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PMEPA1 elisa kit :: Human prostate transmembrane protein, androgen induced 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9338850 PMEPA1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

prostate transmembrane protein, androgen induced 1 (PMEPA1), ELISA Kit

★Popular Item★
 Also Known As   

Human Transmembrane prostate androgen-induced protein, PMEPA1 ELISA Kit

 Product Synonym Names    Human Transmembrane prostate androgen-induced protein (PMEPA1) ELISA kit; STAG1; TMEPAI; OTTHUMP00000174284; solid tumor-associated 1 protein; transmembrane prostate androgen-induced protein; transmembrane; prostate androgen induced RNA; prostate transmembrane protein; androgen induced 1
 Product Gene Name   

PMEPA1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    606564
 3D Structure    ModBase 3D Structure for Q969W9
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Sandwich
 Detection Range    31.2 pg/ml - 1000 pg/ml.
 Sensitivity    5.0 pg/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PMEPA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PMEPA1 purchase    MBS9338850 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the prostate transmembrane protein, androgen induced 1 (PMEPA1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2 pg/ml - 1000 pg/ml in biological research samples containing PMEPA1, with an estimated sensitivity of 5.0 pg/ml. The ELISA analytical biochemical technique of the MBS9338850 kit is based on PMEPA1 antibody-PMEPA1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PMEPA1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PMEPA1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for PMEPA1 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PMEPA1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9338850. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PMEPA1. It may not necessarily be applicable to this product.
 NCBI GI #    364023812
 NCBI GeneID    56937
 NCBI Accession #    NP_001242905.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001255976.1 [Other Products]
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 UniProt Primary Accession #    Q969W9 [Other Products]
 UniProt Secondary Accession #    Q5TDR6; Q8NER4; Q96B72; Q9UJD3 [Other Products]
 UniProt Related Accession #    Q969W9 [Other Products]
 Molecular Weight    31,609 Da
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 NCBI Official Full Name    transmembrane prostate androgen-induced protein isoform d
 NCBI Official Synonym Full Names    prostate transmembrane protein, androgen induced 1
 NCBI Official Symbol    PMEPA1 [Similar Products]
 NCBI Official Synonym Symbols   
STAG1; TMEPAI
[Similar Products]
 NCBI Protein Information    transmembrane prostate androgen-induced protein; solid tumor-associated 1 protein; transmembrane, prostate androgen induced RNA
 UniProt Protein Name    Transmembrane prostate androgen-induced protein
 UniProt Synonym Protein Names   
Solid tumor-associated 1 protein
 Protein Family    Protein
 UniProt Gene Name    PMEPA1 [Similar Products]
 UniProt Synonym Gene Names    STAG1; TMEPAI [Similar Products]
 UniProt Entry Name    PMEPA_HUMAN
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 NCBI Summary for PMEPA1    This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
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 UniProt Comments for PMEPA1    TMEPAI: Involved in down-regulation of the androgen receptor (AR). Enhances ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4. Belongs to the PMEPA1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 20q13.31-q13.33

Cellular Component: Golgi membrane; early endosome membrane; plasma membrane; integral to membrane; endosome membrane

Molecular Function: protein binding; WW domain binding

Biological Process: transforming growth factor beta receptor signaling pathway; androgen receptor signaling pathway; negative regulation of transforming growth factor beta receptor signaling pathway
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 Research Articles on PMEPA1    1. TMEPAI promotes tumorigenic activities in lung cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PMEPA1 elisa kitPathways associated with PMEPA1 elisa kit
 Reference Product  PubMed Publications
 NEDD4 elisa kit  >2 publications with PMEPA1 and NEDD4
 Products by Pathway  Pathway Diagram
 Downregulation Of TGF-beta Receptor Signaling Pathway antibodies  Downregulation Of TGF-beta Receptor Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By TGF-beta Receptor Complex Pathway antibodies  Signaling By TGF-beta Receptor Complex Pathway Diagram
 TGF-beta Receptor Signaling Activates SMADs Pathway antibodies  TGF-beta Receptor Signaling Activates SMADs Pathway Diagram
Diseases associated with PMEPA1 elisa kitOrgans/Tissues associated with PMEPA1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >22 publications with PMEPA1 and Neoplasms
 Prostatic Neoplasms Antibodies  >15 publications with PMEPA1 and Prostatic Neoplasms
 Adenocarcinoma Antibodies  >5 publications with PMEPA1 and Adenocarcinoma
 Carcinoma Antibodies  >5 publications with PMEPA1 and Carcinoma
 Neoplasms, Experimental Antibodies  >4 publications with PMEPA1 and Neoplasms, Experimental
 Intestinal Diseases Antibodies  >3 publications with PMEPA1 and Intestinal Diseases
 Breast Neoplasms Antibodies  >2 publications with PMEPA1 and Breast Neoplasms
 Stomach Neoplasms Antibodies  >2 publications with PMEPA1 and Stomach Neoplasms
 Hyperplasia Antibodies  >2 publications with PMEPA1 and Hyperplasia
 Cell Transformation, Neoplastic Antibodies  >1 publications with PMEPA1 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >19 publications with PMEPA1 and Prostate
 Mammary Gland Antibodies  >2 publications with PMEPA1 and Mammary Gland
 Blood Antibodies  >2 publications with PMEPA1 and Blood
 Stomach Antibodies  >2 publications with PMEPA1 and Stomach
 Intestine Antibodies  >2 publications with PMEPA1 and Intestine
 Ovary Antibodies  >1 publications with PMEPA1 and Ovary
 Esophagus Antibodies  >1 publications with PMEPA1 and Esophagus
 Lung Antibodies  >1 publications with PMEPA1 and Lung
 Liver Antibodies  >1 publications with PMEPA1 and Liver
 Vascular Antibodies  >1 publications with PMEPA1 and Vascular
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