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SLC22A6 elisa kit :: Human solute carrier family 22 (organic anion transporter) , member 6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9323239 SLC22A6 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

solute carrier family 22 (organic anion transporter) , member 6 (SLC22A6), ELISA Kit

 Also Known As   

Human Solute carrier family 22 member 6, SLC22A6 ELISA Kit

 Product Synonym Names    Human Solute carrier family 22 member 6 (SLC22A6) ELISA kit; FLJ55736; HOAT1; MGC45260; OAT1; PAHT; ROAT1; para-aminohippurate transporter; renal organic anion transporter 1; solute carrier family 22 member 6; solute carrier family 22 (organic anion transporter); member 6
 Product Gene Name   

SLC22A6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    607582
 3D Structure    ModBase 3D Structure for Q4U2R8
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SLC22A6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SLC22A6 purchase    MBS9323239 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the solute carrier family 22 (organic anion transporter), member 6 (SLC22A6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC22A6. The ELISA analytical biochemical technique of the MBS9323239 kit is based on SLC22A6 antibody-SLC22A6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC22A6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC22A6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SLC22A6. It may not necessarily be applicable to this product.
 NCBI GI #    20070188
 NCBI GeneID    9356
 NCBI Accession #    NP_004781.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004790.4 [Other Products]
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 UniProt Primary Accession #    Q4U2R8 [Other Products]
 UniProt Secondary Accession #    O95187; O95742; Q7LDA0; Q8N192; Q9NQA6; Q9NQC2; Q9UBG6; Q9UEQ8; A8MY93; B2D0R6 [Other Products]
 UniProt Related Accession #    Q4U2R8 [Other Products]
 Molecular Weight    61,816 Da
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 NCBI Official Full Name    solute carrier family 22 member 6 isoform a
 NCBI Official Synonym Full Names    solute carrier family 22 (organic anion transporter), member 6
 NCBI Official Symbol    SLC22A6 [Similar Products]
 NCBI Official Synonym Symbols   
OAT1; PAHT; HOAT1; ROAT1
[Similar Products]
 NCBI Protein Information    solute carrier family 22 member 6; hPAHT; hROAT1; PAH transporter; organic anion transporter 1; para-aminohippurate transporter; renal organic anion transporter 1
 UniProt Protein Name    Solute carrier family 22 member 6
 UniProt Synonym Protein Names   
Organic anion transporter 1; hOAT1; PAH transporter; hPAHT; Renal organic anion transporter 1; hROAT1
 Protein Family    Solute carrier family
 UniProt Gene Name    SLC22A6 [Similar Products]
 UniProt Synonym Gene Names    OAT1; PAHT; hOAT1; hPAHT; hROAT1 [Similar Products]
 UniProt Entry Name    S22A6_HUMAN
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 NCBI Summary for SLC22A6    The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SLC22A6    SLC22A6: Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS). Mediates the sodium-independent uptake of p- aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3'-azido- 3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro- phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2- furanpropionate (CMPF), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2- phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p- chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid. PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 11q12.3

Cellular Component: protein complex; integral to plasma membrane; basolateral plasma membrane; plasma membrane; caveola

Molecular Function: protein binding; protein homodimerization activity; inorganic anion exchanger activity; organic anion transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; chloride ion binding

Biological Process: sodium-independent organic anion transport; alpha-ketoglutarate transport; response to methotrexate; transmembrane transport; protein homooligomerization; organic anion transport
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 Research Articles on SLC22A6    1. The results confirmed that OAT1, OAT3, OCT2, MATE1, and MATE2-K were coexpressed in tubular epithelial cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with SLC22A6 elisa kitDiseases associated with SLC22A6 elisa kit
 Products by Pathway  Pathway Diagram
 Organic Anion Transport Pathway antibodies  Organic Anion Transport Pathway Diagram
 Organic Cation/anion/zwitterion Transport Pathway antibodies  Organic Cation/anion/zwitterion Transport Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >20 publications with SLC22A6 and Kidney Diseases
 Drug Toxicity Antibodies  >13 publications with SLC22A6 and Drug Toxicity
 Acute Kidney Injury Antibodies  >10 publications with SLC22A6 and Acute Kidney Injury
 Renal Insufficiency Antibodies  >8 publications with SLC22A6 and Renal Insufficiency
 Inflammation Antibodies  >3 publications with SLC22A6 and Inflammation
 Liver Diseases Antibodies  >3 publications with SLC22A6 and Liver Diseases
 Cholestasis Antibodies  >3 publications with SLC22A6 and Cholestasis
 Kidney Failure, Chronic Antibodies  >2 publications with SLC22A6 and Kidney Failure, Chronic
 Gout Antibodies  >2 publications with SLC22A6 and Gout
 Hypertension Antibodies  >2 publications with SLC22A6 and Hypertension
Organs/Tissues associated with SLC22A6 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >85 publications with SLC22A6 and Kidney
 Brain Antibodies  >9 publications with SLC22A6 and Brain
 Muscle Antibodies  >1 publications with SLC22A6 and Muscle
 Uncharacterized Tissue Antibodies  >1 publications with SLC22A6 and Uncharacterized Tissue
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