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SPTBN1 elisa kit :: Human spectrin, beta, non-erythrocytic 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9329768 SPTBN1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

spectrin, beta, non-erythrocytic 1 (SPTBN1), ELISA Kit

 Also Known As   

Human Spectrin beta chain, brain 1, SPTBN1 ELISA Kit

 Product Synonym Names    Human Spectrin beta chain; brain 1 (SPTBN1) ELISA kit; ELF; SPTB2; betaSpII; beta-G spectrin; beta-fodrin; beta-spectrin 2; beta-spectrin II; embryonic liver beta-fodrin; spectrin; beta; non-erythrocytic 1
 Product Gene Name   

SPTBN1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    182790
 3D Structure    ModBase 3D Structure for Q01082
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SPTBN1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SPTBN1 purchase    MBS9329768 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the spectrin, beta, non-erythrocytic 1 (SPTBN1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SPTBN1. The ELISA analytical biochemical technique of the MBS9329768 kit is based on SPTBN1 antibody-SPTBN1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SPTBN1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SPTBN1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SPTBN1. It may not necessarily be applicable to this product.
 NCBI GI #    112382250
 NCBI GeneID    6711
 NCBI Accession #    NP_003119.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003128.2 [Other Products]
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 UniProt Primary Accession #    Q01082 [Other Products]
 UniProt Secondary Accession #    O60837; Q16057; Q53R99; Q59ER3; Q8IX99; B2RP63 [Other Products]
 UniProt Related Accession #    Q01082 [Other Products]
 Molecular Weight    274,609 Da
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 NCBI Official Full Name    spectrin beta chain, non-erythrocytic 1 isoform 1
 NCBI Official Synonym Full Names    spectrin, beta, non-erythrocytic 1
 NCBI Official Symbol    SPTBN1 [Similar Products]
 NCBI Official Synonym Symbols   
ELF; SPTB2; HEL102; betaSpII
[Similar Products]
 NCBI Protein Information    spectrin beta chain, non-erythrocytic 1; beta-fodrin; beta-G spectrin; beta-spectrin 2; beta-II spectrin; beta-spectrin II; fodrin beta chain; embryonic liver beta-fodrin; spectrin beta chain, brain 1; epididymis luminal protein 102; beta-spectrin non-erythrocytic 1; spectrin, non-erythroid beta chain 1
 UniProt Protein Name    Spectrin beta chain, non-erythrocytic 1
 UniProt Synonym Protein Names   
Beta-II spectrin; Fodrin beta chain; Spectrin, non-erythroid beta chain 1
 Protein Family    Spectrin
 UniProt Gene Name    SPTBN1 [Similar Products]
 UniProt Synonym Gene Names    SPTB2 [Similar Products]
 UniProt Entry Name    SPTB2_HUMAN
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 NCBI Summary for SPTBN1    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SPTBN1    SPTBN1: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Belongs to the spectrin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: spectrin; protein complex; cytoplasm; nucleolus; M band; axolemma; cytosol

Molecular Function: calmodulin binding; protein binding; structural constituent of cytoskeleton; protein complex binding; phospholipid binding; ankyrin binding; actin binding

Biological Process: axon guidance; plasma membrane organization and biogenesis; cytokinesis after mitosis; actin filament capping; Golgi to plasma membrane protein transport; common-partner SMAD protein phosphorylation; SMAD protein nuclear translocation
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 Research Articles on SPTBN1    1. genetic association study in population of 1,012 Han women in China: Data suggest that an SNP in SPTBN1 (rs11898505) is associated with osteoporotic fractures and bone mineral density of lumbar spine in aging women.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SPTBN1 elisa kitPathways associated with SPTBN1 elisa kit
 Reference Product  PubMed Publications
 EPB41L3 elisa kit  >1 publications with SPTBN1 and EPB41L3
 YWHAG elisa kit  >1 publications with SPTBN1 and YWHAG
 SPTAN1 elisa kit  >1 publications with SPTBN1 and SPTAN1
 NF2 elisa kit  >1 publications with SPTBN1 and NF2
 ANK2 elisa kit  >1 publications with SPTBN1 and ANK2
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Interaction Between L1 And Ankyrins Pathway antibodies  Interaction Between L1 And Ankyrins Pathway Diagram
 L1CAM Interactions Pathway antibodies  L1CAM Interactions Pathway Diagram
 NCAM Signaling For Neurite Out-growth Pathway antibodies  NCAM Signaling For Neurite Out-growth Pathway Diagram
 NCAM Signaling For Neurite Out-growth Pathway antibodies  NCAM Signaling For Neurite Out-growth Pathway Diagram
 Nephrin Interactions Pathway antibodies  Nephrin Interactions Pathway Diagram
Diseases associated with SPTBN1 elisa kitOrgans/Tissues associated with SPTBN1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with SPTBN1 and Neoplasms
 Hematologic Diseases Antibodies  >3 publications with SPTBN1 and Hematologic Diseases
 Neurologic Manifestations Antibodies  >2 publications with SPTBN1 and Neurologic Manifestations
 Leukemia Antibodies  >2 publications with SPTBN1 and Leukemia
 Nervous System Diseases Antibodies  >2 publications with SPTBN1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with SPTBN1 and Disease Models, Animal
 Pancreatitis Antibodies  >1 publications with SPTBN1 and Pancreatitis
 Eye Abnormalities Antibodies  >1 publications with SPTBN1 and Eye Abnormalities
 Inflammation Antibodies  >1 publications with SPTBN1 and Inflammation
 Pancreatic Neoplasms Antibodies  >1 publications with SPTBN1 and Pancreatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >5 publications with SPTBN1 and Bone
 Muscle Antibodies  >4 publications with SPTBN1 and Muscle
 Brain Antibodies  >4 publications with SPTBN1 and Brain
 Lung Antibodies  >3 publications with SPTBN1 and Lung
 Heart Antibodies  >3 publications with SPTBN1 and Heart
 Nerve Antibodies  >2 publications with SPTBN1 and Nerve
 Eye Antibodies  >2 publications with SPTBN1 and Eye
 Placenta Antibodies  >2 publications with SPTBN1 and Placenta
 Blood Antibodies  >2 publications with SPTBN1 and Blood
 Bone Marrow Antibodies  >2 publications with SPTBN1 and Bone Marrow
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