NP_005846.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,988 Da
NCBI Official Full Name
receptor activity-modifying protein 1
NCBI Official Synonym Full Names
receptor (G protein-coupled) activity modifying protein 1
NCBI Protein Information
receptor activity-modifying protein 1; CRLR activity-modifying protein 1; receptor activity modifying protein 1; receptor (calcitonin) activity modifying protein 1; calcitonin receptor-like receptor activity modifying protein 1; calcitonin-receptor-like receptor activity-modifying protein 1
UniProt Protein Name
Receptor activity-modifying protein 1
UniProt Synonym Protein Names
Calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1
UniProt Synonym Gene Names
UniProt Entry Name
RAMP1_HUMAN
NCBI Summary for RAMP1
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq, Jul 2008]
UniProt Comments for RAMP1
RAMP1: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL. Belongs to the RAMP family.
Protein type: Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q36-q37.1
Cellular Component: extracellular space; cell surface; integral to plasma membrane; plasma membrane; receptor complex
Molecular Function: protein binding; calcitonin receptor binding; coreceptor activity; receptor activity; protein transporter activity; calcitonin receptor activity
Biological Process: intracellular protein transport; G-protein coupled receptor protein signaling pathway; protein transport; positive regulation of protein amino acid glycosylation; calcium ion transport; receptor internalization; positive regulation of cAMP biosynthetic process; angiogenesis; regulation of G-protein coupled receptor protein signaling pathway
Research Articles on RAMP1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with RAMP1 elisa kit
Pathways associated with RAMP1 elisa kit
Diseases associated with RAMP1 elisa kit
Organs/Tissues associated with RAMP1 elisa kit
|