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PLA2G7 elisa kit :: Human phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS703495 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7), ELISA Kit

★Popular Item★
 Also Known As   

Human lipoprotein-associated phospholipase A2, Lp-PLA2 ELISA Kit

 Product Synonym Names    Human lipoprotein-associated phospholipase A2; Lp-PLA2 ELISA Kit; LDL-PLA2; LP-PLA2; PAFAH; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; PAF 2-acylhydrolase; lipoprotein-associated phospholipase A2; phospholipase A2; ; phospholipase A2; group VII (platelet-activating factor acetylhydrolase; plasma)
 Product Gene Name   

PLA2G7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS703495 Testing Data    Testing Data PDF
 OMIM    gene 614278
 3D Structure    ModBase 3D Structure for Q13093
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human Lp-PLA2. No significant cross-reactivity or interference between human Lp-PLA2 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates.
 Assay Type    Sandwich
 Detection Range    1.56 ng/ml -100 ng/ml.
 Sensitivity    0.39 ng/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PLA2G7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PLA2G7 purchase    MBS703495 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.56 ng/ml -100 ng/ml in biological research samples containing PLA2G7, with an estimated sensitivity of 0.39 ng/ml. The ELISA analytical biochemical technique of the MBS703495 kit is based on PLA2G7 antibody-PLA2G7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLA2G7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLA2G7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PLA2G7 elisa kit

   Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for Lp-PLA2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any Lp-PLA2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for Lp-PLA2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of Lp-PLA2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of PLA2G7 elisa kit    PLA2G7 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS703495. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PLA2G7. It may not necessarily be applicable to this product.
 NCBI GI #    270133071
 NCBI GeneID    7941
 NCBI Accession #    NP_001161829.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001168357.1 [Other Products]
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 UniProt Primary Accession #    Q13093 [Other Products]
 UniProt Secondary Accession #    Q15692; Q5VTT1; Q8IVA2; A5HTT5 [Other Products]
 UniProt Related Accession #    Q13093 [Other Products]
 Molecular Weight    50,077 Da
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 NCBI Official Full Name    platelet-activating factor acetylhydrolase
 NCBI Official Synonym Full Names    phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
 NCBI Official Symbol    PLA2G7 [Similar Products]
 NCBI Official Synonym Symbols   
PAFAD; PAFAH; LP-PLA2; LDL-PLA2
[Similar Products]
 NCBI Protein Information    platelet-activating factor acetylhydrolase; LDL-PLA(2); gVIIA-PLA2; PAF 2-acylhydrolase; PAF acetylhydrolase; group-VIIA phospholipase A2; LDL-associated phospholipase A2; lipoprotein-associated phospholipase A2; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase
 UniProt Protein Name    Platelet-activating factor acetylhydrolase
 UniProt Synonym Protein Names   
1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; Group-VIIA phospholipase A2; gVIIA-PLA2; LDL-associated phospholipase A2; LDL-PLA(2); PAF 2-acylhydrolase
 Protein Family    Platelet-activating factor acetylhydrolase
 UniProt Gene Name    PLA2G7 [Similar Products]
 UniProt Synonym Gene Names    PAFAH; PAF acetylhydrolase; gVIIA-PLA2; LDL-PLA(2) [Similar Products]
 UniProt Entry Name    PAFA_HUMAN
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 NCBI Summary for PLA2G7    The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2009]
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 UniProt Comments for PLA2G7    Function: Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.

Catalytic activity: 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate.
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 Research Articles on PLA2G7    1. Increased Lp-PLA2 levels are associated with an increased risk of re-stenosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PLA2G7 elisa kitPathways associated with PLA2G7 elisa kit
 Reference Product  PubMed Publications
 PLA2G4A elisa kit  >1 publications with PLA2G7 and PLA2G4A
 PLA2G6 elisa kit  >1 publications with PLA2G7 and PLA2G6
 PLA2G2D elisa kit  >1 publications with PLA2G7 and PLA2G2D
 PLA2G2A elisa kit  >1 publications with PLA2G7 and PLA2G2A
 Products by Pathway  Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway antibodies  Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Synthesis, Secretion, And Deacylation Of Ghrelin Pathway antibodies  Synthesis, Secretion, And Deacylation Of Ghrelin Pathway Diagram
Diseases associated with PLA2G7 elisa kitOrgans/Tissues associated with PLA2G7 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >36 publications with PLA2G7 and Cardiovascular Diseases
 Coronary Disease Antibodies  >25 publications with PLA2G7 and Coronary Disease
 Heart Diseases Antibodies  >24 publications with PLA2G7 and Heart Diseases
 Atherosclerosis Antibodies  >20 publications with PLA2G7 and Atherosclerosis
 Inflammation Antibodies  >17 publications with PLA2G7 and Inflammation
 Disease Models, Animal Antibodies  >5 publications with PLA2G7 and Disease Models, Animal
 Hypertension Antibodies  >4 publications with PLA2G7 and Hypertension
 Stroke Antibodies  >4 publications with PLA2G7 and Stroke
 Pain Antibodies  >3 publications with PLA2G7 and Pain
 Necrosis Antibodies  >3 publications with PLA2G7 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with PLA2G7 and Bone
 Connective Tissue Antibodies  >4 publications with PLA2G7 and Connective Tissue
 Heart Antibodies  >3 publications with PLA2G7 and Heart
 Muscle Antibodies  >3 publications with PLA2G7 and Muscle
 Brain Antibodies  >3 publications with PLA2G7 and Brain
 Vascular Antibodies  >2 publications with PLA2G7 and Vascular
 Embryonic Tissue Antibodies  >2 publications with PLA2G7 and Embryonic Tissue
 Ear Antibodies  >1 publications with PLA2G7 and Ear
 Kidney Antibodies  >1 publications with PLA2G7 and Kidney
 Umbilical Cord Antibodies  >1 publications with PLA2G7 and Umbilical Cord
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