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RLN1 elisa kit :: Human relaxin 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS702180
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,735 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,135 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

relaxin 1 (RLN1), ELISA Kit

 Also Known As   

Human Relaxin, RLN ELISA Kit

 Product Synonym Names    Human Relaxin; RLN ELISA Kit; H1; RLXH1; bA12D24.3.1; bA12D24.3.2; preprorelaxin H1; prorelaxin; relaxin H1; relaxin 1
 Product Gene Name   

RLN1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 MBS702180 Testing Data    Testing Data PDF
 OMIM    179730
 3D Structure    ModBase 3D Structure for P04808
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human RLN1. No significant cross-reactivity or interference between Human RLN1 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    6.25 pg/ml-400 pg/ml
 Sensitivity    1.56 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of RLN1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RLN1 purchase    MBS702180 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the relaxin 1 (RLN1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards render a theoretical kit detection range of 6.25 pg/ml-400 pg/ml in biological research samples containing RLN1, with an estimated sensitivity of 1.56 pg/ml. The ELISA analytical biochemical technique of the MBS702180 kit is based on RLN1 antibody-RLN1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RLN1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RLN1. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for RLN1 elisa kit

   For Sample: For the quantitative determination of human relaxin (RLN) concentrations in serum, plasma, tissue homogenates.

PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for relaxin has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any relaxin present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for relaxin is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of relaxin bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of RLN1 elisa kit    RLN1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS702180
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NCBI/Uniprot data below describe general gene information for RLN1. It may not necessarily be applicable to this product.
 NCBI GI #    5902052
 NCBI GeneID    6013
 NCBI Accession #    NP_008842.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006911.3 [Other Products]
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 UniProt Primary Accession #    P04808 [Other Products]
 UniProt Secondary Accession #    Q99936; Q9UQJ1 [Other Products]
 UniProt Related Accession #    P04808 [Other Products]
 Molecular Weight    21,146 Da
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 NCBI Official Full Name    prorelaxin H1 preproprotein
 NCBI Official Synonym Full Names    relaxin 1
 NCBI Official Symbol    RLN1 [Similar Products]
 NCBI Official Synonym Symbols   
H1; H1RLX; RLXH1; bA12D24.3.1; bA12D24.3.2
[Similar Products]
 NCBI Protein Information    prorelaxin H1; preprorelaxin H1
 UniProt Protein Name    Prorelaxin H1
 Protein Family    Prorelaxin
 UniProt Gene Name    RLN1 [Similar Products]
 UniProt Entry Name    REL1_HUMAN
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 NCBI Summary for RLN1    Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]
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 UniProt Comments for RLN1    Function: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
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 Research Articles on RLN1    1. For the first time, we bring together the systemic (ovarian) and autocrine/paracrine (intrauterine) sources of RLN, in an attempt to understand how RLN contributes to premature birth in women.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RLN1 elisa kitPathways associated with RLN1 elisa kit
 Reference Product  PubMed Publications
 RLN3 elisa kit  >9 publications with RLN1 and RLN3
 RXFP1 elisa kit  >8 publications with RLN1 and RXFP1
 INSL3 elisa kit  >5 publications with RLN1 and INSL3
 RXFP4 elisa kit  >1 publications with RLN1 and RXFP4
 RXFP2 elisa kit  >1 publications with RLN1 and RXFP2
 INSL5 elisa kit  >1 publications with RLN1 and INSL5
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
Diseases associated with RLN1 elisa kitOrgans/Tissues associated with RLN1 elisa kit
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >10 publications with RLN1 and Fibrosis
 Cardiovascular Diseases Antibodies  >6 publications with RLN1 and Cardiovascular Diseases
 Heart Diseases Antibodies  >5 publications with RLN1 and Heart Diseases
 Disease Models, Animal Antibodies  >3 publications with RLN1 and Disease Models, Animal
 Genital Diseases, Male Antibodies  >3 publications with RLN1 and Genital Diseases, Male
 Death Antibodies  >3 publications with RLN1 and Death
 Hypertrophy Antibodies  >3 publications with RLN1 and Hypertrophy
 Nervous System Diseases Antibodies  >2 publications with RLN1 and Nervous System Diseases
 Prostatic Neoplasms Antibodies  >2 publications with RLN1 and Prostatic Neoplasms
 Prostatic Diseases Antibodies  >2 publications with RLN1 and Prostatic Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with RLN1 and Brain
 Prostate Antibodies  >6 publications with RLN1 and Prostate
 Connective Tissue Antibodies  >5 publications with RLN1 and Connective Tissue
 Testis Antibodies  >2 publications with RLN1 and Testis
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