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RTN4R elisa kit :: Human reticulon 4 receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS943996 RTN4R elisa kit
Unit / Price
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,550 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,815 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

reticulon 4 receptor (RTN4R), ELISA Kit

 Also Known As   

Human Reticulon-4 receptor, RTN4R ELISA Kit

 Product Synonym Names    Human Reticulon-4 receptor (RTN4R) ELISA kit; NGR; NOGOR; Nogo-66 receptor; OTTHUMP00000197866; UNQ330/PRO526; nogo receptor; reticulon 4 receptor
 Product Gene Name   

RTN4R elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 MBS943996 Testing Data    Testing Data PDF
 OMIM    605566
 3D Structure    ModBase 3D Structure for Q9BZR6
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human RTN4R. No significant cross-reactivity or interference between human RTN4R and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates.
 Assay Type    Sandwich
 Detection Range    28 pg/ml-1800 pg/ml.
 Sensitivity    7 pg/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of RTN4R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RTN4R purchase    MBS943996 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the reticulon 4 receptor (RTN4R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 28 pg/ml-1800 pg/ml in biological research samples containing RTN4R, with an estimated sensitivity of 7 pg/ml. The ELISA analytical biochemical technique of the MBS943996 kit is based on RTN4R antibody-RTN4R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RTN4R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RTN4R. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for RTN4R elisa kit

   Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for RTN4R has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any RTN4R present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RTN4R is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RTN4R bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS943996
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NCBI/Uniprot data below describe general gene information for RTN4R. It may not necessarily be applicable to this product.
 NCBI GI #    13194201
 NCBI GeneID    65078
 NCBI Accession #    NP_075380.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_023004.5 [Other Products]
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 UniProt Primary Accession #    Q9BZR6 [Other Products]
 UniProt Secondary Accession #    D3DX28 [Other Products]
 UniProt Related Accession #    Q9BZR6 [Other Products]
 Molecular Weight    50,708 Da
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 NCBI Official Full Name    reticulon-4 receptor
 NCBI Official Synonym Full Names    reticulon 4 receptor
 NCBI Official Symbol    RTN4R [Similar Products]
 NCBI Official Synonym Symbols   
NGR; NOGOR
[Similar Products]
 NCBI Protein Information    reticulon-4 receptor; UNQ330/PRO526; nogo receptor; Nogo-66 receptor
 UniProt Protein Name    Reticulon-4 receptor
 UniProt Synonym Protein Names   
Nogo receptor; NgR; Nogo-66 receptor
 Protein Family    Reticulon-4 receptor
 UniProt Gene Name    RTN4R [Similar Products]
 UniProt Synonym Gene Names    NOGOR; UNQ330/PRO526; NgR [Similar Products]
 UniProt Entry Name    RTN4R_HUMAN
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 NCBI Summary for RTN4R    This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RTN4R    RTN4R: Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development. Belongs to the Nogo receptor family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: growth cone; cell surface; endoplasmic reticulum; plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: axonogenesis; nerve growth factor receptor signaling pathway; negative regulation of axonogenesis; regulation of axonogenesis

Disease: Schizophrenia
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 Research Articles on RTN4R    1. This study demonistrated that alterations in DTI metrics suggest white matter microstructural anomalies of the cerebral cortex in 22q11.2DS. Structural differences in ALIC appear to be associated with the Nogo-66 receptor gene.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Human Reticulon-4 receptor, RTN4R ELISA Kit
 Catalog #  Product Name  Catalog #  Product Name
 MBS9375850  Horse Reticulon 4 Receptor (RTN4R) ELISA Kit  MBS9380637  Cavy Reticulon 4 Receptor (RTN4R) ELISA Kit
 MBS9372200  Fish Reticulon 4 Receptor (RTN4R) ELISA Kit  MBS9375458  Goose Reticulon 4 Receptor (RTN4R) ELISA Kit
 MBS9370523  Plant Reticulon 4 Receptor (RTN4R) ELISA Kit  MBS9375681  Sheep Reticulon 4 Receptor (RTN4R) ELISA Kit
 MBS9371369  Monkey Reticulon 4 Receptor (RTN4R) ELISA Kit  MBS9342169  Mouse Reticulon-4 receptor-like 2, RTN4RL2 ELISA Kit
 MBS9373484  Mouse Reticulon 4 Receptor (RTN4R) ELISA Kit  MBS146931  Recombinant Human Reticulon 4 Receptor
Products associated with RTN4R elisa kitPathways associated with RTN4R elisa kit
 Reference Product  PubMed Publications
 MAG elisa kit  >45 publications with RTN4R and MAG
 LINGO1 elisa kit  >10 publications with RTN4R and LINGO1
 RTN4 elisa kit  >2 publications with RTN4R and RTN4
 NGFR elisa kit  >2 publications with RTN4R and NGFR
 Products by Pathway  Pathway Diagram
 P75(NTR)-mediated Signaling Pathway antibodies  P75(NTR)-mediated Signaling Pathway Diagram
Diseases associated with RTN4R elisa kitOrgans/Tissues associated with RTN4R elisa kit
 Disease Name  Pubmed Publications
 Neurodegenerative Diseases Antibodies  >9 publications with RTN4R and Neurodegenerative Diseases
 Schizophrenia Antibodies  >8 publications with RTN4R and Schizophrenia
 Congenital Abnormalities Antibodies  >2 publications with RTN4R and Congenital Abnormalities
 Inflammation Antibodies  >2 publications with RTN4R and Inflammation
 Encephalomyelitis, Autoimmune, Experimental Antibodies  >2 publications with RTN4R and Encephalomyelitis, Autoimmune, Experimental
 Edema Antibodies  >1 publications with RTN4R and Edema
 Drug Toxicity Antibodies  >1 publications with RTN4R and Drug Toxicity
 Nervous System Malformations Antibodies  >1 publications with RTN4R and Nervous System Malformations
 Hemorrhage Antibodies  >1 publications with RTN4R and Hemorrhage
 Gonadal Disorders Antibodies  >1 publications with RTN4R and Gonadal Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >85 publications with RTN4R and Brain
 Eye Antibodies  >12 publications with RTN4R and Eye
 Blood Antibodies  >10 publications with RTN4R and Blood
 Embryonic Tissue Antibodies  >9 publications with RTN4R and Embryonic Tissue
 Bone Antibodies  >3 publications with RTN4R and Bone
 Kidney Antibodies  >3 publications with RTN4R and Kidney
 Lung Antibodies  >1 publications with RTN4R and Lung
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