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NACC1 elisa kit :: Human nucleus accumbens associated 1, BEN and BTB (POZ) domain containing ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9324406 NACC1 elisa kit
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (NACC1), ELISA Kit

 Also Known As   

Human Nucleus accumbens-associated protein 1, NACC1 ELISA Kit

 Product Synonym Names    Human Nucleus accumbens-associated protein 1 (NACC1) ELISA kit; BEND8; BTBD14B; FLJ37383; NAC-1; NAC1; BEN domain containing 8; BTB (POZ) domain containing 14B; transcriptional repressor NAC1; nucleus accumbens associated 1; BEN and BTB (POZ) domain containing
 Product Gene Name   

NACC1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    610672
 3D Structure    ModBase 3D Structure for Q96RE7
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NACC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NACC1 purchase    MBS9324406 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (NACC1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NACC1. The ELISA analytical biochemical technique of the MBS9324406 kit is based on NACC1 antibody-NACC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NACC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NACC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for NACC1. It may not necessarily be applicable to this product.
 NCBI GI #    16418383
 NCBI GeneID    112939
 NCBI Accession #    NP_443108.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_052876.3 [Other Products]
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 UniProt Primary Accession #    Q96RE7 [Other Products]
 UniProt Related Accession #    Q96RE7 [Other Products]
 Molecular Weight    57,258 Da
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 NCBI Official Full Name    nucleus accumbens-associated protein 1
 NCBI Official Synonym Full Names    nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
 NCBI Official Symbol    NACC1 [Similar Products]
 NCBI Official Synonym Symbols   
NAC1; BEND8; NAC-1; BTBD30; BTBD14B
[Similar Products]
 NCBI Protein Information    nucleus accumbens-associated protein 1; BEN domain containing 8; transcriptional repressor NAC1; BTB/POZ domain-containing protein 14B
 UniProt Protein Name    Nucleus accumbens-associated protein 1
 UniProt Synonym Protein Names   
BTB/POZ domain-containing protein 14B
 Protein Family    Nucleus accumbens-associated protein
 UniProt Gene Name    NACC1 [Similar Products]
 UniProt Synonym Gene Names    BTBD14B; NAC1; NAC-1 [Similar Products]
 UniProt Entry Name    NACC1_HUMAN
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 NCBI Summary for NACC1    This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012]
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 UniProt Comments for NACC1    NAC1: Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. Homooligomer; mediated by the BTB domain. Interacts with HDAC3 and HDAC4. Interacts (via BTB domain) with CUL3, PSMD7 AND RCOR1. Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: nucleoplasm; nuclear body; intracellular membrane-bound organelle; cytoplasm; nucleus; cell junction

Biological Process: transcription, DNA-dependent; positive regulation of cell proliferation; negative regulation of transcription, DNA-dependent; protein homooligomerization
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 Research Articles on NACC1    1. NAC1 is essential and sufficient for activation of FOXQ1
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NACC1 elisa kitDiseases associated with NACC1 elisa kit
 Reference Product  PubMed Publications
 HDAC4 elisa kit  >2 publications with NACC1 and HDAC4
 Disease Name  Pubmed Publications
 Substance-Related Disorders Antibodies  >3 publications with NACC1 and Substance-Related Disorders
 Psychoses, Substance-Induced Antibodies  >1 publications with NACC1 and Psychoses, Substance-Induced
 Psychotic Disorders Antibodies  >1 publications with NACC1 and Psychotic Disorders
 Drug Toxicity Antibodies  >1 publications with NACC1 and Drug Toxicity
Organs/Tissues associated with NACC1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >19 publications with NACC1 and Nerve
 Brain Antibodies  >14 publications with NACC1 and Brain
 Embryonic Tissue Antibodies  >3 publications with NACC1 and Embryonic Tissue
 Lymph Node Antibodies  >2 publications with NACC1 and Lymph Node
 Uterus Antibodies  >2 publications with NACC1 and Uterus
 Blood Antibodies  >1 publications with NACC1 and Blood
 Thyroid Antibodies  >1 publications with NACC1 and Thyroid
 Thymus Antibodies  >1 publications with NACC1 and Thymus
 Kidney Antibodies  >1 publications with NACC1 and Kidney
 Skin Antibodies  >1 publications with NACC1 and Skin
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