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TAC4 elisa kit :: Human tachykinin 4 (hemokinin) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602776
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $260 +1 FREE 8GB USB
96-Strip-Wells  /  $405 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

tachykinin 4 (hemokinin) (TAC4), ELISA Kit

★Popular Item★
 Also Known As   

Human Tachykinin-4, TAC4 ELISA Kit

 Product Gene Name   

TAC4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    607833
 3D Structure    ModBase 3D Structure for Q86UU9
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 Species Reactivity    Human
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 Specificity    No cross-reaction with other factors.
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 Samples    Serum, plasma or cell culture supernatant and organizations in the natural and recombinant TAC-4 concentration
 Assay Type    Sandwich
 Detection Range    10 ng/ml-0.156 ng/ml
 Sensitivity    0.05 ng/ml.
 Intra-assay Precision    ? 8%
 Inter-assay Precision    ? 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TAC4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TAC4 purchase    MBS2602776 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tachykinin 4 (hemokinin) (TAC4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 10 ng/ml-0.156 ng/ml in biological research samples containing TAC4, with an estimated sensitivity of 0.05 ng/ml. The ELISA analytical biochemical technique of the MBS2602776 kit is based on TAC4 antibody-TAC4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TAC4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TAC4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma or cell culture supernatant and organizations in the natural and recombinant TAC-4 concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TAC4 elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human TAC-4 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of TAC4 elisa kit    TAC4 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2602776. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TAC4. It may not necessarily be applicable to this product.
 NCBI GI #    117938258
 NCBI GeneID    255061
 NCBI Accession #    NP_001070971.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001077503.1 [Other Products]
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 UniProt Primary Accession #    Q86UU9 [Other Products]
 UniProt Secondary Accession #    Q2M2P1; Q6ECK8; Q86UU6; Q86UU7; Q86UU8; Q8IWZ7 [Other Products]
 UniProt Related Accession #    Q86UU9 [Other Products]
 Molecular Weight    12,305 Da [Similar Products]
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 NCBI Official Full Name    tachykinin-4 isoform beta
 NCBI Official Synonym Full Names    tachykinin 4 (hemokinin)
 NCBI Official Symbol    TAC4 [Similar Products]
 NCBI Official Synonym Symbols   
EK; HK1; HK-1; PPT-C
[Similar Products]
 NCBI Protein Information    tachykinin-4; endokinin; preprotachykinin-C
 UniProt Protein Name    Tachykinin-4
 UniProt Synonym Protein Names   
Preprotachykinin-C; PPT-C
 Protein Family    Tachykinin
 UniProt Gene Name    TAC4 [Similar Products]
 UniProt Synonym Gene Names    PPT-C; EKA; EKA/B; EKC [Similar Products]
 UniProt Entry Name    TKN4_HUMAN
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 NCBI Summary for TAC4    This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TAC4    TAC4: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin- C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility. Belongs to the tachykinin family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21.33

Cellular Component: extracellular region

Molecular Function: receptor binding

Biological Process: tachykinin signaling pathway; regulation of blood pressure; positive regulation of saliva secretion
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 Research Articles on TAC4    1. HKs emerge as pivotal endogenous regulators of angiogenesis through neurokinin-1 receptor
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TAC4 elisa kitPathways associated with TAC4 elisa kit
 Reference Product  PubMed Publications
 TACR1 elisa kit  >23 publications with TAC4 and TACR1
 TACR2 elisa kit  >4 publications with TAC4 and TACR2
 TACR3 elisa kit  >3 publications with TAC4 and TACR3
 Products by Pathway  Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
Diseases associated with TAC4 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >10 publications with TAC4 and Inflammation
 Nervous System Diseases Antibodies  >9 publications with TAC4 and Nervous System Diseases
 Edema Antibodies  >2 publications with TAC4 and Edema
 Liver Diseases Antibodies  >1 publications with TAC4 and Liver Diseases
 Hyperplasia Antibodies  >1 publications with TAC4 and Hyperplasia
 Necrosis Antibodies  >1 publications with TAC4 and Necrosis
 Asthma Antibodies  >1 publications with TAC4 and Asthma
 Respiratory Hypersensitivity Antibodies  >1 publications with TAC4 and Respiratory Hypersensitivity
 Genetic Predisposition to Disease Antibodies  >1 publications with TAC4 and Genetic Predisposition to Disease
 Neoplasms Antibodies  >1 publications with TAC4 and Neoplasms
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