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PAK1 elisa kit :: Human p21 protein (Cdc42/Rac) -activated kinase 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9330410 PAK1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

p21 protein (Cdc42/Rac) -activated kinase 1 (PAK1), ELISA Kit

 Also Known As   

Human Serine/threonine-protein kinase PAK 1, PAK1 ELISA Kit

 Product Synonym Names    Human Serine/threonine-protein kinase PAK 1 (PAK1) ELISA kit; MGC130000; MGC130001; PAKalpha; STE20 homolog; yeast; p21-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog; yeast) ; p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) ; p21 protein (Cdc42/Rac) -activated kinase 1
 Product Gene Name   

PAK1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    602590
 3D Structure    ModBase 3D Structure for Q13153
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PAK1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PAK1 purchase    MBS9330410 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the p21 protein (Cdc42/Rac) -activated kinase 1 (PAK1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PAK1. The ELISA analytical biochemical technique of the MBS9330410 kit is based on PAK1 antibody-PAK1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PAK1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PAK1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PAK1. It may not necessarily be applicable to this product.
 NCBI GI #    190886457
 NCBI GeneID    5058
 NCBI Accession #    NP_001122092.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001128620.1 [Other Products]
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 UniProt Primary Accession #    Q13153 [Other Products]
 UniProt Secondary Accession #    O75561; Q13567; Q32M53; Q32M54; Q86W79 [Other Products]
 UniProt Related Accession #    Q13153 [Other Products]
 Molecular Weight    60,647 Da
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 NCBI Official Full Name    serine/threonine-protein kinase PAK 1 isoform 1
 NCBI Official Synonym Full Names    p21 protein (Cdc42/Rac)-activated kinase 1
 NCBI Official Symbol    PAK1 [Similar Products]
 NCBI Official Synonym Symbols   
PAKalpha
[Similar Products]
 NCBI Protein Information    serine/threonine-protein kinase PAK 1; p65-PAK; alpha-PAK; STE20 homolog, yeast; p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
 UniProt Protein Name    Serine/threonine-protein kinase PAK 1
 UniProt Synonym Protein Names   
Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK
 Protein Family    Serine/threonine-protein kinase
 UniProt Gene Name    PAK1 [Similar Products]
 UniProt Synonym Gene Names    PAK-1 [Similar Products]
 UniProt Entry Name    PAK1_HUMAN
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 NCBI Summary for PAK1    This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
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 UniProt Comments for PAK1    PAK1: a protein kinase of the STE20 family that regulates cell motility and morphology. Critical RhoGTPase effector that regulates cytoskeleton reorganization, the JNK MAPK pathway, and nuclear signaling. Binding of Rac/cdc42 to the PBD of PAK1 causes autophosphorylation and conformational change. Phosphorylated and activated by PDK.

Protein type: Protein kinase, STE; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; PAKA subfamily

Chromosomal Location of Human Ortholog: 11q13-q14

Cellular Component: Golgi apparatus; nuclear membrane; focal adhesion; protein complex; dendrite; intercellular junction; cytosol; Z disc; ruffle; filamentous actin; growth cone; axon; cytoplasm; plasma membrane

Molecular Function: collagen binding; protein serine/threonine kinase activity; protein binding; protein kinase binding; ATP binding; receptor signaling protein serine/threonine kinase activity; protein kinase activity

Biological Process: axon guidance; positive regulation of JNK activity; exocytosis; wound healing; apoptosis; protein amino acid autophosphorylation; positive regulation of estrogen receptor signaling pathway; receptor clustering; T cell receptor signaling pathway; protein amino acid phosphorylation; positive regulation of stress fiber formation; ephrin receptor signaling pathway; dendrite development; neuromuscular junction development; MAPKKK cascade; positive regulation of peptidyl-serine phosphorylation; branching morphogenesis of a tube; cellular response to insulin stimulus; T cell costimulation; actin cytoskeleton reorganization; response to hypoxia; innate immune response; positive regulation of protein amino acid phosphorylation; mitotic cell cycle; vascular endothelial growth factor receptor signaling pathway; neurite morphogenesis
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 Research Articles on PAK1    1. PAK1 and Snail1 are involved in the formation of estrogen-independent phenotype of breast cancer cells showing the potential role of both proteins as markers of hormone resistance of breast tumors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PAK1 elisa kitPathways associated with PAK1 elisa kit
 Reference Product  PubMed Publications
 CDC42 elisa kit  >269 publications with PAK1 and CDC42
 RAC1 elisa kit  >223 publications with PAK1 and RAC1
 LIMK1 elisa kit  >33 publications with PAK1 and LIMK1
 MAPK1 elisa kit  >24 publications with PAK1 and MAPK1
 EGFR elisa kit  >20 publications with PAK1 and EGFR
 MAP2K1 elisa kit  >14 publications with PAK1 and MAP2K1
 ERBB2 elisa kit  >14 publications with PAK1 and ERBB2
 AKT1 elisa kit  >13 publications with PAK1 and AKT1
 BAD elisa kit  >12 publications with PAK1 and BAD
 GRB2 elisa kit  >10 publications with PAK1 and GRB2
 Products by Pathway  Pathway Diagram
 Activation Of Rac Pathway antibodies  Activation Of Rac Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 Aurora A Signaling Pathway antibodies  Aurora A Signaling Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 CD28 Co-stimulation Pathway antibodies  CD28 Co-stimulation Pathway Diagram
 CD28 Dependent Vav1 Pathway antibodies  CD28 Dependent Vav1 Pathway Diagram
Diseases associated with PAK1 elisa kitOrgans/Tissues associated with PAK1 elisa kit
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >63 publications with PAK1 and Breast Neoplasms
 Gastrointestinal Diseases Antibodies  >24 publications with PAK1 and Gastrointestinal Diseases
 Disease Models, Animal Antibodies  >22 publications with PAK1 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >21 publications with PAK1 and Neoplasm Metastasis
 Cardiovascular Diseases Antibodies  >21 publications with PAK1 and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >18 publications with PAK1 and Adenocarcinoma
 Immune System Diseases Antibodies  >16 publications with PAK1 and Immune System Diseases
 Necrosis Antibodies  >15 publications with PAK1 and Necrosis
 Inflammation Antibodies  >13 publications with PAK1 and Inflammation
 Liver Diseases Antibodies  >12 publications with PAK1 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >78 publications with PAK1 and Blood
 Brain Antibodies  >65 publications with PAK1 and Brain
 Muscle Antibodies  >61 publications with PAK1 and Muscle
 Vascular Antibodies  >59 publications with PAK1 and Vascular
 Kidney Antibodies  >32 publications with PAK1 and Kidney
 Heart Antibodies  >28 publications with PAK1 and Heart
 Lung Antibodies  >28 publications with PAK1 and Lung
 Embryonic Tissue Antibodies  >21 publications with PAK1 and Embryonic Tissue
 Prostate Antibodies  >18 publications with PAK1 and Prostate
 Liver Antibodies  >17 publications with PAK1 and Liver
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