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SLC9A3R1 elisa kit :: Human solute carrier family 9 (sodium/hydrogen exchanger) , member 3 regulator 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9334205 SLC9A3R1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

solute carrier family 9 (sodium/hydrogen exchanger) , member 3 regulator 1 (SLC9A3R1), ELISA Kit

★Popular Item★
 Also Known As   

Human Na (+) /H (+) exchange regulatory cofactor NHE-RF1, SLC9A3R1 ELISA Kit

 Product Synonym Names    Human Na (+) /H (+) exchange regulatory cofactor NHE-RF1 (SLC9A3R1) ELISA kit; EBP50; NHERF; NHERF1; NPHLOP2; Na+/H+ exchange regulatory co-factor; ezrin-radixin-moesin binding phosphoprotein-50; sodium/hydrogen exchanger regulatory factor 1; solute carrier family 9 (sodium/hydro; solute carrier family 9 (sodium/hydrogen exchanger); member 3 regulator 1
 Product Gene Name   

SLC9A3R1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 612287
 3D Structure    ModBase 3D Structure for O14745
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml.
 Sensitivity    The sensitivity of this kit is 0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SLC9A3R1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SLC9A3R1 purchase    MBS9334205 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (SLC9A3R1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing SLC9A3R1, with an estimated sensitivity of The sensitivity of this kit is 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9334205 kit is based on SLC9A3R1 antibody-SLC9A3R1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC9A3R1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC9A3R1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SLC9A3R1 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SLC9A3R1 (hereafter termed this analyte) in undiluted original Human body fluids, tissue homogenates, secretions and feces samples.
Sample Manual Insert of MBS9334205. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SLC9A3R1. It may not necessarily be applicable to this product.
 NCBI GI #    4759140
 NCBI GeneID    9368
 NCBI Accession #    NP_004243.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004252.4 [Other Products]
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 UniProt Primary Accession #    O14745 [Other Products]
 UniProt Secondary Accession #    O43552; Q86WQ5; B3KY21 [Other Products]
 UniProt Related Accession #    O14745 [Other Products]
 Molecular Weight    38,868 Da
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 NCBI Official Full Name    Na(+)/H(+) exchange regulatory cofactor NHE-RF1
 NCBI Official Synonym Full Names    solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
 NCBI Official Symbol    SLC9A3R1 [Similar Products]
 NCBI Official Synonym Symbols   
EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2
[Similar Products]
 NCBI Protein Information    Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Na+/H+ exchange regulatory co-factor; regulatory cofactor of Na(+)/H(+) exchanger; ezrin-radixin-moesin binding phosphoprotein-50; ezrin-radixin-moesin-binding phosphoprotein 50; solute carrier family 9 isoform A3 regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
 UniProt Protein Name    Na(+)/H(+) exchange regulatory cofactor NHE-RF1
 UniProt Synonym Protein Names   
Ezrin-radixin-moesin-binding phosphoprotein 50; EBP50; Regulatory cofactor of Na(+)/H(+) exchanger; Sodium-hydrogen exchanger regulatory factor 1; Solute carrier family 9 isoform A3 regulatory factor 1
 Protein Family    Na(+)/H(+) exchange regulatory cofactor
 UniProt Gene Name    SLC9A3R1 [Similar Products]
 UniProt Synonym Gene Names    NHERF; NHERF1; NHERF-1; EBP50 [Similar Products]
 UniProt Entry Name    NHRF1_HUMAN
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 NCBI Summary for SLC9A3R1    This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]
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 UniProt Comments for SLC9A3R1    NHERF: a scaffold protein that connects plasma membrane proteins with members of the Ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized beta-2-adrenergic receptor Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: centrosome; microvillus; intracellular membrane-bound organelle; brush border membrane; endomembrane system; actin cytoskeleton; lipid raft; ruffle; membrane; microvillus membrane; apical plasma membrane; cytoplasm; plasma membrane; nucleus; vesicle; filopodium

Molecular Function: protein binding; chloride channel regulator activity; protein self-association; beta-2 adrenergic receptor binding; beta-catenin binding; protein complex binding; dopamine receptor binding; protein complex scaffold; PDZ domain binding; phosphatase binding; receptor binding

Biological Process: bile acid secretion; negative regulation of protein kinase B signaling cascade; Wnt receptor signaling pathway; renal sodium ion transport; microvillus biogenesis; negative regulation of cell proliferation; cellular phosphate ion homeostasis; regulation of sodium:hydrogen antiporter activity; protein complex assembly; dopamine receptor, phospholipase C activating pathway; regulation of protein kinase activity; negative regulation of sodium:hydrogen antiporter activity; actin cytoskeleton organization and biogenesis; negative regulation of cell migration; dopamine receptor, adenylate cyclase activating pathway; negative regulation of phosphoinositide 3-kinase cascade

Disease: Nephrolithiasis/osteoporosis, Hypophosphatemic, 2
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 Research Articles on SLC9A3R1    1. VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCepsilon-dependent manner.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SLC9A3R1 elisa kitPathways associated with SLC9A3R1 elisa kit
 Reference Product  PubMed Publications
 GNB2L1 elisa kit  >1 publications with SLC9A3R1 and GNB2L1
 CFTR elisa kit  >1 publications with SLC9A3R1 and CFTR
 Products by Pathway  Pathway Diagram
 PDGFR-beta Signaling Pathway antibodies  PDGFR-beta Signaling Pathway Diagram
 Thromboxane A2 Receptor Signaling Pathway antibodies  Thromboxane A2 Receptor Signaling Pathway Diagram
Diseases associated with SLC9A3R1 elisa kitOrgans/Tissues associated with SLC9A3R1 elisa kit
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >5 publications with SLC9A3R1 and Immune System Diseases
 Inflammation Antibodies  >2 publications with SLC9A3R1 and Inflammation
 Cardiovascular Diseases Antibodies  >1 publications with SLC9A3R1 and Cardiovascular Diseases
 Fibrosis Antibodies  >1 publications with SLC9A3R1 and Fibrosis
 Liver Diseases Antibodies  >1 publications with SLC9A3R1 and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with SLC9A3R1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4 publications with SLC9A3R1 and Bone
 Blood Antibodies  >2 publications with SLC9A3R1 and Blood
 Brain Antibodies  >1 publications with SLC9A3R1 and Brain
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