [Similar Products]
 NCBI Official Synonym Symbols   
LTBP2; LTBP-3; STHAG6; pp6425
[Similar Products]
 NCBI Protein Information    latent-transforming growth factor beta-binding protein 3; latent TGF beta binding protein 3
 UniProt Protein Name    Latent-transforming growth factor beta-binding protein 3
 Protein Family    Latent-transforming growth factor beta-binding protein
 UniProt Gene Name    LTBP3 [Similar Products]
 UniProt Synonym Gene Names    LTBP-3 [Similar Products]
 UniProt Entry Name    LTBP3_HUMAN
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 NCBI Summary for LTBP3    The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
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 UniProt Comments for LTBP3    LTBP3: May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). Defects in LTBP3 are the cause of tooth agenesis selective type 6 (STHAG6). A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth). Some individuals affected by tooth agenesis selective type 6 have short stature. Belongs to the LTBP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Extracellular matrix

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: extracellular matrix; extracellular region

Molecular Function: transforming growth factor beta binding; calcium ion binding

Biological Process: negative regulation of bone mineralization; extracellular matrix organization and biogenesis; transforming growth factor beta receptor signaling pathway; negative regulation of chondrocyte differentiation; positive regulation of bone resorption; bone remodeling

Disease: Tooth Agenesis, Selective, 6; Dental Anomalies And Short Stature
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 Research Articles on LTBP3    1. Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LTBP3 elisa kitPathways associated with LTBP3 elisa kit
 Reference Product  PubMed Publications
 TGFB1 elisa kit  >6 publications with LTBP3 and TGFB1
 TGFB2 elisa kit  >1 publications with LTBP3 and TGFB2
 TGFB3 elisa kit  >1 publications with LTBP3 and TGFB3
 MSTN elisa kit  >1 publications with LTBP3 and MSTN
 Products by Pathway  Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Molecules Associated With Elastic Fibres Pathway antibodies  Molecules Associated With Elastic Fibres Pathway Diagram
Diseases associated with LTBP3 elisa kitOrgans/Tissues associated with LTBP3 elisa kit
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >5 publications with LTBP3 and Congenital Abnormalities
 Osteosclerosis Antibodies  >3 publications with LTBP3 and Osteosclerosis
 Carcinoma Antibodies  >3 publications with LTBP3 and Carcinoma
 Craniofacial Abnormalities Antibodies  >3 publications with LTBP3 and Craniofacial Abnormalities
 Liver Diseases Antibodies  >2 publications with LTBP3 and Liver Diseases
 Fibrosis Antibodies  >2 publications with LTBP3 and Fibrosis
 Osteoarthritis Antibodies  >2 publications with LTBP3 and Osteoarthritis
 Kyphosis Antibodies  >2 publications with LTBP3 and Kyphosis
 Liver Neoplasms Antibodies  >1 publications with LTBP3 and Liver Neoplasms
 Breast Neoplasms Antibodies  >1 publications with LTBP3 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >10 publications with LTBP3 and Bone
 Lung Antibodies  >6 publications with LTBP3 and Lung
 Connective Tissue Antibodies  >5 publications with LTBP3 and Connective Tissue
 Muscle Antibodies  >5 publications with LTBP3 and Muscle
 Blood Antibodies  >4 publications with LTBP3 and Blood
 Embryonic Tissue Antibodies  >2 publications with LTBP3 and Embryonic Tissue
 Heart Antibodies  >2 publications with LTBP3 and Heart
 Brain Antibodies  >2 publications with LTBP3 and Brain
 Vascular Antibodies  >1 publications with LTBP3 and Vascular
 Ovary Antibodies  >1 publications with LTBP3 and Ovary
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