NP_006452.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
134,422 Da
NCBI Official Full Name
sperm-associated antigen 5
NCBI Official Synonym Full Names
sperm associated antigen 5
NCBI Protein Information
sperm-associated antigen 5; astrin; mitotic spindle associated protein p126; mitotic spindle-associated protein p126; mitotic spindle coiled-coil related protein
UniProt Protein Name
Sperm-associated antigen 5
UniProt Synonym Protein Names
Astrin; Deepest; Mitotic spindle-associated protein p126; MAP126
UniProt Synonym Gene Names
UniProt Entry Name
SPAG5_HUMAN
NCBI Summary for SPAG5
This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. [provided by RefSeq, Jul 2008]
UniProt Comments for SPAG5
SPAG5: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: kinetochore; nucleoplasm; spindle pole; cytoplasm; microtubule organizing center; midbody; nucleus
Molecular Function: protein binding
Biological Process: regulation of attachment of spindle microtubules to kinetochore; mitotic sister chromatid segregation; cell division; spindle organization and biogenesis; chromosome segregation
Research Articles on SPAG5
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Products associated with SPAG5 elisa kit
Diseases associated with SPAG5 elisa kit
Organs/Tissues associated with SPAG5 elisa kit
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