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MRAP2 elisa kit :: Human melanocortin 2 receptor accessory protein 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9317165 MRAP2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

melanocortin 2 receptor accessory protein 2 (MRAP2), ELISA Kit

★Popular Item★
 Also Known As   

Human Melanocortin-2 receptor accessory protein 2, MRAP2 ELISA Kit

 Product Synonym Names    Human Melanocortin-2 receptor accessory protein 2 (MRAP2) ELISA kit; C6orf117; RP11-51G5.2; bA51G5.2; ; melanocortin 2 receptor accessory protein 2
 Product Gene Name   

MRAP2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 615457
 3D Structure    ModBase 3D Structure for Q96G30
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MRAP2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MRAP2 purchase    MBS9317165 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the melanocortin 2 receptor accessory protein 2 (MRAP2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MRAP2. The ELISA analytical biochemical technique of the MBS9317165 kit is based on MRAP2 antibody-MRAP2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MRAP2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MRAP2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Sample Manual Insert of MBS9317165. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MRAP2. It may not necessarily be applicable to this product.
 NCBI GI #    156523251
 NCBI GeneID    112609
 NCBI Accession #    NP_612418.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_138409.2 [Other Products]
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 UniProt Primary Accession #    Q96G30 [Other Products]
 UniProt Secondary Accession #    Q8IXM9; Q8N2D1; A8K9M1 [Other Products]
 UniProt Related Accession #    Q96G30 [Other Products]
 Molecular Weight    23,548 Da
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 NCBI Official Full Name    melanocortin-2 receptor accessory protein 2
 NCBI Official Synonym Full Names    melanocortin 2 receptor accessory protein 2
 NCBI Official Symbol    MRAP2 [Similar Products]
 NCBI Official Synonym Symbols   
BMIQ18; C6orf117; bA51G5.2
[Similar Products]
 NCBI Protein Information    melanocortin-2 receptor accessory protein 2; MC2R accessory protein 2
 UniProt Protein Name    Melanocortin-2 receptor accessory protein 2
 Protein Family    Melanocortin-2 receptor accessory protein
 UniProt Gene Name    MRAP2 [Similar Products]
 UniProt Synonym Gene Names    C6orf117; MC2R accessory protein 2 [Similar Products]
 UniProt Entry Name    MRAP2_HUMAN
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 UniProt Comments for MRAP2    MRAP2: Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo. Belongs to the MRAP family. Homodimer and heterodimer. Forms antiparallel homodimers and heterodimers with MRAP. Interacts with MC1R, MC2R, MC3R, MC4R and MC5R

Chromosomal Location of Human Ortholog: 6q14.2

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; plasma membrane; integral to membrane

Molecular Function: type 5 melanocortin receptor binding; type 3 melanocortin receptor binding; identical protein binding; protein binding; type 4 melanocortin receptor binding; adrenocorticotropin hormone receptor binding

Biological Process: positive regulation of cAMP biosynthetic process; energy reserve metabolic process; feeding behavior

Disease: Body Mass Index Quantitative Trait Locus 18
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 Research Articles on MRAP2    1. In a study of humans with severe, early-onset obesity, they found four rare, potentially pathogenic genetic variants in MRAP2, suggesting that the gene may also contribute to body weight regulation in humans.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with MRAP2 elisa kitOrgans/Tissues associated with MRAP2 elisa kit
 Disease Name  Pubmed Publications
 Drug Toxicity Antibodies  >1 publications with MRAP2 and Drug Toxicity
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with MRAP2 and Brain
 Kidney Antibodies  >1 publications with MRAP2 and Kidney
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