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SIAE elisa kit :: Human sialic acid acetylesterase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9319370 SIAE elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

sialic acid acetylesterase (SIAE), ELISA Kit

 Also Known As   

Human Sialate O-acetylesterase, SIAE ELISA Kit

 Product Synonym Names    Human Sialate O-acetylesterase (SIAE) ELISA kit; CSE-C; CSEC; LSE; MGC87009; YSG2; cytosolic sialic acid 9-O-acetylesterase homolog; sialate O-acetylesterase; sialic acid-specific acetylesterase II; sialic acid acetylesterase
 Product Gene Name   

SIAE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 613551
 3D Structure    ModBase 3D Structure for Q9HAT2
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SIAE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SIAE purchase    MBS9319370 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the sialic acid acetylesterase (SIAE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SIAE. The ELISA analytical biochemical technique of the MBS9319370 kit is based on SIAE antibody-SIAE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SIAE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SIAE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SIAE. It may not necessarily be applicable to this product.
 NCBI GI #    321267600
 NCBI GeneID    54414
 NCBI Accession #    NP_001186851.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199922.1 [Other Products]
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 UniProt Primary Accession #    Q9HAT2 [Other Products]
 UniProt Secondary Accession #    Q8IUT9; Q9HAU7; Q9NT71; B3KPB0 [Other Products]
 UniProt Related Accession #    Q9HAT2 [Other Products]
 Molecular Weight    58,315 Da
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 NCBI Official Full Name    sialate O-acetylesterase isoform 2
 NCBI Official Synonym Full Names    sialic acid acetylesterase
 NCBI Official Symbol    SIAE [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    sialate O-acetylesterase; H-Lse; sialic acid-specific acetylesterase II; cytosolic sialic acid 9-O-acetylesterase homolog
 UniProt Protein Name    Sialate O-acetylesterase
 UniProt Synonym Protein Names   
H-Lse; Sialic acid-specific 9-O-acetylesterase
 Protein Family    Sialate O-acetylesterase
 UniProt Gene Name    SIAE [Similar Products]
 UniProt Synonym Gene Names    YSG2 [Similar Products]
 UniProt Entry Name    SIAE_HUMAN
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 NCBI Summary for SIAE    This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
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 UniProt Comments for SIAE    SIAE: Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in SIAE are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Hydrolase; Secreted, signal peptide; EC

Chromosomal Location of Human Ortholog: 11q24

Cellular Component: extracellular space; lysosome

Molecular Function: sialate O-acetylesterase activity

Biological Process: regulation of immune system process; carbohydrate metabolic process

Disease: Autoimmune Disease, Susceptibility To, 6
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 Research Articles on SIAE    1. There is no evidence for SIAE genetic variants affecting patients with vitiligo.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with SIAE elisa kitOrgans/Tissues associated with SIAE elisa kit
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >4 publications with SIAE and Immune System Diseases
 Autoimmune Diseases Antibodies  >4 publications with SIAE and Autoimmune Diseases
 Congenital Abnormalities Antibodies  >2 publications with SIAE and Congenital Abnormalities
 Fetal Diseases Antibodies  >1 publications with SIAE and Fetal Diseases
 Pregnancy Complications Antibodies  >1 publications with SIAE and Pregnancy Complications
 Exophthalmos Antibodies  >1 publications with SIAE and Exophthalmos
 Arthritis, Rheumatoid Antibodies  >1 publications with SIAE and Arthritis, Rheumatoid
 Inflammation Antibodies  >1 publications with SIAE and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with SIAE and Bone
 Mouth Antibodies  >2 publications with SIAE and Mouth
 Liver Antibodies  >1 publications with SIAE and Liver
 Bone Marrow Antibodies  >1 publications with SIAE and Bone Marrow
 Placenta Antibodies  >1 publications with SIAE and Placenta
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