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PXDN elisa kit :: Human peroxidasin homolog (Drosophila) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS907356
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

peroxidasin homolog (Drosophila) (PXDN), ELISA Kit

 Also Known As   

Human Peroxidasin homolog, PXDN ELISA Kit

 Product Synonym Names    Human Peroxidasin homolog (PXDN) ELISA kit; D2S448; D2S448E; KIAA0230; MG50; PRG2; PXN; VPO; p53-responsive gene 2; peroxidasin; peroxidasin homolog (Drosophila)
 Product Gene Name   

PXDN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS907356 Testing Data    Testing Data PDF
 OMIM    605158
 3D Structure    ModBase 3D Structure for Q92626
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human PXDN. No significant cross-reactivity or interference between Human PXDN and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    0.188 ng/ml-12 ng/ml
 Sensitivity    0.04 ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Oxidative Stress
 Protein Biological Process 3    Hydrogen peroxide
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PXDN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PXDN purchase    MBS907356 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the peroxidasin homolog (Drosophila) (PXDN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.188 ng/ml-12 ng/ml in biological research samples containing PXDN, with an estimated sensitivity of 0.04 ng/ml. The ELISA analytical biochemical technique of the MBS907356 kit is based on PXDN antibody-PXDN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PXDN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PXDN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PXDN elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PXDN has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PXDN present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PXDN is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PXDN bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of PXDN elisa kit    PXDN elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS907356. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PXDN. It may not necessarily be applicable to this product.
 NCBI GI #    109150416
 NCBI GeneID    7837
 NCBI Accession #    NP_036425.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012293.2 [Other Products]
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 UniProt Primary Accession #    Q92626 [Other Products]
 UniProt Secondary Accession #    Q4KMG2; A8QM65; D6W4Y0 [Other Products]
 UniProt Related Accession #    Q92626 [Other Products]
 Molecular Weight    165,275 Da
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 NCBI Official Full Name    peroxidasin homolog
 NCBI Official Synonym Full Names    peroxidasin homolog (Drosophila)
 NCBI Official Symbol    PXDN [Similar Products]
 NCBI Official Synonym Symbols   
PXN; VPO; MG50; PRG2; COPOA; D2S448; D2S448E
[Similar Products]
 NCBI Protein Information    peroxidasin homolog; vascular peroxidase 1; p53-responsive gene 2 protein; melanoma-associated antigen MG50
 UniProt Protein Name    Peroxidasin homolog
 UniProt Synonym Protein Names   
Melanoma-associated antigen MG50; Vascular peroxidase 1; p53-responsive gene 2 protein
 UniProt Gene Name    PXDN [Similar Products]
 UniProt Synonym Gene Names    KIAA0230; MG50; PRG2; VPO; VPO1 [Similar Products]
 UniProt Entry Name    PXDN_HUMAN
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 NCBI Summary for PXDN    This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis. [provided by RefSeq, Aug 2014]
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 UniProt Comments for PXDN    PXDN: Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation. Belongs to the peroxidase family. XPO subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Oxidoreductase; EC 1.11.1.7

Chromosomal Location of Human Ortholog: 2p25

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; endoplasmic reticulum

Molecular Function: peroxidase activity; metal ion binding; extracellular matrix structural constituent; heme binding; interleukin-1 receptor antagonist activity

Biological Process: extracellular matrix organization and biogenesis; hydrogen peroxide catabolic process; immune response; negative regulation of cytokine and chemokine mediated signaling pathway; response to oxidative stress

Disease: Corneal Opacification With Other Ocular Anomalies
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 Research Articles on PXDN    1. studies demonstrate the enzymatic properties and substrate specificity of VPO1 are similar to MPO; however, significantly lower catalytic rate constants of VPO1 relative to MPO suggest the possibility of other physiologic roles for this peroxidase
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PXDN elisa kitOrgans/Tissues associated with PXDN elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with PXDN and Neoplasms
 Eye Diseases Antibodies  >1 publications with PXDN and Eye Diseases
 Leukemia, Myeloid Antibodies  >1 publications with PXDN and Leukemia, Myeloid
 Nervous System Diseases Antibodies  >1 publications with PXDN and Nervous System Diseases
 Leukemia, Myeloid, Acute Antibodies  >1 publications with PXDN and Leukemia, Myeloid, Acute
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with PXDN and Brain
 Muscle Antibodies  >1 publications with PXDN and Muscle
 Liver Antibodies  >1 publications with PXDN and Liver
 Vascular Antibodies  >1 publications with PXDN and Vascular
 Eye Antibodies  >1 publications with PXDN and Eye
 Heart Antibodies  >1 publications with PXDN and Heart
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