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| Product Name
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phospholipase C, beta 2 (PLCB2), ELISA Kit
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| Also Known As
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Human 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-2, PLCB2 ELISA Kit
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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| Request for Current Manual Insert
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| OMIM
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604114
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| 3D Structure
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ModBase 3D Structure for Q00722
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| Species Reactivity
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Human
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| Preparation and Storage
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Store all reagents at 2-8 degree C.
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| Product Note
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Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
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| Other Notes
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Small volumes of PLCB2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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| Searchable Terms for PLCB2 purchase
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MBS2602793 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the phospholipase C, beta 2 (PLCB2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLCB2. The ELISA analytical biochemical technique of the MBS2602793 kit is based on PLCB2 antibody-PLCB2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLCB2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLCB2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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| NCBI/Uniprot data below describe general gene information for PLCB2. It may not necessarily be applicable to this product. |
| NCBI GI #
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546231595
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| NCBI GeneID
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5330
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| NCBI Accession #
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NP_001271226.1
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_001284297.1
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[Other Products]
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| UniProt Primary Accession #
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Q00722
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[Other Products]
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| UniProt Secondary Accession #
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A8K6J2; B9EGH5
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[Other Products]
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| UniProt Related Accession #
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Q00722
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[Other Products]
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| Molecular Weight
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134,024 Da
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[Similar Products]
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| NCBI Official Full Name
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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform 2
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| NCBI Official Synonym Full Names
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phospholipase C, beta 2
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| NCBI Official Symbol
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PLCB2
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[Similar Products]
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| NCBI Official Synonym Symbols
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PLC-beta-2
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[Similar Products]
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| NCBI Protein Information
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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; phosphoinositide phospholipase C-beta-2
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| UniProt Protein Name
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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
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| UniProt Synonym Protein Names
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Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2
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| Protein Family
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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
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| UniProt Gene Name
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PLCB2
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[Similar Products]
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| UniProt Synonym Gene Names
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PLC-beta-2
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[Similar Products]
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| UniProt Entry Name
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PLCB2_HUMAN
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| UniProt Comments for PLCB2
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PLCB2: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.4.11; Carbohydrate Metabolism - inositol phosphate; Phospholipase
Chromosomal Location of Human Ortholog: 15q15
Cellular Component: cytosol
Molecular Function: signal transducer activity; calcium ion binding; phosphoinositide phospholipase C activity; phospholipase C activity
Biological Process: synaptic transmission; inositol phosphate metabolic process; metabolic process; phospholipase C activation; phospholipid metabolic process; sensory perception of bitter taste; lipid catabolic process
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| Research Articles on PLCB2
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1. high expression of CD133 in triple-negative breast cancer (TNBC)-derived cells correlates with high invasive potential; aggressive properties of CD133high cells are mitigated by PLC-beta2 which down-modulates expression of CD133 and may play a role in preventing metastatic progression of CD133 positive TNBC
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Products associated with PLCB2 elisa kit | Pathways associated with PLCB2 elisa kit |
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| Diseases associated with PLCB2 elisa kit | Organs/Tissues associated with PLCB2 elisa kit |
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ELISA Kit 
