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SFTPC elisa kit :: Human surfactant protein C ELISA Kit

Scan QR to view Datasheet Catalog #    MBS702157
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

surfactant protein C (SFTPC), ELISA Kit

★Popular Item★
 Also Known As   

Human Pulmonary surfactant-associated protein C, SP-C ELISA Kit

 Product Synonym Names    Human Pulmonary surfactant-associated protein C; SP-C ELISA Kit; PSP-C; SFTP2; SMDP2; SP-C; pulmonary surfactant apoprotein-2 SP-C; surfactant; pulmonary-associated protein C; surfactant protein C
 Product Gene Name   

SFTPC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS702157 Testing Data    Testing Data PDF
 OMIM    610913
 3D Structure    ModBase 3D Structure for P11686
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human SP-C. No significant cross-reactivity or interference between human SP-C and analogues was observed.
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 Samples    serum, plasma, cell culture supernates, urine
 Assay Type    Quantitative Sandwich
 Detection Range    9.38 pg/ml -600 pg/ml
 Sensitivity    <2.3 pg/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SFTPC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SFTPC purchase    MBS702157 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the surfactant protein C (SFTPC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 9.38 pg/ml -600 pg/ml in biological research samples containing SFTPC, with an estimated sensitivity of <2.3 pg/ml. The ELISA analytical biochemical technique of the MBS702157 kit is based on SFTPC antibody-SFTPC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SFTPC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SFTPC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as serum, plasma, cell culture supernates, urine. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SFTPC elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SP-C has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SP-C present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SP-C is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SP-C bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of SFTPC elisa kit    SFTPC elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS702157. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SFTPC. It may not necessarily be applicable to this product.
 NCBI GI #    288915543
 NCBI GeneID    6440
 NCBI Accession #    NP_001165828.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001172357.1 [Other Products]
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 UniProt Primary Accession #    P11686 [Other Products]
 UniProt Secondary Accession #    P11687; Q12793; Q7Z5D0; A6XNE4; B2RE00; E9PGX3 [Other Products]
 UniProt Related Accession #    P11686 [Other Products]
 Molecular Weight    21,053 Da
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 NCBI Official Full Name    pulmonary surfactant-associated protein C isoform 2 proprotein
 NCBI Official Synonym Full Names    surfactant protein C
 NCBI Official Symbol    SFTPC [Similar Products]
 NCBI Official Synonym Symbols   
SP-C; PSP-C; SFTP2; SMDP2; BRICD6
[Similar Products]
 NCBI Protein Information    pulmonary surfactant-associated protein C; SP5; BRICHOS domain containing 6; pulmonary surfactant apoprotein-2 SP-C; pulmonary surfactant-associated proteolipid SPL(Val)
 UniProt Protein Name    Pulmonary surfactant-associated protein C
 UniProt Synonym Protein Names   
Pulmonary surfactant-associated proteolipid SPL(Val); SP5
 Protein Family    Pulmonary surfactant-associated protein
 UniProt Gene Name    SFTPC [Similar Products]
 UniProt Synonym Gene Names    SFTP2; SP-C [Similar Products]
 UniProt Entry Name    PSPC_HUMAN
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 NCBI Summary for SFTPC    This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
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 UniProt Comments for SFTPC    Function: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
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 Research Articles on SFTPC    1. Structural modeling of transmembrane (BRICHOS) domains of SFTPC precursor and BRI2/ITM2B (integral membrane protein 2B) identifies conserved region structurally complementary to beta-sheet-/amyloid-prone regions in BRICHOS domain-containing proteins.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SFTPC elisa kitPathways associated with SFTPC elisa kit
 Reference Product  PubMed Publications
 SFTPB elisa kit  >29 publications with SFTPC and SFTPB
 SCGB1A1 elisa kit  >17 publications with SFTPC and SCGB1A1
 NKX2-1 elisa kit  >10 publications with SFTPC and NKX2-1
 SFTPA2 elisa kit  >7 publications with SFTPC and SFTPA2
 SFTPA1 elisa kit  >6 publications with SFTPC and SFTPA1
 SFTPD elisa kit  >5 publications with SFTPC and SFTPD
 ETV5 elisa kit  >1 publications with SFTPC and ETV5
 DNAJC10 elisa kit  >1 publications with SFTPC and DNAJC10
 FGF7 elisa kit  >1 publications with SFTPC and FGF7
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Diseases associated with SFTPC elisa kitOrgans/Tissues associated with SFTPC elisa kit
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >135 publications with SFTPC and Lung Diseases
 Fibrosis Antibodies  >44 publications with SFTPC and Fibrosis
 Lung Injury Antibodies  >39 publications with SFTPC and Lung Injury
 Pneumonia Antibodies  >32 publications with SFTPC and Pneumonia
 Inflammation Antibodies  >25 publications with SFTPC and Inflammation
 Idiopathic Pulmonary Fibrosis Antibodies  >24 publications with SFTPC and Idiopathic Pulmonary Fibrosis
 Lung Neoplasms Antibodies  >15 publications with SFTPC and Lung Neoplasms
 Hyperplasia Antibodies  >12 publications with SFTPC and Hyperplasia
 Acute Lung Injury Antibodies  >8 publications with SFTPC and Acute Lung Injury
 Necrosis Antibodies  >6 publications with SFTPC and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with SFTPC and Bone
 Connective Tissue Antibodies  >4 publications with SFTPC and Connective Tissue
 Heart Antibodies  >3 publications with SFTPC and Heart
 Muscle Antibodies  >3 publications with SFTPC and Muscle
 Brain Antibodies  >3 publications with SFTPC and Brain
 Vascular Antibodies  >2 publications with SFTPC and Vascular
 Embryonic Tissue Antibodies  >2 publications with SFTPC and Embryonic Tissue
 Ear Antibodies  >1 publications with SFTPC and Ear
 Kidney Antibodies  >1 publications with SFTPC and Kidney
 Umbilical Cord Antibodies  >1 publications with SFTPC and Umbilical Cord
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