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RLIM elisa kit :: Human ring finger protein, LIM domain interacting ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9333890 RLIM elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ring finger protein, LIM domain interacting (RLIM), ELISA Kit

 Also Known As   

Human E3 ubiquitin-protein ligase RLIM, RLIM ELISA Kit

 Product Synonym Names    Human E3 ubiquitin-protein ligase RLIM (RLIM) ELISA kit; CTD-2530H13.3; DKFZp686N06224; FLJ25923; FLJ41093; FLJ42887; FLJ45986; MGC15161; NY-REN-43; RNF12; E3 ubiquitin-protein ligase RNF12; OTTHUMP00000023575; ring finger protein 12; ring zinc finger LIM do; ring finger protein; LIM domain interacting
 Product Gene Name   

RLIM elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    300379
 3D Structure    ModBase 3D Structure for Q9NVW2
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of RLIM elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RLIM purchase    MBS9333890 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ring finger protein, LIM domain interacting (RLIM) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RLIM. The ELISA analytical biochemical technique of the MBS9333890 kit is based on RLIM antibody-RLIM antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RLIM antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RLIM. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RLIM. It may not necessarily be applicable to this product.
 NCBI GI #    34452684
 NCBI GeneID    51132
 NCBI Accession #    NP_057204.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_016120.3 [Other Products]
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 UniProt Primary Accession #    Q9NVW2 [Other Products]
 UniProt Secondary Accession #    Q96D38; Q9Y598; B2RBQ1; D3DTE0 [Other Products]
 UniProt Related Accession #    Q9NVW2 [Other Products]
 Molecular Weight    68,549 Da
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 NCBI Official Full Name    E3 ubiquitin-protein ligase RLIM
 NCBI Official Synonym Full Names    ring finger protein, LIM domain interacting
 NCBI Official Symbol    RLIM [Similar Products]
 NCBI Official Synonym Symbols   
RNF12; NY-REN-43
[Similar Products]
 NCBI Protein Information    E3 ubiquitin-protein ligase RLIM; R-LIM; ring finger protein 12; E3 ubiquitin-protein ligase RNF12; renal carcinoma antigen NY-REN-43; RING finger LIM domain-binding protein; ring zinc finger protein NY-REN-43antigen; LIM domain-interacting RING finger protein; ring zinc finger LIM domain binding protein
 UniProt Protein Name    E3 ubiquitin-protein ligase RLIM
 UniProt Synonym Protein Names   
LIM domain-interacting RING finger protein; RING finger LIM domain-binding protein; R-LIM; RING finger protein 12; Renal carcinoma antigen NY-REN-43
 Protein Family    E3 ubiquitin-protein ligase
 UniProt Gene Name    RLIM [Similar Products]
 UniProt Synonym Gene Names    RNF12; R-LIM [Similar Products]
 UniProt Entry Name    RNF12_HUMAN
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 NCBI Summary for RLIM    The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009]
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 UniProt Comments for RLIM    RNF12: E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1. By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, a stochastic process in which one X chromosome is inactivated to minimize sex- related dosage differences of X-encoded genes in somatic cells of female placental mammals. Belongs to the RNF12 family.

Protein type: Ligase; Ubiquitin ligase; Ubiquitin conjugating system; Transcription, coactivator/corepressor; EC 6.3.2.-

Chromosomal Location of Human Ortholog: Xq13-q21

Cellular Component: nucleoplasm; transcriptional repressor complex; cytoplasm; nucleus

Molecular Function: zinc ion binding; ubiquitin-protein ligase activity; transcription corepressor activity; ligase activity

Biological Process: ubiquitin-dependent protein catabolic process; transcription, DNA-dependent; negative regulation of transcription factor activity; protein ubiquitination; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent
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 Research Articles on RLIM    1. hus regulated nucleocytoplasmic shuttling of RLIM/Rnf12 coordinates cellular compartments during mammary alveolar cell survival
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RLIM elisa kitDiseases associated with RLIM elisa kit
 Reference Product  PubMed Publications
 LDB1 elisa kit  >6 publications with RLIM and LDB1
 LHX1 elisa kit  >5 publications with RLIM and LHX1
 LDB2 elisa kit  >3 publications with RLIM and LDB2
 LMO2 elisa kit  >2 publications with RLIM and LMO2
 SIN3A elisa kit  >2 publications with RLIM and SIN3A
 LHX3 elisa kit  >2 publications with RLIM and LHX3
 LHX2 elisa kit  >1 publications with RLIM and LHX2
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >2 publications with RLIM and Immune System Diseases
 Disease Models, Animal Antibodies  >2 publications with RLIM and Disease Models, Animal
 Inflammation Antibodies  >2 publications with RLIM and Inflammation
 Prenatal Injuries Antibodies  >1 publications with RLIM and Prenatal Injuries
 Fibrosis Antibodies  >1 publications with RLIM and Fibrosis
 Breast Neoplasms Antibodies  >1 publications with RLIM and Breast Neoplasms
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with RLIM and Prenatal Exposure Delayed Effects
 Weight Loss Antibodies  >1 publications with RLIM and Weight Loss
 Nervous System Diseases Antibodies  >1 publications with RLIM and Nervous System Diseases
Organs/Tissues associated with RLIM elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with RLIM and Brain
 Eye Antibodies  >4 publications with RLIM and Eye
 Blood Antibodies  >3 publications with RLIM and Blood
 Embryonic Tissue Antibodies  >3 publications with RLIM and Embryonic Tissue
 Placenta Antibodies  >2 publications with RLIM and Placenta
 Bone Antibodies  >2 publications with RLIM and Bone
 Lung Antibodies  >2 publications with RLIM and Lung
 Skin Antibodies  >1 publications with RLIM and Skin
 Muscle Antibodies  >1 publications with RLIM and Muscle
 Kidney Antibodies  >1 publications with RLIM and Kidney
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