NP_005716.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,148 Da
NCBI Official Full Name
tetraspanin-2
NCBI Official Synonym Full Names
tetraspanin 2
NCBI Protein Information
tetraspanin-2; tetraspan 2; tetraspan NET-3; tetraspan TM4SF; new EST tetraspan 3; tetraspanin 2 isoform
UniProt Protein Name
Tetraspanin-2
UniProt Synonym Protein Names
Tetraspan NET-3
UniProt Synonym Gene Names
UniProt Entry Name
TSN2_HUMAN
NCBI Summary for TSPAN2
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
UniProt Comments for TSPAN2
TSPAN2: May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath. Belongs to the tetraspanin (TM4SF) family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1p13.2
Cellular Component: integral to membrane; plasma membrane; myelin sheath
Biological Process: myelination; microglia development; oligodendrocyte differentiation; brain development; inflammatory response; astrocyte development
Research Articles on TSPAN2
Precautions
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Disclaimer
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Diseases associated with TSPAN2 elisa kit
Organs/Tissues associated with TSPAN2 elisa kit
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