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LPIN3 elisa kit :: Human lipin 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9342180 LPIN3 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

lipin 3 (LPIN3), ELISA Kit

 Also Known As   

Human Phosphatidate phosphatase LPIN3, LPIN3 ELISA Kit

 Product Synonym Names    Human Phosphatidate phosphatase LPIN3 (LPIN3) ELISA kit; RP4-620E11.3; LIPN3L; SMP2; dJ450M14.2; dJ450M14.3; dJ620E11.2; lipin 3-like; lipin 3
 Product Gene Name   

LPIN3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    605520
 3D Structure    ModBase 3D Structure for Q9BQK8
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LPIN3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LPIN3 purchase    MBS9342180 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the lipin 3 (LPIN3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LPIN3. The ELISA analytical biochemical technique of the MBS9342180 kit is based on LPIN3 antibody-LPIN3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LPIN3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LPIN3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for LPIN3. It may not necessarily be applicable to this product.
 NCBI GI #    74271888
 NCBI GeneID    64900
 NCBI Accession #    NP_075047.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022896.1 [Other Products]
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 UniProt Primary Accession #    Q9BQK8 [Other Products]
 UniProt Secondary Accession #    Q5TDB9; Q9NPY8; Q9UJE5; B2RTT5 [Other Products]
 UniProt Related Accession #    Q9BQK8 [Other Products]
 Molecular Weight    93,614 Da
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 NCBI Official Full Name    phosphatidate phosphatase LPIN3
 NCBI Official Synonym Full Names    lipin 3
 NCBI Official Symbol    LPIN3 [Similar Products]
 NCBI Official Synonym Symbols   
SMP2; LIPN3L; dJ450M14.2; dJ450M14.3; dJ620E11.2
[Similar Products]
 NCBI Protein Information    phosphatidate phosphatase LPIN3; lipin-3
 UniProt Protein Name    Phosphatidate phosphatase LPIN3
 UniProt Synonym Protein Names   
Lipin-3; Lipin-3-like
 Protein Family    Phosphatidate phosphatase
 UniProt Gene Name    LPIN3 [Similar Products]
 UniProt Synonym Gene Names    LIPN3L [Similar Products]
 UniProt Entry Name    LPIN3_HUMAN
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 NCBI Summary for LPIN3    Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3). Human LPIN1 gene has been mapped to 2p25.; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12, respectively. The mouse genes encoding Lpin1, Lpin2, and Lpin3 mapped to chromosome 12, 17, and 2, respectively. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LPIN3    LPIN3: Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Belongs to the lipin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.4

Chromosomal Location of Human Ortholog: 20q12

Cellular Component: endoplasmic reticulum membrane; nucleus

Molecular Function: phosphatidate phosphatase activity; transcription coactivator activity

Biological Process: dephosphorylation; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylcholine biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; triacylglycerol biosynthetic process; fatty acid catabolic process
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 Research Articles on LPIN3    1. a newly identified novel cell-penetrating sequence (LPIN; RRKRRRRRK) from the nuclear localization sequence (NLS) of human nuclear phosphatase, LPIN3.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LPIN3 elisa kitOrgans/Tissues associated with LPIN3 elisa kit
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Triglyceride Biosynthesis Pathway antibodies  Triglyceride Biosynthesis Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with LPIN3 and Kidney
 Liver Antibodies  >1 publications with LPIN3 and Liver
 Muscle Antibodies  >1 publications with LPIN3 and Muscle
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