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NEGR1 elisa kit :: Human neuronal growth regulator 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS919685
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

neuronal growth regulator 1 (NEGR1), ELISA Kit

★Popular Item★
 Also Known As   

Human Neuronal growth regulator 1, NEGR1 ELISA Kit

 Product Synonym Names    Human Neuronal growth regulator 1 (NEGR1) ELISA kit; UNQ2433; DMML2433; IGLON4; KILON; MGC46680; Ntra; IgLON family member 4; a kindred of IgLON; neurotractin; neuronal growth regulator 1
 Product Gene Name   

NEGR1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS919685 Testing Data    Testing Data PDF
 OMIM    613173
 3D Structure    ModBase 3D Structure for Q7Z3B1
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human NEGR1. No significant cross-reactivity or interference between Human NEGR1 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, Cell lysates
 Assay Type    Sandwich
 Detection Range    18.75 pg/ml-1200 pg/ml
 Sensitivity    4.69 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Cell Adhesion
 Protein Biological Process 3    Cell adhesion
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NEGR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NEGR1 purchase    MBS919685 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the neuronal growth regulator 1 (NEGR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 18.75 pg/ml-1200 pg/ml in biological research samples containing NEGR1, with an estimated sensitivity of 4.69 pg/ml. The ELISA analytical biochemical technique of the MBS919685 kit is based on NEGR1 antibody-NEGR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NEGR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NEGR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, Cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for NEGR1 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for NEGR1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any NEGR1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for NEGR1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of NEGR1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of NEGR1 elisa kit    NEGR1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS919685. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NEGR1. It may not necessarily be applicable to this product.
 NCBI GI #    66346706
 NCBI GeneID    257194
 NCBI Accession #    NP_776169.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_173808.2 [Other Products]
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 UniProt Primary Accession #    Q7Z3B1 [Other Products]
 UniProt Secondary Accession #    Q5VT21; Q6UY06; Q8NAQ3 [Other Products]
 UniProt Related Accession #    Q7Z3B1 [Other Products]
 Molecular Weight    38,719 Da
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 NCBI Official Full Name    neuronal growth regulator 1
 NCBI Official Synonym Full Names    neuronal growth regulator 1
 NCBI Official Symbol    NEGR1 [Similar Products]
 NCBI Official Synonym Symbols   
Ntra; KILON; IGLON4; DMML2433
[Similar Products]
 NCBI Protein Information    neuronal growth regulator 1; neurotractin; a kindred of IgLON; IgLON family member 4
 UniProt Protein Name    Neuronal growth regulator 1
 UniProt Synonym Protein Names   
IgLON family member 4
 Protein Family    Neuronal growth regulator
 UniProt Gene Name    NEGR1 [Similar Products]
 UniProt Synonym Gene Names    IGLON4; UNQ2433/PRO4993 [Similar Products]
 UniProt Entry Name    NEGR1_HUMAN
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 UniProt Comments for NEGR1    NEGR1: May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain. Belongs to the immunoglobulin superfamily. IgLON family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 1p31.1

Cellular Component: neuron projection; cell surface; cell soma; plasma membrane; intercellular junction

Molecular Function: protein binding

Biological Process: cell-cell adhesion; regulation of neurogenesis; locomotory behavior; feeding behavior
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 Research Articles on NEGR1    1. Data indicate strong associations with severe obesity for single nucleotide polymorphism (SNP) rs9939609 within the FTO gene and SNP rs2815752 near the NEGR1 gene.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NEGR1 elisa kitDiseases associated with NEGR1 elisa kit
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Disease Name  Pubmed Publications
 Obesity Antibodies  >29 publications with NEGR1 and Obesity
 Neoplasms Antibodies  >5 publications with NEGR1 and Neoplasms
 Weight Gain Antibodies  >4 publications with NEGR1 and Weight Gain
 Insulin Resistance Antibodies  >3 publications with NEGR1 and Insulin Resistance
 Gonadal Disorders Antibodies  >2 publications with NEGR1 and Gonadal Disorders
 Hyperinsulinism Antibodies  >2 publications with NEGR1 and Hyperinsulinism
 Hypertension Antibodies  >2 publications with NEGR1 and Hypertension
 Neoplasms, Experimental Antibodies  >1 publications with NEGR1 and Neoplasms, Experimental
 Atherosclerosis Antibodies  >1 publications with NEGR1 and Atherosclerosis
 Dyslipidemias Antibodies  >1 publications with NEGR1 and Dyslipidemias
Organs/Tissues associated with NEGR1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with NEGR1 and Brain
 Adipose Tissue Antibodies  >7 publications with NEGR1 and Adipose Tissue
 Connective Tissue Antibodies  >5 publications with NEGR1 and Connective Tissue
 Kidney Antibodies  >2 publications with NEGR1 and Kidney
 Bone Antibodies  >1 publications with NEGR1 and Bone
 Embryonic Tissue Antibodies  >1 publications with NEGR1 and Embryonic Tissue
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