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SRP68 elisa kit :: Human signal recognition particle 68kDa ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9323374 SRP68 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

signal recognition particle 68kDa (SRP68), ELISA Kit

 Also Known As   

Human Signal recognition particle 68 kDa protein, SRP68 ELISA Kit

 Product Synonym Names    Human Signal recognition particle 68 kDa protein (SRP68) ELISA kit; signal recognition particle 68kDa
 Product Gene Name   

SRP68 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    604858
 3D Structure    ModBase 3D Structure for Q9UHB9
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SRP68 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SRP68 purchase    MBS9323374 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the signal recognition particle 68kDa (SRP68) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SRP68. The ELISA analytical biochemical technique of the MBS9323374 kit is based on SRP68 antibody-SRP68 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SRP68 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SRP68. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SRP68. It may not necessarily be applicable to this product.
 NCBI GI #    386781688
 NCBI GeneID    6730
 NCBI Accession #    NP_001247431.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001260502.1 [Other Products]
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 UniProt Primary Accession #    Q9UHB9 [Other Products]
 UniProt Secondary Accession #    Q8NCJ4; Q8WUK2; B3KUU5; B3KWY7; G3V1U4 [Other Products]
 UniProt Related Accession #    Q9UHB9 [Other Products]
 Molecular Weight    70,730 Da
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 NCBI Official Full Name    signal recognition particle subunit SRP68 isoform 2
 NCBI Official Synonym Full Names    signal recognition particle 68kDa
 NCBI Official Symbol    SRP68 [Similar Products]
 NCBI Protein Information    signal recognition particle subunit SRP68; signal recognition particle 68kD; signal recognition particle 68 kDa protein
 UniProt Protein Name    Signal recognition particle subunit SRP68
 UniProt Synonym Protein Names   
Signal recognition particle 68 kDa protein
 Protein Family    Signal recognition particle
 UniProt Gene Name    SRP68 [Similar Products]
 UniProt Synonym Gene Names    SRP68 [Similar Products]
 UniProt Entry Name    SRP68_HUMAN
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 NCBI Summary for SRP68    This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, May 2012]
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 UniProt Comments for SRP68    SRP68: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Belongs to the SRP68 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus; Endoplasmic reticulum; RNA-binding

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: focal adhesion; endoplasmic reticulum; cytoplasm; nucleolus; signal recognition particle, endoplasmic reticulum targeting; ribosome; cytosol

Molecular Function: signal recognition particle binding; signal sequence binding; endoplasmic reticulum signal peptide binding; 7S RNA binding

Biological Process: response to drug; protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; gene expression
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 Research Articles on SRP68    1. study presents the crystal structures of the RNA-binding domain of SRP68 (SRP68-RBD) alone and in complex with SRP RNA and SRP19; data provide the structural basis for eukaryote-specific, SRP68-driven RNA remodeling required for protein translocation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SRP68 elisa kitPathways associated with SRP68 elisa kit
 Reference Product  PubMed Publications
 SRP72 elisa kit  >17 publications with SRP68 and SRP72
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Protein Export Pathway antibodies  Protein Export Pathway Diagram
 Protein Export Pathway antibodies  Protein Export Pathway Diagram
 SRP-dependent Cotranslational Protein Targeting To Membrane Pathway antibodies  SRP-dependent Cotranslational Protein Targeting To Membrane Pathway Diagram
 Translation Pathway antibodies  Translation Pathway Diagram
Organs/Tissues associated with SRP68 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >2 publications with SRP68 and Pancreas
 Prostate Antibodies  >1 publications with SRP68 and Prostate
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