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RSPH4A elisa kit :: Human radial spoke head 4 homolog A (Chlamydomonas) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9339167 RSPH4A elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

radial spoke head 4 homolog A (Chlamydomonas) (RSPH4A), ELISA Kit

 Also Known As   

Human Radial spoke head protein 4 homolog A, RSPH4A ELISA Kit

 Product Synonym Names    Human Radial spoke head protein 4 homolog A (RSPH4A) ELISA kit; CILD11; FLJ37974; MGC126303; RSHL3; RSPH6B; dJ412I7.1; radial spoke head 4 homolog A; radial spokehead-like 3; radial spoke head 4 homolog A (Chlamydomonas)
 Product Gene Name   

RSPH4A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 612649
 3D Structure    ModBase 3D Structure for Q5TD94
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RSPH4A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RSPH4A purchase    MBS9339167 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the radial spoke head 4 homolog A (Chlamydomonas) (RSPH4A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RSPH4A. The ELISA analytical biochemical technique of the MBS9339167 kit is based on RSPH4A antibody-RSPH4A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RSPH4A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RSPH4A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RSPH4A. It may not necessarily be applicable to this product.
 NCBI GI #    58219006
 NCBI GeneID    345895
 NCBI Accession #    NP_001010892.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001010892.2 [Other Products]
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 UniProt Primary Accession #    Q5TD94 [Other Products]
 UniProt Secondary Accession #    Q3KP24; Q5TD95; B4DSI1 [Other Products]
 UniProt Related Accession #    Q5TD94 [Other Products]
 Molecular Weight    80,733 Da
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 NCBI Official Full Name    radial spoke head protein 4 homolog A isoform 1
 NCBI Official Synonym Full Names    radial spoke head 4 homolog A (Chlamydomonas)
 NCBI Official Symbol    RSPH4A [Similar Products]
 NCBI Official Synonym Symbols   
RSHL3; CILD11; RSPH6B; dJ412I7.1
[Similar Products]
 NCBI Protein Information    radial spoke head protein 4 homolog A; radial spokehead-like 3; radial spoke head-like protein 3
 UniProt Protein Name    Radial spoke head protein 4 homolog A
 UniProt Synonym Protein Names   
Radial spoke head-like protein 3
 Protein Family    Radial spoke head protein
 UniProt Gene Name    RSPH4A [Similar Products]
 UniProt Synonym Gene Names    RSHL3 [Similar Products]
 UniProt Entry Name    RSH4A_HUMAN
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 NCBI Summary for RSPH4A    This gene encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
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 UniProt Comments for RSPH4A    RSHL3: Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk which is attached to a subfiber of the outer doublet microtubule, and a bulbous head which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. Defects in RSPH4A are the cause of primary ciliary dyskinesia type 11 (CILD11). CILD is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Belongs to the flagellar radial spoke RSP4/6 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6q22.1

Cellular Component: nucleoplasm; cytoskeleton; nucleolus; axoneme; nucleus

Biological Process: axoneme biogenesis

Disease: Ciliary Dyskinesia, Primary, 11
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 Research Articles on RSPH4A    1. the c.921+3_6delAAGT splice site mutation in RSPH4A is a founder mutation that is a common cause of PCD without situs abnormalities in patients of Hispanic Puerto Rican descent.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with RSPH4A elisa kitOrgans/Tissues associated with RSPH4A elisa kit
 Disease Name  Pubmed Publications
 CILIARY DYSKINESIA, PRIMARY, 11 Antibodies  >1 publications with RSPH4A and CILIARY DYSKINESIA, PRIMARY, 11
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with RSPH4A and Lung
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