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LRIG1 elisa kit :: Human leucine-rich repeats and immunoglobulin-like domains 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS908302
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1), ELISA Kit

★Popular Item★
 Also Known As   

Human Leucine-rich repeats and immunoglobulin-like domains protein 1, LRIG1 ELISA Kit

 Product Synonym Names    Human Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) ELISA kit; DKFZp586O1624; LIG-1; LIG1; leucine-rich repeat protein LRIG1; ortholog of mouse integral membrane glycoprotein LIG-1; leucine-rich repeats and immunoglobulin-like domains 1
 Product Gene Name   

LRIG1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS908302 Testing Data    Testing Data PDF
 OMIM    608868
 3D Structure    ModBase 3D Structure for Q96JA1
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human LRIG1. No significant cross-reactivity or interference between Human LRIG1 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    0.156 ng/ml-10 ng/ml
 Sensitivity    0.039 ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LRIG1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LRIG1 purchase    MBS908302 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156 ng/ml-10 ng/ml in biological research samples containing LRIG1, with an estimated sensitivity of 0.039 ng/ml. The ELISA analytical biochemical technique of the MBS908302 kit is based on LRIG1 antibody-LRIG1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LRIG1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LRIG1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for LRIG1 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for LRIG1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LRIG1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LRIG1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LRIG1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of LRIG1 elisa kit    LRIG1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS908302. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LRIG1. It may not necessarily be applicable to this product.
 NCBI GI #    54607118
 NCBI GeneID    26018
 NCBI Accession #    NP_056356.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_015541.2 [Other Products]
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 UniProt Primary Accession #    Q96JA1 [Other Products]
 UniProt Secondary Accession #    Q6IQ51; Q96CF9; Q9BYB8; Q9UFI4 [Other Products]
 UniProt Related Accession #    Q96JA1 [Other Products]
 Molecular Weight    119,113 Da
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 NCBI Official Full Name    leucine-rich repeats and immunoglobulin-like domains protein 1
 NCBI Official Synonym Full Names    leucine-rich repeats and immunoglobulin-like domains 1
 NCBI Official Symbol    LRIG1 [Similar Products]
 NCBI Official Synonym Symbols   
LIG1; LIG-1
[Similar Products]
 NCBI Protein Information    leucine-rich repeats and immunoglobulin-like domains protein 1; leucine-rich repeat protein LRIG1; ortholog of mouse integral membrane glycoprotein LIG-1
 UniProt Protein Name    Leucine-rich repeats and immunoglobulin-like domains protein 1
 Protein Family    Leucine-rich repeats and immunoglobulin-like domains protein
 UniProt Gene Name    LRIG1 [Similar Products]
 UniProt Synonym Gene Names    LIG1; LIG-1 [Similar Products]
 UniProt Entry Name    LRIG1_HUMAN
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 UniProt Comments for LRIG1    LRIG1: a singhle-pass type I membrane protein that acts as a feedback negative regulator of signaling by receptor tyrosine kinases. Regulates cadherin-dependent contact inhibition. Interacts with EGFR, HER2, -3, and -4. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, regulatory subunit; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p14

Cellular Component: integral to membrane

Biological Process: sensory perception of sound; otolith morphogenesis
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 Research Articles on LRIG1    1. Loss of LRIG1 was independently associated with risk of any relapse.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LRIG1 elisa kitDiseases associated with LRIG1 elisa kit
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 ErbB4 Signaling Events Pathway antibodies  ErbB4 Signaling Events Pathway Diagram
 Internalization Of ErbB1 Pathway antibodies  Internalization Of ErbB1 Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By EGFR Pathway antibodies  Signaling By EGFR Pathway Diagram
 Signaling By EGFR In Cancer Pathway antibodies  Signaling By EGFR In Cancer Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >43 publications with LRIG1 and Neoplasms
 Carcinoma Antibodies  >16 publications with LRIG1 and Carcinoma
 Breast Neoplasms Antibodies  >8 publications with LRIG1 and Breast Neoplasms
 Nervous System Diseases Antibodies  >8 publications with LRIG1 and Nervous System Diseases
 Carcinoma, Squamous Cell Antibodies  >7 publications with LRIG1 and Carcinoma, Squamous Cell
 Adenocarcinoma Antibodies  >5 publications with LRIG1 and Adenocarcinoma
 Urinary Bladder Neoplasms Antibodies  >4 publications with LRIG1 and Urinary Bladder Neoplasms
 Skin Neoplasms Antibodies  >4 publications with LRIG1 and Skin Neoplasms
 Kidney Neoplasms Antibodies  >4 publications with LRIG1 and Kidney Neoplasms
 Uterine Cervical Neoplasms Antibodies  >4 publications with LRIG1 and Uterine Cervical Neoplasms
Organs/Tissues associated with LRIG1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >13 publications with LRIG1 and Nerve
 Brain Antibodies  >11 publications with LRIG1 and Brain
 Kidney Antibodies  >6 publications with LRIG1 and Kidney
 Prostate Antibodies  >5 publications with LRIG1 and Prostate
 Intestine Antibodies  >5 publications with LRIG1 and Intestine
 Lung Antibodies  >3 publications with LRIG1 and Lung
 Blood Antibodies  >3 publications with LRIG1 and Blood
 Spleen Antibodies  >2 publications with LRIG1 and Spleen
 Vascular Antibodies  >2 publications with LRIG1 and Vascular
 Stomach Antibodies  >2 publications with LRIG1 and Stomach
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