NP_037376.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,061 Da
NCBI Official Full Name
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
NCBI Official Synonym Full Names
MGAT4 family, member C
NCBI Protein Information
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; gnT-IVc; glcNAc-T IVc; N-acetylglucosaminyltransferase IVc; N-acetylglucosaminyltransferase IV homolog; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine:a-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homolog; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
UniProt Protein Name
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
UniProt Synonym Protein Names
N-acetylglucosaminyltransferase IV homolog; hGnT-IV-H; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; GlcNAc-T IVc; GnT-IVc; N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc
UniProt Synonym Gene Names
hGnT-IV-H; GlcNAc-T IVc; GnT-IVc; N-acetylglucosaminyltransferase IVc [Similar Products]
UniProt Entry Name
MGT4C_HUMAN
UniProt Comments for MGAT4C
MGAT4C: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). Belongs to the glycosyltransferase 54 family.
Protein type: Transferase; EC 2.4.1.145; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q21
Cellular Component: Golgi membrane; integral to membrane
Molecular Function: alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; metal ion binding
Biological Process: cellular protein metabolic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
Research Articles on MGAT4C
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Pathways associated with MGAT4C elisa kit
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