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PCDH12 elisa kit :: Human protocadherin 12 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9317911 PCDH12 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

protocadherin 12 (PCDH12), ELISA Kit

 Also Known As   

Human Protocadherin-12, PCDH12 ELISA Kit

 Product Synonym Names    Human Protocadherin-12 (PCDH12) ELISA kit; VE-cadherin-2; VECAD2; VE-cadherin 2; vascular cadherin-2; vascular endothelial cadherin 2; protocadherin 12
 Product Gene Name   

PCDH12 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    605622
 3D Structure    ModBase 3D Structure for Q9NPG4
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PCDH12 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PCDH12 purchase    MBS9317911 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the protocadherin 12 (PCDH12) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PCDH12. The ELISA analytical biochemical technique of the MBS9317911 kit is based on PCDH12 antibody-PCDH12 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PCDH12 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PCDH12. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PCDH12. It may not necessarily be applicable to this product.
 NCBI GI #    7706113
 NCBI GeneID    51294
 NCBI Accession #    NP_057664.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016580.3 [Other Products]
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 UniProt Primary Accession #    Q9NPG4 [Other Products]
 UniProt Secondary Accession #    Q6UXB6; Q96KB8; Q9H7Y6; Q9H8E0 [Other Products]
 UniProt Related Accession #    Q9NPG4 [Other Products]
 Molecular Weight    128,995 Da
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 NCBI Official Full Name    protocadherin-12
 NCBI Official Synonym Full Names    protocadherin 12
 NCBI Official Symbol    PCDH12 [Similar Products]
 NCBI Official Synonym Symbols   
VECAD2; VE-cadherin-2
[Similar Products]
 NCBI Protein Information    protocadherin-12; VE-cad-2; VE-cadherin 2; vascular cadherin-2; vascular endothelial cadherin 2; vascular endothelial cadherin-2
 UniProt Protein Name    Protocadherin-12
 UniProt Synonym Protein Names   
Vascular cadherin-2; Vascular endothelial cadherin-2; VE-cad-2; VE-cadherin-2
 Protein Family    Protocadherin
 UniProt Gene Name    PCDH12 [Similar Products]
 UniProt Synonym Gene Names    UNQ395/PRO731; VE-cad-2; VE-cadherin-2 [Similar Products]
 UniProt Entry Name    PCD12_HUMAN
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 NCBI Summary for PCDH12    This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PCDH12    PCDH12: Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: integral to plasma membrane; plasma membrane; intercellular junction

Molecular Function: calcium ion binding

Biological Process: glycogen metabolic process; calcium-dependent cell-cell adhesion; neuron recognition; homophilic cell adhesion
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 Research Articles on PCDH12    1. PCDH12 may play an important role in human placental development, and proteolytic cleavage in response to external factors, such as cytokines and pathological settings, regulates its activity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PCDH12 elisa kitOrgans/Tissues associated with PCDH12 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with PCDH12 and Neoplasms
 Adenocarcinoma Antibodies  >1 publications with PCDH12 and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >1 publications with PCDH12 and Neoplasm Metastasis
 Cardiovascular Diseases Antibodies  >1 publications with PCDH12 and Cardiovascular Diseases
 Mouth Neoplasms Antibodies  >1 publications with PCDH12 and Mouth Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >8 publications with PCDH12 and Vascular
 Placenta Antibodies  >5 publications with PCDH12 and Placenta
 Embryonic Tissue Antibodies  >3 publications with PCDH12 and Embryonic Tissue
 Kidney Antibodies  >3 publications with PCDH12 and Kidney
 Uterus Antibodies  >2 publications with PCDH12 and Uterus
 Brain Antibodies  >2 publications with PCDH12 and Brain
 Heart Antibodies  >1 publications with PCDH12 and Heart
 Lung Antibodies  >1 publications with PCDH12 and Lung
 Muscle Antibodies  >1 publications with PCDH12 and Muscle
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